Eye:屈光不正的严重程度是否取决于早产儿视网膜病变治疗时激光消融的数量和程度?

2019-09-28 MedSci 网络

Young-Zvandasara T等人近日在Eye杂志上发表了一篇新文章,他们测试了早产儿视网膜病变(ROP)中获得性屈光不正的严重性,取决于所递送激光治疗的数量。

Young-Zvandasara T等人近日在Eye杂志上发表了一篇新文章,他们测试了早产儿视网膜病变(ROP)中获得性屈光不正的严重性,取决于所递送激光治疗的数量。

他们将年龄和体重相匹配的两组接受治疗和未经治疗的婴儿进行对比分析。使用计算机辅助设计软件分析激光烧伤次数和Retcam II视网膜图像的数据,以确定治疗面积的比例。收集数据直到6岁。

该研究包括43名婴儿的86只眼,其中治疗组21例婴儿(42只眼)的平均胎龄(GA)为26.40(±2.5)周,而相匹配的未治疗组为27.30(±1.7)周(P = 0.650)。治疗组的出生体重(BW)为812μg(±86),未治疗组为804μg(±135)(P = 0.185)。治疗组在72个月时的平均屈光不正为-2.23(±4.06),而未治疗组为+2.04(±0.90)(P <0.005)。在72个月时,接受治疗的眼睛中有50%为近视眼,而对照组为19%(P = 0.013)。施加的平均激光烧伤为1855(±659),经视网膜治疗的平均比例为45%(±10)。近视眼的平均治疗面积为49%(±13),远视眼为43%(±10),正视眼为42%(±5)(P =(0.030)。在72个月时发现,更大的治疗范围与高度近视和屈光参差有关(P <0.050)。未发现这些与远视有关。

因此,他们认为,治疗更多数量的激光烧伤或更大比例的视网膜,则视网膜激光消融后发生ROP的近视程度会更高。

原文出处:

Young-Zvandasara, T., et al., Is the severity of refractive error dependent on the quantity and extent of retinal laser ablation for retinopathy of prematurity? Eye (Lond), 2019.

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    2019-09-30 zutt
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    2019-09-30 oliver169
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