KIDNEY INT:重度慢性肾脏疾病患者预后分析!

2018-03-13 xing.T MedSci原创

由此可见,在严重CKD患者中,老年和/或较重的合并症负担、死亡和长期护理明显多于终末期肾病。因此,临床医生、患者和家属在决定肾脏替代治疗时都应该考虑这些风险的相对大小。

在慢性肾脏疾病(CKD)和合并症的老年人中,死亡或残疾的风险会降低肾衰竭的风险。近日,肾脏病领域权威杂志kidney international上发表了一篇研究文章,研究人员进行了一项回顾性人群队列研究,评估了47228名严重非透析依赖CKD患者的年龄和合并症负担不良后果的相对可能性。

研究人员使用29种经过验证的算法用于管理数据和评估死亡、终末期肾病(ESRD)、心血管疾病(CVD)事件和长期护理。

在五年的随访期间,53.4%的患者死亡,24.1%的患者发生心血管事件,14.3%的患者需要长期护理,5.3%的患者发生终末期肾病。在80岁以上和60-79岁的参与者中死亡分别是终末期肾病可能性的145倍和11倍;在80岁以上和60-79岁的参与者中需要长期照顾分别是终末期肾病可能性的30倍和1.7倍。增加的合并症负担与死亡风险增加和长期护理相似,但降低了终末期肾病的可能性,并且增加年龄的风险也有类似的增量。

由此可见,在严重CKD患者中,老年和/或较重的合并症负担、死亡和长期护理明显多于终末期肾病。因此,临床医生、患者和家属在决定肾脏替代治疗时都应该考虑这些风险的相对大小。

原始出处:


Marcello Tonelli ,et al. A population-based cohort study defines prognoses in severe chronic kidney disease.kidney-international.2018.https://doi.org/10.1016/j.kint.2017.12.013

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    2018-03-15 gwc389
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    2018-03-14 三生有幸9135

    学习一下谢谢分享

    0

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    2018-03-13 131****2916

    不错的文章值得推荐

    0

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    2018-03-13 清风拂面

    谢谢分享学习

    0

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