JACC:左房纤维化会增加房颤患者心脑血管不良事件发生风险

2017-09-13 MedSci MedSci原创

左房纤维化严重程度是房颤患者消融成功的关键因素之一,并与患者的卒中、高血压和心衰病史呈相关性。然而,严重的左房纤维化是否会增加房颤患者的主要心脑血管不良事件(MACCE)尚属未知。本回顾性研究纳入了2007年1月至2015年6月1228名行心脏磁共振检查左房纤维化程度的房颤患者,根据严重程度对其进行分组,并随访评估其MACCE发生的概率,包括卒中或短暂性脑缺血发作(TIA)、心梗、急性失代偿心衰或

左房纤维化严重程度是房颤患者消融成功的关键因素之一,并与患者的卒中、高血压和心衰病史呈相关性。然而,严重的左房纤维化是否会增加房颤患者的主要心脑血管不良事件(MACCE)尚属未知。本回顾性研究纳入了2007年1月至2015年6月1228名行心脏磁共振检查左房纤维化程度的房颤患者,根据严重程度对其进行分组,并随访评估其MACCE发生的概率,包括卒中或短暂性脑缺血发作(TIA)、心梗、急性失代偿心衰或心源性死亡。在随访期间,共有62例卒中或TIA、42例心梗、156例心衰和38例心源性死亡事件发生。在疾病危险评分分层分析后,Ⅳ级患者与Ι级患者的MACCE复合发生率的HR值为1.67(95%Cl 1.01 - 2.76)。此外,MACCE中单独与分层评分呈相关性的只有卒中或TIA(HR:3.94; 95% Cl: 1.72 - 8.98)。本研究结果显示,左房纤维化程度的增高会增加房颤患者主要心脑血管不良事件发生的风险。原始出处:Jordan B et al.Left Atrial Fibrosis and Risk of Cerebrovascular and Cardiovascular

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level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Thu Sep 14 12:11:51 CST 2017, time=2017-09-14, status=1, ipAttribution=)]
    2017-12-05 hbwxf
  2. 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    2017-09-17 lou.minghong

    学习了谢谢分享!

    0

  3. 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    2017-09-16 130****4638

    学习了谢谢分享

    0

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level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Thu Sep 14 12:11:51 CST 2017, time=2017-09-14, status=1, ipAttribution=)]
    2017-09-15 1391e9f2a7m

    学习了.加油吧

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/07/20/71f2c82f2515186c4d565a27af9ac6f3.jpg, createdBy=84562001987, createdName=午后阳光, createdTime=Thu Sep 14 16:51:22 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243954, encodeId=7440243954b8, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Sep 14 13:52:58 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243914, encodeId=1da424391463, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Thu Sep 14 12:11:51 CST 2017, time=2017-09-14, status=1, ipAttribution=)]
    2017-09-14 1e1b8538m79(暂无匿称)

    不错的文章.值得一读

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/07/20/71f2c82f2515186c4d565a27af9ac6f3.jpg, createdBy=84562001987, createdName=午后阳光, createdTime=Thu Sep 14 16:51:22 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243954, encodeId=7440243954b8, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Sep 14 13:52:58 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243914, encodeId=1da424391463, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Thu Sep 14 12:11:51 CST 2017, time=2017-09-14, status=1, ipAttribution=)]
    2017-09-14 午后阳光

    感谢分享.学习了

    0

  9. 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level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Thu Sep 14 12:11:51 CST 2017, time=2017-09-14, status=1, ipAttribution=)]
    2017-09-14 惠映实验室

    学习了.谢谢.

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/07/20/71f2c82f2515186c4d565a27af9ac6f3.jpg, createdBy=84562001987, createdName=午后阳光, createdTime=Thu Sep 14 16:51:22 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243954, encodeId=7440243954b8, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Sep 14 13:52:58 CST 2017, time=2017-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=243914, encodeId=1da424391463, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Thu Sep 14 12:11:51 CST 2017, time=2017-09-14, status=1, ipAttribution=)]
    2017-09-14 1e0ece0dm09(暂无匿称)

    学习了

    0

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