Gastroenterology:咖啡可降低早期结肠癌患者死亡风险

2017-11-21 zhangfan MedSci原创

研究认为咖啡可降低早期结肠癌患者结肠癌特异性死亡风险和全因死亡风险

近日研究人员考察了结肠癌确诊后,咖啡摄入量与患者死亡率之间的关系。

研究人员考察了护士健康研究(1984 - 2012)和卫生专业人员随访研究(1986-2012)数据,随访研究中共确诊了1599例I或II期结肠癌病例。通过问卷形式得知参试者咖啡的摄入量以及摄入频率,以每天1杯咖啡为参考,考察结肠癌确诊患者咖啡摄入与死亡率之间的关系。

研究平均随访7.8年,其中记录了803例死亡案例,其中188例死于结肠癌。多因素调整后,相比于咖啡0摄入患者,每天摄入咖啡4杯以上的患者其结肠癌特异性死亡风险降低52% (HR 0.48;95% CI, 0.28-0.83),全因死亡风险降低30% (HR,0.70;95% CI,0.54-0.91)。每天2杯以上咖啡因和低因咖啡摄入患者其结肠癌特异性死亡以及全因死亡风险降低。在结肠癌确诊后,相比于每天咖啡摄入量低于2杯的患者,维持2杯以上咖啡摄入的患者其结肠癌特异性死亡风险(HR,0.63;95% CI,0.44-0.89)以及全因死亡风险(HR,0.71;95% CI,0.60-0.85)均显著降低。

研究认为咖啡可降低早期结肠癌患者结肠癌特异性死亡风险和全因死亡风险。

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    2018-02-06 许安
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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/23/557c1f19aaf5459a8405411e38903c4b.jpg, createdBy=dfc02088287, createdName=cscdliu, createdTime=Tue Nov 21 22:50:27 CST 2017, time=2017-11-21, status=1, ipAttribution=)]
  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Thu Nov 23 02:03:00 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263429, encodeId=ba7c2634295e, content=谢谢谢谢谢谢谢谢分享最新研究成果.学习了前沿知识!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aadd1680584, createdName=蔬菜, createdTime=Wed Nov 22 21:22:21 CST 2017, time=2017-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263191, encodeId=a49726319122, content=文章很好.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/23/557c1f19aaf5459a8405411e38903c4b.jpg, createdBy=dfc02088287, createdName=cscdliu, createdTime=Tue Nov 21 22:50:27 CST 2017, time=2017-11-21, status=1, ipAttribution=)]
    2017-12-24 情途末路

    学习了.获益匪浅!感谢分享

    0

  6. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/23/557c1f19aaf5459a8405411e38903c4b.jpg, createdBy=dfc02088287, createdName=cscdliu, createdTime=Tue Nov 21 22:50:27 CST 2017, time=2017-11-21, status=1, ipAttribution=)]
    2017-11-25 大爰

    学习了谢谢分享!!

    0

  7. 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  8. 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  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Thu Nov 23 02:03:00 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263429, encodeId=ba7c2634295e, content=谢谢谢谢谢谢谢谢分享最新研究成果.学习了前沿知识!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aadd1680584, createdName=蔬菜, createdTime=Wed Nov 22 21:22:21 CST 2017, time=2017-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263191, encodeId=a49726319122, content=文章很好.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/23/557c1f19aaf5459a8405411e38903c4b.jpg, createdBy=dfc02088287, createdName=cscdliu, createdTime=Tue Nov 21 22:50:27 CST 2017, time=2017-11-21, status=1, ipAttribution=)]
    2017-11-22 蔬菜

    谢谢谢谢谢谢谢谢分享最新研究成果.学习了前沿知识!

    0

  10. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Thu Nov 23 02:03:00 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263429, encodeId=ba7c2634295e, content=谢谢谢谢谢谢谢谢分享最新研究成果.学习了前沿知识!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aadd1680584, createdName=蔬菜, createdTime=Wed Nov 22 21:22:21 CST 2017, time=2017-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263191, encodeId=a49726319122, content=文章很好.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/23/557c1f19aaf5459a8405411e38903c4b.jpg, createdBy=dfc02088287, createdName=cscdliu, createdTime=Tue Nov 21 22:50:27 CST 2017, time=2017-11-21, status=1, ipAttribution=)]
    2017-11-21 cscdliu

    文章很好.学习了

    0

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