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BMJ：55岁前发生的高血压遗传，心血管死亡风险更高

2017-05-25 中国循环杂志/许菁 中国循环杂志

高血压死亡风险心血管
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波士顿大学医学院研究人员分析了弗明汉心脏研究中两代受试者的高血压发病及心血管死亡情况表明：早发（<55岁）高血压与其子女发生高血压密切相关，而且与晚发高血压相比，早发高血压的心血管死亡风险更高。研究者发现，如果父母中有一位或者两位是早发高血压，子女患高血压风险分别增加1倍和2.5倍。而晚发高血压患者的子女患高血压风险与无高血压者子女相当。本研究数据显示，在父辈这一代3614例受试者中，随访6

波士顿大学医学院研究人员分析了弗明汉心脏研究中两代受试者的高血压发病及心血管死亡情况表明：早发（<55岁）高血压与其子女发生高血压密切相关，而且与晚发高血压相比，早发高血压的心血管死亡风险更高。

研究者发现，如果父母中有一位或者两位是早发高血压，子女患高血压风险分别增加1倍和2.5倍。而晚发高血压患者的子女患高血压风险与无高血压者子女相当。

本研究数据显示，在父辈这一代3614例受试者中，随访6年，发生1151例心血管死亡，心血管死亡风险随着高血压发病年龄的增加而减少。

进一步分析显示，高血压发病年龄低于45岁的高血压患者较无高血压受试者心血管死亡增加1.2倍、冠心病死亡增加1.3倍。

而高血压发病年龄超过65岁的高血压患者的心血管死亡和冠心病死亡仅增加50%和40%。

作者指出，根据高血压的发病年龄，高血压至少有两种类型，一种是早发高血压，且可能具有遗传特征，而另外一种就是晚发高血压，与不良健康生活方式关系更加密切。

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    2017-11-10 gaoxiaoe

    #BMJ#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1848313, encodeId=50901848313e2, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Nov 10 12:51:00 CST 2017, time=2017-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207066, encodeId=7d9420e0660b, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Tue Jun 06 06:12:46 CST 2017, time=2017-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255640, encodeId=4223125564021, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat May 27 01:51:00 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1554178, encodeId=8c6715541e87a, content=<a href='/topic/show?id=ab025182080' target=_blank style='color:#2F92EE;'>#心血管死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51820, encryptionId=ab025182080, topicName=心血管死亡)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0fb814514579, createdName=huperzia, createdTime=Sat May 27 01:51:00 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629859, encodeId=015f1629859b2, content=<a href='/topic/show?id=a913518225e' target=_blank style='color:#2F92EE;'>#心血管死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51822, encryptionId=a913518225e, topicName=心血管死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e76421361831, createdName=baoya, createdTime=Sat May 27 01:51:00 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=202429, encodeId=785320242987, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Thu May 25 13:46:54 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=202423, encodeId=ae8e20242315, content=每天学一点进步一点, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5vZbLiaw0G6FFQ3J4obXJNXbFJZBOJIsBiasEmSFCxzhibZ2TT0xftAW5kV1SLyo6jg0hOMaJg1Alm15kbuoDUFIsUM4JP7bdvcA/0, createdBy=10082062447, createdName=医无止境。, createdTime=Thu May 25 13:25:40 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=202392, encodeId=458e202392ff, content=继续学习中谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Thu May 25 11:44:09 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=202386, encodeId=8cf620238653, content=学习一下知识了，高血压, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Thu May 25 11:35:06 CST 2017, time=2017-05-25, status=1, ipAttribution=)]
    2017-06-06 laoli

    谢谢分享，学习了！

    0

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    2017-05-27 quxin068

    #死亡风险#

    0

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    2017-05-27 huperzia

    #心血管死亡#

    0

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    2017-05-27 baoya

    #心血管死亡风险#

    0

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    2017-05-25 半夏微凉

    学习了谢谢分享

    0

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    2017-05-25 医无止境。

    每天学一点进步一点

    0

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    2017-05-25 往日如昨

    继续学习中谢谢

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    2017-05-25 flysky120

    学习一下知识了，高血压

    0

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