Cell Metab:准妈妈请放轻松,放轻松,不然以后你的女儿很容易出现暴饮暴食的呢

2017-05-31 tulip1999 来宝网

人们普遍认为,压力会引发饮食失调,如暴饮暴食,而女性比男性更为常见。一度认为两者之间存在的这种联系纯粹是心理上的,但现在,研究人员越来越多地转向用遗传学和生物学原因进行解释。一项最新研究表明,小鼠妊娠后期压力增大可重新激活了大脑诱发其雌性后代表现出暴饮暴食的行为。这项研究还表明,暴饮暴食可通过在青春期改变某些营养素之间的平衡加以预防。



【怀孕后期的压力可能会使女儿出现暴饮暴食】人们普遍认为,压力会引发饮食失调,如暴饮暴食,而女性比男性更为常见。一度认为两者之间存在的这种联系纯粹是心理上的,但现在,研究人员越来越多地转向用遗传学和生物学原因进行解释。一项最新研究表明,小鼠妊娠后期压力增大可重新激活了大脑诱发其雌性后代表现出暴饮暴食的行为。这项研究还表明,暴饮暴食可通过在青春期改变某些营养素之间的平衡加以预防

由分别来自以色列魏茨曼科学研究所的研究人员和德国慕尼黑马克斯普朗克精神医学研究所的研究人员共完成的这项研究成果发表在《细胞代谢》杂志上。

暴饮暴食症是指一个人失去了对饮食习惯的控制,并在短时间内反复多次摄入大量食物,即使他们已经饱了或是不饿。

出现暴饮暴食症的人往往都是超重或肥胖的,他们也可能会因此而感到羞愧、内疚或痛苦,而这又可能会导致暴饮暴食更频繁地发作。

在美国,暴饮暴食是最常见的一种饮食失调,大约2.8%的人可能会在某些时刻出现暴饮暴食。

与其他饮食失调一样,暴饮暴食通常始于青春期或成年早期。虽然男女都可以出现,但是女性比男性更为常见,前者是后者的2.5倍。

研究越来越多地揭示了饮食失调(如暴饮暴食)是由遗传、生物、心理和社会因素等多种复杂因素共同引起的。

女孩通常在青春期开始出现暴饮暴食症状。之前,科学家们一直在寻找心理学方面的原因对其进行解释,但是最近,他们也已经把注意力转向生物学方面。

在他们的研究报告中,研究人员解释说,与其他饮食失调一样,暴饮暴食与早期的生活压力,如童年创伤和产科并发症有关。

他们还指出,人们普遍认为,临近出生时或在出生时的应激会对胎儿造成一定影响,并使后代易患“各种精神及代谢疾病”,而男女后代产生的这种患病易感性有所不同。

因此,在他们的调查中,他们用专门饲养的小鼠对产前应激与雌性后代出现暴饮暴食行为之间的联系进行了研究。

共同资深作者,领导魏茨曼科学研究所及马克斯普朗克精神医学研究所进行应激神经生物学研究的Alon Chen教授说,他们“建立了一种模型,确实可以显示早期生活压力会增加雌性后代出现暴饮暴食的可能性。”

研究小组认为,这些研究结果将有助于增加我们对大脑在饮食失调中所起作用的理解,同时也强调了孕妇应尽可能避免在怀孕期间让自己处于紧张的状态,这一点非常重要。Chen教授总结道:

“我们都知道这一点,但人们忽略了导致孕妇紧张的各种社会或经济方面的原因。但是,我们日后因此而付出的代价——无论是精神疾病、代谢综合征,还是与心脏有关的疾病等——在很大程度上都受到我们早期大脑发育进程的影响。”

原始出处:

Mariana Schroeder, Mira Jakovcevski, Tamar Polacheck, et al. A Methyl-Balanced Diet Prevents CRF-Induced Prenatal Stress-Triggered Predisposition to Binge Eating-like Phenotype. Cell Metabolism, 2017.

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    2017-12-03 一闲
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    2017-07-05 维他命
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    2018-03-19 guojianrong
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