Histol Histopathol:海藻糖在眼科的重要作用

2019-01-19 MedSci MedSci原创

捷克科学院实验医学研究所的Cejka C和Kubinova S等人近日在Histol Histopathol杂志上发表了一篇综述论文,作者系统的阐述了海藻糖在眼科中的应用。

捷克科学院实验医学研究所的Cejka C和Kubinova S等人近日在Histol Histopathol杂志上发表了一篇综述论文,作者系统的阐述了海藻糖在眼科中的应用。

海藻糖是一种葡萄糖二糖,是一种天然存在的生物活性糖,无毒且没有还原性。当细胞暴露于包括脱水、热、氧化、甚至缺氧等压力条件下,海藻糖会被许多生物合成,。尽管海藻糖不是由哺乳动物细胞合成的,但最近已经证明海藻糖具有许多重要特性,这些特性表明它在人体中具有重要的用途。

海藻糖可以使细胞膜免受氧化损伤和干燥环境的影响,通过保护细胞,使伤口愈合。当用海藻糖治疗受伤的角膜时,会抑制角膜炎症、瘢痕形成和角膜新血管形成等。在干眼症中,海藻糖减少细胞凋亡并降低眼表面的氧化、炎症和蛋白水解活性。在UVB照射的角膜中,海藻糖抑制了由UVB射线引起的光损伤。它减少了角膜内炎症并减少角膜新生血管的形成。另外,海藻糖预防眼科手术后的术后纤维瘢痕形成。海藻糖的无毒性可以使其在人体中长期施用,并可以用于各种疾病状态。

原文出处:

Cejka, C., S. Kubinova, and J. Cejkova, Trehalose in ophthalmology. Histol Histopathol, 2019: p. 18082.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1703639, encodeId=a7e91e03639af, content=<a href='/topic/show?id=9b00886536' target=_blank style='color:#2F92EE;'>#HIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8865, encryptionId=9b00886536, topicName=HIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=133330532258, createdName=yuanming17, createdTime=Thu Jun 27 09:35:00 CST 2019, time=2019-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023535, encodeId=2cd520235359a, content=<a href='/topic/show?id=57ce9605ef6' target=_blank style='color:#2F92EE;'>#重要作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96057, encryptionId=57ce9605ef6, topicName=重要作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Wed May 08 03:35:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786235, encodeId=c16c1e8623531, content=<a href='/topic/show?id=569f13e9045' target=_blank style='color:#2F92EE;'>#Pathol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13790, encryptionId=569f13e9045, topicName=Pathol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b65161, createdName=yb6560, createdTime=Sun Sep 22 22:35:00 CST 2019, time=2019-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483913, encodeId=501a1483913bf, content=<a href='/topic/show?id=0c75656e370' target=_blank style='color:#2F92EE;'>#海藻糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65673, encryptionId=0c75656e370, topicName=海藻糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=372e7924972, createdName=12498cb5m15暂无昵称, createdTime=Mon Jan 21 04:35:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358650, encodeId=2f1d358650b0, content=这个很有前景, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2019/01/02/f667a67c6692f1e356c51a346d5b382f.jpg, createdBy=7b7a2515105, createdName=Janeinair, createdTime=Sat Jan 19 17:09:33 CST 2019, time=2019-01-19, status=1, ipAttribution=)]
    2019-06-27 yuanming17
  2. [GetPortalCommentsPageByObjectIdResponse(id=1703639, encodeId=a7e91e03639af, content=<a href='/topic/show?id=9b00886536' target=_blank style='color:#2F92EE;'>#HIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8865, encryptionId=9b00886536, topicName=HIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=133330532258, createdName=yuanming17, createdTime=Thu Jun 27 09:35:00 CST 2019, time=2019-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023535, encodeId=2cd520235359a, content=<a href='/topic/show?id=57ce9605ef6' target=_blank style='color:#2F92EE;'>#重要作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96057, encryptionId=57ce9605ef6, topicName=重要作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Wed May 08 03:35:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786235, encodeId=c16c1e8623531, content=<a href='/topic/show?id=569f13e9045' target=_blank style='color:#2F92EE;'>#Pathol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13790, encryptionId=569f13e9045, topicName=Pathol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b65161, createdName=yb6560, createdTime=Sun Sep 22 22:35:00 CST 2019, time=2019-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483913, encodeId=501a1483913bf, content=<a href='/topic/show?id=0c75656e370' target=_blank style='color:#2F92EE;'>#海藻糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65673, encryptionId=0c75656e370, topicName=海藻糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=372e7924972, createdName=12498cb5m15暂无昵称, createdTime=Mon Jan 21 04:35:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358650, encodeId=2f1d358650b0, content=这个很有前景, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2019/01/02/f667a67c6692f1e356c51a346d5b382f.jpg, createdBy=7b7a2515105, createdName=Janeinair, createdTime=Sat Jan 19 17:09:33 CST 2019, time=2019-01-19, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1703639, encodeId=a7e91e03639af, content=<a href='/topic/show?id=9b00886536' target=_blank style='color:#2F92EE;'>#HIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8865, encryptionId=9b00886536, topicName=HIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=133330532258, createdName=yuanming17, createdTime=Thu Jun 27 09:35:00 CST 2019, time=2019-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023535, encodeId=2cd520235359a, content=<a href='/topic/show?id=57ce9605ef6' target=_blank style='color:#2F92EE;'>#重要作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96057, encryptionId=57ce9605ef6, topicName=重要作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Wed May 08 03:35:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786235, encodeId=c16c1e8623531, content=<a href='/topic/show?id=569f13e9045' target=_blank style='color:#2F92EE;'>#Pathol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13790, encryptionId=569f13e9045, topicName=Pathol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b65161, createdName=yb6560, createdTime=Sun Sep 22 22:35:00 CST 2019, time=2019-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483913, encodeId=501a1483913bf, content=<a href='/topic/show?id=0c75656e370' target=_blank style='color:#2F92EE;'>#海藻糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65673, encryptionId=0c75656e370, topicName=海藻糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=372e7924972, createdName=12498cb5m15暂无昵称, createdTime=Mon Jan 21 04:35:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358650, encodeId=2f1d358650b0, content=这个很有前景, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2019/01/02/f667a67c6692f1e356c51a346d5b382f.jpg, createdBy=7b7a2515105, createdName=Janeinair, createdTime=Sat Jan 19 17:09:33 CST 2019, time=2019-01-19, status=1, ipAttribution=)]
    2019-09-22 yb6560
  4. [GetPortalCommentsPageByObjectIdResponse(id=1703639, encodeId=a7e91e03639af, content=<a href='/topic/show?id=9b00886536' target=_blank style='color:#2F92EE;'>#HIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8865, encryptionId=9b00886536, topicName=HIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=133330532258, createdName=yuanming17, createdTime=Thu Jun 27 09:35:00 CST 2019, time=2019-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023535, encodeId=2cd520235359a, content=<a href='/topic/show?id=57ce9605ef6' target=_blank style='color:#2F92EE;'>#重要作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96057, encryptionId=57ce9605ef6, topicName=重要作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Wed May 08 03:35:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786235, encodeId=c16c1e8623531, content=<a href='/topic/show?id=569f13e9045' target=_blank style='color:#2F92EE;'>#Pathol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13790, encryptionId=569f13e9045, topicName=Pathol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b65161, createdName=yb6560, createdTime=Sun Sep 22 22:35:00 CST 2019, time=2019-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483913, encodeId=501a1483913bf, content=<a href='/topic/show?id=0c75656e370' target=_blank style='color:#2F92EE;'>#海藻糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65673, encryptionId=0c75656e370, topicName=海藻糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=372e7924972, createdName=12498cb5m15暂无昵称, createdTime=Mon Jan 21 04:35:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358650, encodeId=2f1d358650b0, content=这个很有前景, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2019/01/02/f667a67c6692f1e356c51a346d5b382f.jpg, createdBy=7b7a2515105, createdName=Janeinair, createdTime=Sat Jan 19 17:09:33 CST 2019, time=2019-01-19, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1703639, encodeId=a7e91e03639af, content=<a href='/topic/show?id=9b00886536' target=_blank style='color:#2F92EE;'>#HIS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8865, encryptionId=9b00886536, topicName=HIS)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=133330532258, createdName=yuanming17, createdTime=Thu Jun 27 09:35:00 CST 2019, time=2019-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023535, encodeId=2cd520235359a, content=<a href='/topic/show?id=57ce9605ef6' target=_blank style='color:#2F92EE;'>#重要作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96057, encryptionId=57ce9605ef6, topicName=重要作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Wed May 08 03:35:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1786235, encodeId=c16c1e8623531, content=<a href='/topic/show?id=569f13e9045' target=_blank style='color:#2F92EE;'>#Pathol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13790, encryptionId=569f13e9045, topicName=Pathol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b65161, createdName=yb6560, createdTime=Sun Sep 22 22:35:00 CST 2019, time=2019-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483913, encodeId=501a1483913bf, content=<a href='/topic/show?id=0c75656e370' target=_blank style='color:#2F92EE;'>#海藻糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65673, encryptionId=0c75656e370, topicName=海藻糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=372e7924972, createdName=12498cb5m15暂无昵称, createdTime=Mon Jan 21 04:35:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358650, encodeId=2f1d358650b0, content=这个很有前景, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2019/01/02/f667a67c6692f1e356c51a346d5b382f.jpg, createdBy=7b7a2515105, createdName=Janeinair, createdTime=Sat Jan 19 17:09:33 CST 2019, time=2019-01-19, status=1, ipAttribution=)]
    2019-01-19 Janeinair

