JACC:左主干病变的搭桥术治疗——体外循环vs非体外循环

2019-08-30 不详 MedSci原创

本研究的目的旨在评估和比较EXCEL临床试验中的冠脉左主干疾病患者接受体外循环下冠脉搭桥术(CABG)和非体外循环下的预后差异。EXCEL临床试验旨在比较经皮冠脉支架植入治疗和CABG对冠脉左主干病变患者的影响,在923名接受CABG治疗的患者中,有652名患者是在体外循环下做的手术,271名为非体外循环下,分析结果显示,非体外循环组的左回旋支和右冠状动脉血运重建率较低(84.1%比90.0%;p

本研究的目的旨在评估和比较EXCEL临床试验中的冠脉左主干疾病患者接受体外循环下冠脉搭桥术(CABG)和非体外循环下的预后差异。

EXCEL临床试验旨在比较经皮冠脉支架植入治疗和CABG对冠脉左主干病变患者的影响,在923名接受CABG治疗的患者中,有652名患者是在体外循环下做的手术,271名为非体外循环下,分析结果显示,非体外循环组的左回旋支和右冠状动脉血运重建率较低(84.1%比90.0%;p=0.01)(31.1%比40.6%;p=0.007)。经基线差异调整分析后,发现非体外循环组患者的3年死亡率明显更高(8.8% vs. 4.5%;HR: 1.94; 95%Cl: 1.10-3.41; p = 0.02),而死亡、心梗和卒中的复合事件发生风险无明显差异。

研究结果显示,在接受冠脉搭桥治疗的左主干病变患者中,非体外循环组患者的冠脉血运重建率更低,3年死亡风险更高。

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    2020-05-18 hbwxf
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    2019-09-01 zzc2214

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