Heart:与直系亲属相比,二叶主动脉瓣患者的节段性主动脉僵硬

2018-08-10 xiangting MedSci原创

主动脉窦水平的僵硬度增加与BAV患者的主动脉扩张无关,这与其他节段僵硬度和扩张之间的经典关系正相反。

这项研究旨在比较二叶主动脉瓣(BAV)患者与直系亲属升主动脉各节段的僵硬指数,并比较与BAV形态和功能相关的主动脉僵硬节段性分析。

连续性纳入BAV基准中心的219例BAV患者和148例直系亲属(无BAV)。基于心动周期节段性动脉直径的变化和血压对主动脉和颈动脉僵硬度进行超声评估。

未经调整时,BAV患者的升主动脉各节段均较对照组更僵硬(主动脉窦僵硬指数:17.0±10.9 vs 8.9±6.1,p<0.001;管状主动脉:20.4±31.3 vs 12.7±4.8 ,p=0.04)。然而,在调整主动脉直径和年龄后,只有主动脉窦仍然更僵硬(p<0.001),管状主动脉不再有差异(p=0.610)。在BAV患者中,主动脉直径不受瓣膜形态类型的影响,除了弓形,弓形在1-非冠状窦-右侧BAV亚型时更为扩张:36.1 vs 27.6 mm,p<0.001。主动脉瓣返流与主动脉窦(p<0.001)和管状主动脉(p=0.04)水平的主动脉直径增加相关。

主动脉窦水平的僵硬度增加与BAV患者的主动脉扩张无关,这与其他节段僵硬度和扩张之间的经典关系正相反。需要在每个主动脉段评估僵硬度和临床影响之间的关系。

原始出处:

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    2018-08-12 zhaojie88
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    2018-08-12 slcumt
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    2018-08-11 1ddf0692m34(暂无匿称)

    学习了,长知识

    0

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