Medicine :臂丛神经阻滞,左布比卡因和罗哌卡因的术后镇痛效果并无差异

2017-05-06 MedSci MedSci原创

在药物的基础上,一般认为左布比卡因较罗哌卡因可持续更长的时间。然而,大多数报告臂丛阻滞时这两种麻醉剂在镇痛效果上并未存在明显的差异。本研究旨在对比左布比卡因和罗哌卡因用于治疗超声引导下臂丛神经阻滞术后的镇痛效果。 研究共纳入62名接受骨科手术的患者,随机接受左布比卡因( L组、n = 31)或罗哌卡因(R组,n = 31  )。记录患者术后镇痛持续时间、运动阻滞偏移时间、术后镇痛药用量及术后

在药物的基础上,一般认为左布比卡因较罗哌卡因可持续更长的时间。然而,大多数报告臂丛阻滞时这两种麻醉剂在镇痛效果上并未存在明显的差异。本研究旨在对比左布比卡因和罗哌卡因用于治疗超声引导下臂丛神经阻滞术后的镇痛效果。

研究共纳入62名接受骨科手术的患者,随机接受左布比卡因( L组、n = 31)或罗哌卡因(R组,n = 31  )。记录患者术后镇痛持续时间、运动阻滞偏移时间、术后镇痛药用量及术后睡眠障碍。记录手术当天,术后第1天和第2天的疼痛评分。

在需要镇痛药物前的时间间隔方面两组并未存在差异(L组:15.6 [ 11.4,16.8 ]小时;R组:12.5 [ 9.4,16 ]小时,P  = 0.32)。在运动阻滞持续时间(L组:12.2 [ 7.6,14.4 ]小时;R组:9.4 [ 7.9,13.2 ]小时,P = 0.44)、疼痛评分(P = 0.92  ),对镇痛药的需要(L组: 55%;R组:65%,P = 0.6),  睡眠障碍的发生率(L组:61%,R组:58%,P = 1  )方面两组也无明显差异。

总而言之,该研究发现,在用于臂丛神经阻滞时,左布比卡因和罗哌卡因的术后镇痛效果并没有差异。

原始出处:

Watanabe K, Tokumine J, et al.,Postoperative analgesia comparing levobupivacaine and ropivacaine for brachial plexus block: A randomized prospective trial. Medicine (Baltimore). 2017 Mar;96(12):e6457. doi: 10.1097/MD.0000000000006457.

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    2017-05-30 kalseyzl
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    2018-02-01 jeanqiuqiu
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    2017-05-15 lou.minghong

    学习

    0

  5. 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    2017-05-08 zhaojie88
  6. 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  7. 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