    这个很有前景

    0

相关资讯

Methods Mol Biol:斑马鱼眼外肌再生模型中的自噬作用综述

美国密歇根大学凯洛格眼科中心眼科学与视觉科学系的Saera-Vila A等研究人员,近日在Methods Mol Biol杂志上发表了一篇重要的综述论文。作者对手术肌肉损伤模型进行了详细的描述,对其用来研究自噬等实验方案也进行了讨论。

Cell重磅发布:2018年十大更佳论文/综述出炉

一年一度的Cell最佳系列终于出炉了。

Genes :Joubert综合征眼部症状综述

纽约州立大学下州医学中心的Wang SF和斯坦福大学医学院眼科的Kowal TJ等在Genes上发表了一篇综述,作者系统的回顾了在Joubert综合征患者中,目前已经发现的眼部表型。

Clin Ophthalmol:青少年和儿童阶段的葡萄膜黑色素瘤综述

美国俄亥俄州辛辛那提大学医学院眼科的Fry MV等人近日在Clin Ophthalmol杂志上发表了一篇重要的综述文章,作者对青少年和儿童阶段的葡萄膜黑色素瘤临床情况进行了综述。

Folia Med Cracov:维生素D在眼部疾病发病机制中的作用

Jagiellonian大学医学院病理生理学系的Skowron K等人近日在Folia Med Cracov杂志上发表了一篇综述文章,作者系统的总结了维生素D在眼部疾病发病机制中的作用。

Jpn J Ophthalmol:椎间盘出血对青光眼的影响

日本岐阜大学医学研究科眼科的Yamamoto T在Jpn J Ophthalmol杂志上发表了一篇重要的综述文章,从椎间盘出血研究方面讨论了临床对青光眼发生的理解。