Ultrasound:超声检查或可提高血管疾病早期检出率

2018-09-01 佚名 嘉音

8月7日,在线发表于《Ultrasound》杂志上的一项研究表明,在血管疾病患者表现出症状前,血管超声就可以提高其早期检出率。动脉粥样硬化和腹主动脉瘤是常见的血管疾病,该疾病平时较为隐匿,但发病时往往危及生命,早期诊断对不良事件的预防至关重要。采用血管超声对动脉血管壁的生物力学指标进行检测,如动脉随心脏收缩和舒张的搏动能力,有可能成为诊断血管疾病的早期指标。莱斯特大学生命科学学院领导的研究团队与莱

8月7日,在线发表于《Ultrasound》杂志上的一项研究表明,在血管疾病患者表现出症状前,血管超声就可以提高其早期检出率。

动脉粥样硬化和腹主动脉瘤是常见的血管疾病,该疾病平时较为隐匿,但发病时往往危及生命,早期诊断对不良事件的预防至关重要。采用血管超声对动脉血管壁的生物力学指标进行检测,如动脉随心脏收缩和舒张的搏动能力,有可能成为诊断血管疾病的早期指标。

莱斯特大学生命科学学院领导的研究团队与莱斯特医院的研究人员合作,对腹主动脉瘤和动脉粥样硬化的小鼠模型进行纵向超声研究。11只小鼠用于制备腹主动脉瘤动物模型,20只小鼠用于制备动脉粥样硬化模型,在疾病发展的不同时期进行超声检查,采用半自动图像处理算法追踪血管壁在心动周期中的运动以评估血管舒张能力,并采用标准的手动分析方法进行比较。

结果表明,腹主动脉瘤小鼠的平均动脉扩张度明显低于对照组,动脉粥样硬化组小鼠的动脉扩张度也与基因型和饮食相关。动脉扩张度下降表明动脉血管壁硬化,或可作为心血管疾病中血管病理变化的早期指标。

该研究的主要作者之一,莱斯特大学的Justyna Janus指出:“随着血管疾病的不断加重,小鼠血管的搏动能力不断下降,这为超声早期发现血管功能下降提供了指标。该研究为未来血管疾病新疗法的开发和验证提供了思路。”

莱斯特大学临床前影像主任,Mike Kelly博士指出:“该研究表明基因和生活方式(饮食)共同影响血管疾病,动脉扩张度下降是血管疾病的早期表现,并且研究证实超声可用于检测血管功能的早期变化,从而提高血管疾病早期检出率。”

原始出处:
Justyna Janus, Baris Kanber, Wadhah Mahbuba, et al. A preclinical ultrasound method for the assessment of vascular disease progression in murine models. Ultrasound 2018 Aug 7. 

