Hypertension:高盐饮食可以影响皮肤哦!

2017-02-09 MedSci MedSci原创

常规概念表明,身体内的Na +保持在流体和血压稳态的狭窄限度内。然而,一些研究已经表明,可以保留或从体内除去相当量的Na +,而没有相应的水分流失,并且皮肤可以作为主要的盐储库。近期,一项发表在杂志Hypertension上的研究数据显示,与血浆盐储存相比,皮肤是高渗的,这也适用于皮肤间质液。即使在血浆和间质液之间的小电解质梯度可以代表水肿产生力增强。因为水积累是适度的,研究者们决定在大鼠中使用替

常规概念表明,身体内的Na +保持在流体和血压稳态的狭窄限度内。然而,一些研究已经表明,可以保留或从体内除去相当量的Na +,而没有相应的水分流失,并且皮肤可以作为主要的盐储库。


近期,一项发表在杂志Hypertension上的研究数据显示,与血浆盐储存相比,皮肤是高渗的,这也适用于皮肤间质液。即使在血浆和间质液之间的小电解质梯度可以代表水肿产生力增强。

因为水积累是适度的,研究者们决定在大鼠中使用替代方法重新检查,在高盐饮食(8%NaCl和1%盐水饮料)或脱氧皮质酮颗粒植入诱导的盐积累期间组织液是否是高渗的。

这些治疗导致全身血压、皮肤盐和水积聚以及皮肤高渗性增加。然而,从植入的芯体分离的组织液和淋巴排泄是等渗的,并且通过离心和在淋巴中分离的流体中的Na +浓度与血浆没有不同。
有趣的是,通过洗脱皮肤层,从表皮到真皮存在渗透压和尿素梯度。

此项研究表明,以淋巴液方式离开皮肤的液体等离子体是等渗的,但是皮肤还可以通过产生在功能上可能具有重要的局部梯度来控制其自身的电解质微环境。

原始出处:
Nikpey E, Karlsen TV, Rakova N, et al. High-Salt Diet Causes Osmotic Gradients and Hyperosmolality in Skin Without Affecting Interstitial Fluid and Lymph. Hypertension. 2017 Feb 6. pii: HYPERTENSIONAHA.116.08539. 

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    2017-06-27 lq1776
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    2017-04-20 feather89
  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Feb 11 17:29:14 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629956, encodeId=36b51629956a8, content=<a href='/topic/show?id=cfc2102524b2' target=_blank style='color:#2F92EE;'>#高盐饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102524, encryptionId=cfc2102524b2, topicName=高盐饮食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded321409867, createdName=珙桐, createdTime=Sat Feb 11 12:15:00 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501114, encodeId=237c15011142f, content=<a href='/topic/show?id=f2db9238f9' target=_blank 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createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Feb 10 09:59:35 CST 2017, time=2017-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175342, encodeId=50d81e534258, content=所以,皮肤是很重要的, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Fri Feb 10 09:23:00 CST 2017, time=2017-02-10, status=1, ipAttribution=)]
    2017-02-11 ylzr123

    好文,值得点赞,值得拥有,值得收藏!

    0

  5. 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  6. 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  7. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175559, encodeId=56bd1e5559d8, content=保留或从体内除去相当量的Na+,而没有相应的水分流失, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Sat Feb 11 10:57:35 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175351, encodeId=77b71e535101, content=文章不错,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Feb 10 09:59:35 CST 2017, time=2017-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175342, encodeId=50d81e534258, content=所以,皮肤是很重要的, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Fri Feb 10 09:23:00 CST 2017, time=2017-02-10, status=1, ipAttribution=)]
    2017-02-11 cqykthl

    保留或从体内除去相当量的Na+,而没有相应的水分流失

    0

  8. 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    2017-02-11 cqykthl

    保留或从体内除去相当量的Na+,而没有相应的水分流失

    0

  9. 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createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Feb 10 09:59:35 CST 2017, time=2017-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175342, encodeId=50d81e534258, content=所以,皮肤是很重要的, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Fri Feb 10 09:23:00 CST 2017, time=2017-02-10, status=1, ipAttribution=)]
    2017-02-10 1e10c84am36(暂无匿称)

    文章不错,拜读了

    0

  10. 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style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Sat Feb 11 12:15:00 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175560, encodeId=70741e5560a6, content=保留或从体内除去相当量的Na+,而没有相应的水分流失, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Sat Feb 11 10:57:44 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175559, encodeId=56bd1e5559d8, content=保留或从体内除去相当量的Na+,而没有相应的水分流失, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Sat Feb 11 10:57:35 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175351, encodeId=77b71e535101, content=文章不错,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Feb 10 09:59:35 CST 2017, time=2017-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=175342, encodeId=50d81e534258, content=所以,皮肤是很重要的, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Fri Feb 10 09:23:00 CST 2017, time=2017-02-10, status=1, ipAttribution=)]
    2017-02-10 lyh994

    所以,皮肤是很重要的

    0

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