418323例门诊膝关节镜肺栓塞发生率和危险因素

2011-04-02 MedSci原创 MedSci原创

  在2011年2月15-19日召开的美国骨科医师学会年会(AAOS 2011)上,以色列Hetsroni等报告的研究显示,门诊膝关节镜后症状性肺栓塞发生率是0.028%,危险因素包括年龄、手术时间延长、女性,癌症病史也可能是其中之一。   肺栓塞(PE)是膝关节镜后很少见但很严重的并发症,其相关研究资料有限。该研究旨在确定膝关节镜后症状性PE发生率和危险因素。   研究者在纽约卫生

  在2011年2月15-19日召开的美国骨科医师学会年会(AAOS 2011)上,以色列Hetsroni等报告的研究显示,门诊膝关节镜后症状性肺栓塞发生率是0.028%,危险因素包括年龄、手术时间延长、女性,癌症病史也可能是其中之一。

  肺栓塞(PE)是膝关节镜后很少见但很严重的并发症,其相关研究资料有限。该研究旨在确定膝关节镜后症状性PE发生率和危险因素。

  研究者在纽约卫生行政部门数据库中,找到1997-2006年期间施行的膝关节镜手术。病例定义为关节镜后90天内再入院,诊断为PE。潜在的危险因素包括年龄、性别、手术复杂程度、手术室停留时间延长、癌症病史、合并症和麻醉方式。使用logistic回归分析评价各因素与症状性PE危险增加可能性增加的关系。

  该研究共纳入374033例患者接受的418323次膝关节镜手术。PE事件共发生117例(0.028%)。与年龄小于20岁者相比,年龄大于30 岁者PE发生危险增加6倍(P=0.001)。与手术室停留时间不足30 min者相比,手术室停留时间超过90 min危险增加3倍(P< 0.001)。女性危险增加1.5倍(P=0.03)。有癌症病史者危险增加3倍(P=0.06)。麻醉方式、手术复杂程度或合并症评分与PE发生危险不相关。

  症状性肺栓塞在膝关节镜后及其少见,但仍可识别出一些特异性危险因素,包括年龄超过30岁、手术室停留时间超过90 min以及女性,癌症病史也可能是其中之一。

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    2011-04-04 xzw114