J Agr Food Chem:蓝莓提取物可有助于控制牙龈炎症,减少抗生素的使用

2015-09-03 MedSci MedSci原创

牙龈疾病在成年人中较为常见,牙齿上菌斑或生物膜形成时很容易引起牙龈发炎。若疾病进展则最终会导致牙周炎的发生,牙周炎严重时通常会辅助使用抗生素。现在科学家现已经发现野生蓝莓提取物可抑制牙菌斑的形成。该研究成果发表于《农业与食品化学杂志》,此研究成果或可为牙周炎的治疗带来新的方法并可减少抗生素的使用。牙龈炎的发病率很高,很多人患有不同程度的牙龈炎症或牙龈炎,牙龈存在炎症时会表现为牙龈发红,肿胀,容易出

牙龈疾病在成年人中较为常见,牙齿上菌斑或生物膜形成时很容易引起牙龈发炎。若疾病进展则最终会导致牙周炎的发生,牙周炎严重时通常会辅助使用抗生素。现在科学家现已经发现野生蓝莓提取物可抑制牙菌斑的形成。该研究成果发表于《农业与食品化学杂志》,此研究成果或可为牙周炎的治疗带来新的方法并可减少抗生素的使用。

牙龈炎的发病率很高,很多人患有不同程度的牙龈炎症或牙龈炎,牙龈存在炎症时会表现为牙龈发红,肿胀,容易出血,如果放任不管,那么牙龈炎最终会发展为牙周炎。牙菌斑钙化可形成牙石,感染可扩散至龈下,破坏牙周的支持组织。牙周炎一旦形成则无法治愈,只能控制其发展,牙周炎的基础治疗主要包括洁刮治以去除菌斑牙石,有时还需要辅助应用抗生素。但是最近,研究人员已经开始寻找天然的抗菌化合物以治疗牙龈疾病。Daniel Grenier及其同事探究了蓝莓多酚(抗食源性致病菌)是否可抑制具核梭杆菌(牙周炎的一个主要致病菌)。

研究人员在实验室测试了野生蓝莓提取物——Vaccinium angustifolium Ait对具核梭杆菌的抗菌作用,结果发现此富含多酚的提取物确可抑制具核梭杆菌的生长,同时还可抑制菌斑生物膜的形成。此外,该提取物还可阻断炎症反应中的一个分子通路,该通路为牙龈疾病发生过程中的一个关键部分。研究人员表示,他们正在开发一种设备,可在患者接受深部清洁后缓慢释放此提取物,以帮助治疗牙周炎。

原始出处:


Amel Ben Lagha, Stéphanie Dudonné, Yves Desjardins, Daniel Grenier. Wild Blueberry (Vaccinium angustifoliumAit.) Polyphenols TargetFusobacterium nucleatumand the Host Inflammatory Response: Potential Innovative Molecules for Treating Periodontal Diseases. Journal of Agricultural and Food Chemistry, 2015; 63 (31): 6999 DOI: 10.1021/acs.jafc.5b01525

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=125034, encodeId=675212503410, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:48:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715560, encodeId=284b1e155605d, content=<a href='/topic/show?id=a217e58972' target=_blank style='color:#2F92EE;'>#food#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7589, encryptionId=a217e58972, topicName=food)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=68d031960225, createdName=ms6747015003810650, createdTime=Sat Jul 23 02:23:00 CST 2016, time=2016-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351500, encodeId=7fb8135150023, content=<a href='/topic/show?id=d1c76e735bf' target=_blank style='color:#2F92EE;'>#牙龈炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67735, encryptionId=d1c76e735bf, topicName=牙龈炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat Sep 05 09:23:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]
    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=125034, encodeId=675212503410, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:48:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715560, encodeId=284b1e155605d, content=<a href='/topic/show?id=a217e58972' target=_blank style='color:#2F92EE;'>#food#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7589, encryptionId=a217e58972, topicName=food)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=68d031960225, createdName=ms6747015003810650, createdTime=Sat Jul 23 02:23:00 CST 2016, time=2016-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351500, encodeId=7fb8135150023, content=<a href='/topic/show?id=d1c76e735bf' target=_blank style='color:#2F92EE;'>#牙龈炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67735, encryptionId=d1c76e735bf, topicName=牙龈炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat Sep 05 09:23:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=125034, encodeId=675212503410, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:48:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1715560, encodeId=284b1e155605d, content=<a href='/topic/show?id=a217e58972' target=_blank style='color:#2F92EE;'>#food#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7589, encryptionId=a217e58972, topicName=food)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=68d031960225, createdName=ms6747015003810650, createdTime=Sat Jul 23 02:23:00 CST 2016, time=2016-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351500, encodeId=7fb8135150023, content=<a href='/topic/show?id=d1c76e735bf' target=_blank style='color:#2F92EE;'>#牙龈炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67735, encryptionId=d1c76e735bf, topicName=牙龈炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sat Sep 05 09:23:00 CST 2015, time=2015-09-05, status=1, ipAttribution=)]