Clinica Chimica Acta:测定溶血指数的更佳波长是什么?

2020-08-10 MedSci原创 MedSci原创

溶血是处理血清标本时常见的问题。溶血指数(HI)为自动分析仪中的溶血提供了警告。但是,目前尚未形成HI标准化,每个实验室都采用了原有的方法。特别是用于HI测量的波长在各个实验室是不尽相同的。

溶血是处理血清标本时常见的问题。溶血指数(HI)为自动分析仪中的溶血提供了警告。但是,目前尚未形成HI标准化,每个实验室都采用了原有的方法。特别是用于HI测量的波长在各个实验室是不尽相同的。因此,本研究关注HI在不同波长下的预警能力。

研究人员选择4种波长类型,测量并计算每个波长HI (410 nm/HI-1、451 nm/HI-2、545 nm/HI-3、571 nm/HI-4)。采用人工溶血标本(AHSs)研究了3种干扰成分对4种HI类型的影响。此外地,还研究了AHSs中HI与血红蛋白浓度(Hb)的关系以及HI与31个生化检测值的关系。

在干扰评估中,只有HI-4对3个干扰分量无影响。Hb与HI-4的相关性非常强(rS = 0.9987)。HI-4升高1个单位,对应Hb升高14.8 mg/dL。

本研究发现HI的最佳波长是在或接近571纳米。

原始出处:

Akiyo Ishiguro,Mitsuaki Nishioka,What is the best wavelength for the measurement of hemolysis index?

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    2020-10-07 丁鹏鹏
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    2020-11-25 windight
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    2020-08-09 ms6000001982608373

    好文

    0

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    2020-08-09 ms5000002046462755

    不错

    0

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