Clin Transl Allergy:屋尘螨过敏性鼻炎患者的咽鼓管功能障碍

2020-08-11 AlexYang MedSci原创

鼻部炎症疾病是咽鼓管功能障碍(ETD)的一个重要病因。过敏性鼻炎(AR)在成年人中的患病率为10%到30%。然而,咽鼓管在AR患者中的情况研究仍旧有限。

鼻部炎症疾病是咽鼓管功能障碍(ETD)的一个重要病因。过敏性鼻炎(AR)在成年人中的患病率为10%到30%。然而,咽鼓管在AR患者中的情况研究仍旧有限。

鼻内镜评分代表性图片

研究是一个前瞻性的对照代表性研究,招募了59名志愿者和59名AR患者。研究发现,咽鼓管测压(TMM)检查结果表明22名AR患者(39只耳朵,33.1%)和5名健康对照(7只耳朵,5.9%)存在异常的咽鼓管压。22名AR患者(37.3%)和9名健康对照的ETDQ7评分≥15。考虑到AR患者的鼻症状,鼻塞的VAS评分与ETDQ-7评分相关,相关系数r=0.5124(p<0.0001)。鼻内镜评分也于ETDQ-7评分呈现正相关关系,相关系数为0.7328(p<0.0001)。1个月的治疗后,AR患者的鼻症状的VAS评分和ETDQ-7评分均显著减少(p<0.0001)。TMM检查同样表明了咽鼓管功能在治疗后明显改善(p<0.0001)。

鼻症状与HDM过敏性鼻炎患者咽鼓管功能内镜评分相关性

最后,研究人员指出,AR患者,尤其是那些具有严重鼻塞的患者很可能有ETD。咽鼓管咽口的局部情况与ETD的症状密切相关。在鼻腔糖皮质激素给药和口服抗组胺药物治疗后,咽鼓管功能明显改善,且鼻腔症状消退。

原始出处:

Yun Ma, Maojin Liang, Peng Tian et al. Eustachian tube dysfunction in patients with house dust mite-allergic rhinitis. Clin Transl Allergy. Jul 2020

 

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    2020-08-21 bsmagic9140
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    2020-08-13 膀胱癌
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    2020-08-11 Psycho.Dr Du

    我就是那10%…

    1

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