J Cereb Blood Flow Metab:大脑中动脉狭窄没有症状?ASL告诉你侧支循环灌注的差异!

2017-08-11 shaosai MedSci原创

近年来出现的伪连续ASL(pseudo-continuous ASL, pCASL)技术,具有全脑成像、信噪比和标记有效率高、人体组织能量吸收及磁转移效应低的优点,尤以3D-ASL为代表,成为促进ASL广泛临床应用的契机。本研究通过利用3D伪连续ASL(3D pCASL)比较2个标记后延迟时间(PLD)来评估症状组和无症状组单侧大脑中动脉(MCA)侧支循环功能的差异性,并将结果发表在J Cereb

近年来出现的伪连续ASL(pseudo-continuous ASL, pCASL)技术,具有全脑成像、信噪比和标记有效率高、人体组织能量吸收及磁转移效应低的优点,尤以3D-ASL为代表,成为促进ASL广泛临床应用的契机。本研究通过利用3D伪连续ASL(3D pCASL)比较2个标记后延迟时间(PLD)来评估症状组和无症状组单侧大脑中动脉(MCA)侧支循环功能的差异性,并将结果发表在J Cereb Blood Flow Metab上。本研究共纳入了81例单侧MCA狭窄程度≥50%的患者,并行2个标记后延迟时间的pCASL。分别比较症状组和无症状组患者在MCA区域2个PLDs的平均CBF和CBF剪影图像。结果为,与无症状组患者相比,症状组在MCA狭窄区域的每个PLD的CBF要明显减低。在症状组,PLAD1.5-2.5s期间狭窄侧MCA区域的CBF要比正常侧MCA供血区域明显增高。在无症状组,PLAD1.5-2.5s,狭窄侧MCA区域的CBF同样要比正常侧MCA供血区域明显增高,然而,症状组患者血流明显减慢。在CBF剪影图像上,与症状组相比,无症状组在PLD1.5s和2.5s异常区域体积差

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  1. 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
    2017-11-24 一闲
  3. 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
    2018-05-06 guojianrong
  4. 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
    2017-08-30 虈亣靌

    不错的.学习了.谢谢分享!

    0

  5. 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
    2017-08-19 虈亣靌

    讲解的非常好,值得学习

    0

  6. 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
  8. 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
    2017-08-13 lq1771
  9. [GetPortalCommentsPageByObjectIdResponse(id=1634444, encodeId=3578163444498, content=<a href='/topic/show?id=e6084385876' target=_blank style='color:#2F92EE;'>#大脑中动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43858, encryptionId=e6084385876, topicName=大脑中动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=376422174069, createdName=楚钟, createdTime=Wed Sep 27 07:49:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896130, encodeId=eff51896130b5, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
    2017-08-12 虈亣靌

    不错的,学习了!谢谢分享!

    0

  10. 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time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232760, encodeId=3b88232e60f9, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sat Aug 12 08:27:56 CST 2017, time=2017-08-12, status=1, ipAttribution=)]
    2017-08-12 meiliwuxian

    学习一下

    0

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背景:闭塞动脉的下游的静脉血流可影响缺血性卒中患者的预后。研究者旨在应用动态CT血管造影评估皮层静脉充盈(CVF)情况,并且评估其与临床预后的关系。方法:大脑中动脉近端闭塞患者在卒中发病后9小时内行CT平扫及全脑CT灌注/动态CT血管造影。研究者定义不良预后为改良Rankin量表评分≥3。应用泊松回归分析CVF范围和速率和3个月不良预后的相关性。除外年龄,卒中的严重程度、治疗方式、ASPECT评分

Neurology:无症状大脑中动脉狭窄闭塞,高分辨MRI显示深部微小侧枝流空

目的:在这项研究中,研究者旨在探讨高分辨率MRI(HRMRI)下,狭窄闭塞大脑中动脉(MCA)患者深部微小侧枝流空(DTFV)的发病率及临床相关性。方法:研究者回顾性分析477例MCA狭窄闭塞的患者的临床资料和HRMRI。DTFV的存在和分布,定义为HRMRI至少2个连续的T2加权图像,观察到MCA周围3个或更多的流动空隙。分析DTFV与狭窄程度(轻度<50%,中度50%~70%,严重70% -

PLoS One:涉及岛叶皮质的缺血性卒中,可能是心源性栓塞的危险因素

目的:评估心源性脑栓塞是否与岛叶部位缺血性脑卒中相关。方法:识别症状开始7天内的住院的缺血性卒中患者。基于弥散加权成像,研究包括大脑中动脉(MCA)中缺血性病变。根据梗死是否涉及岛叶,将患者分为两组中一组。主要预后为根据是否涉及岛叶,比较心源性脑栓塞的频率。共有MCAO供血区发生缺血性卒中的患者,112名(8.5%)涉及到岛叶。与未涉及岛叶(30.4%)的患者相比,涉及岛叶卒中(52.7%)的患者

图解脑供血系统之脑动脉

脑供血系统分为动脉和静脉,各自拥有一定的结构和功能特点。 图1 脑供血系统 一、脑动脉 (一)组成 脑组织的动脉供血由4条大动脉完成,即颈内动脉系统和椎-基地动脉系统。大脑半球前3/5由颈内动脉系统供应;大脑半球后2/5由椎-基底动脉系统供应。 (二)颈总动脉 右侧颈总动脉发自头臂干,左侧颈总动脉直接发自主动脉弓(图2,图3)。 图2

Eur Radiol:双相CT检测血栓长度差异能预测急性缺血性卒中的临床预后

目的:血栓长度可能高估了早期动脉计算机断层扫描血管造影(CTA)对侧枝循环状态检测的能力。基于双相CT检测的血栓长度的等级系统,研究人员评估血栓长度的差异与临床预后的关系。方法:招募了M1阻断的急性缺血性卒中患者48名。双相CT检测包括非对照增强CT,具有自动跟踪技术的CTA以及造影剂注射40s后进行延迟对照增强CT扫描。在CTA和CECT中血栓长度差异用三点量表进行分级:G0=没有差异,G1=血

Stroke :CT灌注中大脑中动脉深部供血区通透性预测脑梗死后出血转化的价值。

CT灌注(CTP)中的通透性(PS)反映了血脑屏障通透性,与出血转化(HT)有关。大脑中动脉(MCA)深部供血区的HT可在大血管闭塞再通后出现。本研究旨在确定HT和MCA深部供血区PS的关系,并将结果发表在Stroke上。