Asian Pac J Allergy Immunol:盐水洗鼻对儿童过敏性鼻炎和哮喘益处研究

2019-05-11 AlexYang MedSci原创

哮喘和过敏性鼻炎(AR)是气道慢性炎症疾病并且相互影响着疾病的严重度。最近,有研究人员调查了是否生理盐水洗鼻(NSI)能够改善哮喘和过敏性鼻炎(AR)儿童的气道高反应性和临床参数。研究人员招募了20名AR和哮喘儿童,年龄在6-18岁。患者被随机分成了2组:洗鼻组(8名男孩和2名女孩)和对照组(8名男孩和2名女孩)。洗鼻组每天都进行NSI。所有的参与者接受了为期12周的孟鲁司特,左西替利嗪,吸入糖皮

哮喘和过敏性鼻炎(AR)是气道慢性炎症疾病并且相互影响着疾病的严重度。最近,有研究人员调查了是否生理盐水洗鼻(NSI)能够改善哮喘和过敏性鼻炎(AR)儿童的气道高反应性和临床参数。

研究人员招募了20名AR和哮喘儿童,年龄在6-18岁。患者被随机分成了2组:洗鼻组(8名男孩和2名女孩)和对照组(8名男孩和2名女孩)。洗鼻组每天都进行NSI。所有的参与者接受了为期12周的孟鲁司特,左西替利嗪,吸入糖皮质激素治疗。研究发现,在洗鼻组中第12周时PC20要比基线测量值更高,而在对照组中,PC20在治疗前后没有显著差异(P = 0.333)。在洗鼻组中,ACT评分在12周的NSI治疗后增加(P = 0.007),而QQOL-ARK评分与基线评分相比减少(P = 0.028)。在对照组中,0周和12周的ACT和QQOL-ARK评分没有差异。另外,在洗鼻组和对照组中,PC20、ACT、QQOL-ARK和 FENO的均值变化均没有差异。

最后,研究人员指出,他们的结果表明了NSI对哮喘和AR儿童的治疗是有益的。

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    2019-12-03 luwei00
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    2019-11-22 TZF0804
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    2019-10-19 zutt
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    2019-05-13 膀胱癌