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    2019-03-24 zgwhgch
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    2019-06-08 bsmagic9140
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replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18124, encryptionId=a8941812471, topicName=ultrasound)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2cc329519145, createdName=linlin2322, createdTime=Mon Nov 05 06:06:00 CST 2018, time=2018-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1904796, encodeId=1c711904e966a, content=<a href='/topic/show?id=ae97625036d' target=_blank style='color:#2F92EE;'>#检出率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62503, encryptionId=ae97625036d, topicName=检出率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Wed Apr 10 03:06:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1913762, encodeId=10e01913e62f4, content=<a href='/topic/show?id=6f5328e398' target=_blank style='color:#2F92EE;'>#ASO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2873, encryptionId=6f5328e398, topicName=ASO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Thu Jan 17 01:06:00 CST 2019, time=2019-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284304, encodeId=423e128430466, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498471, encodeId=50e114984e190, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342205, encodeId=2fe234220566, content=超声可提高血管疾病早期检出率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sun Sep 02 07:38:08 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342169, encodeId=48b4342169bd, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sun Sep 02 00:36:31 CST 2018, time=2018-09-02, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1796562, encodeId=79401e9656228, content=<a href='/topic/show?id=57211812121' target=_blank style='color:#2F92EE;'>#Ultra#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18121, encryptionId=57211812121, topicName=Ultra)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Tue Sep 11 22:06:00 CST 2018, time=2018-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794237, encodeId=26641e94237e2, content=<a href='/topic/show?id=b1e916559bc' target=_blank style='color:#2F92EE;'>#Sound#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16559, encryptionId=b1e916559bc, topicName=Sound)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10ba218, createdName=zgwhgch, createdTime=Sun Mar 24 16:06:00 CST 2019, time=2019-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1657063, encodeId=8e8f165e063c3, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Sat Jun 08 06:06:00 CST 2019, time=2019-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693976, encodeId=365816939e62b, content=<a href='/topic/show?id=a8941812471' target=_blank style='color:#2F92EE;'>#ultrasound#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18124, encryptionId=a8941812471, topicName=ultrasound)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2cc329519145, createdName=linlin2322, createdTime=Mon Nov 05 06:06:00 CST 2018, time=2018-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1904796, encodeId=1c711904e966a, content=<a href='/topic/show?id=ae97625036d' target=_blank style='color:#2F92EE;'>#检出率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62503, encryptionId=ae97625036d, topicName=检出率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Wed Apr 10 03:06:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1913762, encodeId=10e01913e62f4, content=<a href='/topic/show?id=6f5328e398' target=_blank style='color:#2F92EE;'>#ASO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2873, encryptionId=6f5328e398, topicName=ASO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Thu Jan 17 01:06:00 CST 2019, time=2019-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284304, encodeId=423e128430466, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498471, encodeId=50e114984e190, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342205, encodeId=2fe234220566, content=超声可提高血管疾病早期检出率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sun Sep 02 07:38:08 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342169, encodeId=48b4342169bd, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sun Sep 02 00:36:31 CST 2018, time=2018-09-02, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1796562, encodeId=79401e9656228, content=<a href='/topic/show?id=57211812121' target=_blank style='color:#2F92EE;'>#Ultra#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18121, encryptionId=57211812121, topicName=Ultra)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Tue Sep 11 22:06:00 CST 2018, time=2018-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794237, encodeId=26641e94237e2, content=<a href='/topic/show?id=b1e916559bc' target=_blank style='color:#2F92EE;'>#Sound#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16559, encryptionId=b1e916559bc, topicName=Sound)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10ba218, createdName=zgwhgch, createdTime=Sun Mar 24 16:06:00 CST 2019, time=2019-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1657063, encodeId=8e8f165e063c3, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Sat Jun 08 06:06:00 CST 2019, time=2019-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693976, encodeId=365816939e62b, content=<a href='/topic/show?id=a8941812471' target=_blank style='color:#2F92EE;'>#ultrasound#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18124, encryptionId=a8941812471, topicName=ultrasound)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2cc329519145, createdName=linlin2322, createdTime=Mon Nov 05 06:06:00 CST 2018, time=2018-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1904796, encodeId=1c711904e966a, content=<a href='/topic/show?id=ae97625036d' target=_blank style='color:#2F92EE;'>#检出率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62503, encryptionId=ae97625036d, topicName=检出率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Wed Apr 10 03:06:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1913762, encodeId=10e01913e62f4, content=<a href='/topic/show?id=6f5328e398' target=_blank style='color:#2F92EE;'>#ASO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2873, encryptionId=6f5328e398, topicName=ASO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Thu Jan 17 01:06:00 CST 2019, time=2019-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284304, encodeId=423e128430466, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498471, encodeId=50e114984e190, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342205, encodeId=2fe234220566, content=超声可提高血管疾病早期检出率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sun Sep 02 07:38:08 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342169, encodeId=48b4342169bd, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sun Sep 02 00:36:31 CST 2018, time=2018-09-02, status=1, ipAttribution=)]
    2019-01-17 huangdf
  7. [GetPortalCommentsPageByObjectIdResponse(id=1796562, encodeId=79401e9656228, content=<a href='/topic/show?id=57211812121' target=_blank style='color:#2F92EE;'>#Ultra#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18121, encryptionId=57211812121, topicName=Ultra)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/385F510BDFE0F55A4FFDFDFFD9892943/100, createdBy=a3262500163, createdName=siiner, createdTime=Tue Sep 11 22:06:00 CST 2018, time=2018-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794237, encodeId=26641e94237e2, content=<a href='/topic/show?id=b1e916559bc' target=_blank style='color:#2F92EE;'>#Sound#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16559, encryptionId=b1e916559bc, topicName=Sound)], 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replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18124, encryptionId=a8941812471, topicName=ultrasound)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2cc329519145, createdName=linlin2322, createdTime=Mon Nov 05 06:06:00 CST 2018, time=2018-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1904796, encodeId=1c711904e966a, content=<a href='/topic/show?id=ae97625036d' target=_blank style='color:#2F92EE;'>#检出率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62503, encryptionId=ae97625036d, topicName=检出率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Wed Apr 10 03:06:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1913762, encodeId=10e01913e62f4, content=<a href='/topic/show?id=6f5328e398' target=_blank style='color:#2F92EE;'>#ASO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2873, encryptionId=6f5328e398, topicName=ASO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2e0330, createdName=huangdf, createdTime=Thu Jan 17 01:06:00 CST 2019, time=2019-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284304, encodeId=423e128430466, content=<a href='/topic/show?id=d27a9280461' target=_blank style='color:#2F92EE;'>#超声检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92804, encryptionId=d27a9280461, topicName=超声检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=649f191, createdName=zzc2211, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498471, encodeId=50e114984e190, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Mon Sep 03 12:06:00 CST 2018, time=2018-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342205, encodeId=2fe234220566, content=超声可提高血管疾病早期检出率。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, 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  8. 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  9. 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createdTime=Sun Sep 02 07:38:08 CST 2018, time=2018-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=342169, encodeId=48b4342169bd, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sun Sep 02 00:36:31 CST 2018, time=2018-09-02, status=1, ipAttribution=)]
    2018-09-02 liumin1987

    超声可提高血管疾病早期检出率。

    0

  10. 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    2018-09-02 smartxiuxiu

    有用

    0

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