NEJM:气肿性肾盂肾炎-案例报道

2016-10-28 MedSci MedSci原创

患者男性,51岁,出现发热和不适感持续2周余。据该患者自述,其20年前确诊患有糖尿病,但一直以来血糖控制不佳。入院时,其实验室检查的结果显示,白细胞计数为10800/mm3(正常范围,3900至9800);C反应蛋白水平为8.6mg/dl;血尿素氮90mg/dl;肌酐4.9mg/dl和糖化血红蛋白水平为11.2%。腹部X线平片(图A)和计算机断层扫描(图B)显示左肾的肾实质和肾周间隙可见气肿现象。

患者男性,51岁,出现发热和全身不适感持续2周余。



据该患者自述,其20年前确诊患有糖尿病,但一直以来血糖控制不佳。

入院时,其实验室检查的结果显示,白细胞计数为10800/mm3(正常范围,3900-9800);C反应蛋白水平为8.6mg/dL;血尿素氮90mg/dl(32 mmol/L));肌酐4.9mg/dl(430 μmol/L);糖化血红蛋白水平为11.2%。

腹部X线平片(图A)和计算机断层扫描(图B)显示左肾的肾实质和肾周间隙可见气肿现象。

此外,在血培养中发现了大肠杆菌的存在,而尿培养并未发现。

根据以上的临床症状及检查结果,最后该患者被诊断为气肿性肾盂肾炎。而其发病的原因很有可能是由于糖尿病神经源性膀胱炎逆行感染引起的。

最后,该患者接受抗生素治疗,感染很快得到了控制,且肾功能明显有所好转(血尿素氮水平降至23mg/dL[8 mmol/L],肌酐降至2.6ml/dL[230 μmol/L]))。

原始出处:

Yasumitsu Hirose, M.D.Hayato Kaida, M.D. Emphysematous Pyelonephritis.N Engl J Med 2016; 375:1671October 27, 2016

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    2016-10-30 villahu
  2. [GetPortalCommentsPageByObjectIdResponse(id=1532210, encodeId=91ec153221022, content=<a href='/topic/show?id=10b5825e4aa' target=_blank style='color:#2F92EE;'>#肾炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82574, encryptionId=10b5825e4aa, topicName=肾炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84df12331144, createdName=villahu, createdTime=Sun Oct 30 03:11:00 CST 2016, time=2016-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151891, encodeId=a4bf151891ad, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Sat Oct 29 10:54:54 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151853, encodeId=22f0151853cc, content=学习了,这个很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4BGdu4COj6QWFqgMd3xnWDdgLZKUGI32veZvO2qFAQvpYr1eMbUOTqMvlZWc3MsugtFMHzxDwial/0, createdBy=88731939304, createdName=圣艮山, createdTime=Sat Oct 29 08:33:24 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151806, encodeId=79661518060d, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Oct 29 00:52:21 CST 2016, time=2016-10-29, status=1, ipAttribution=)]
    2016-10-29 xyfg98

    谢谢分享!

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1532210, encodeId=91ec153221022, content=<a href='/topic/show?id=10b5825e4aa' target=_blank style='color:#2F92EE;'>#肾炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82574, encryptionId=10b5825e4aa, topicName=肾炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84df12331144, createdName=villahu, createdTime=Sun Oct 30 03:11:00 CST 2016, time=2016-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151891, encodeId=a4bf151891ad, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Sat Oct 29 10:54:54 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151853, encodeId=22f0151853cc, content=学习了,这个很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4BGdu4COj6QWFqgMd3xnWDdgLZKUGI32veZvO2qFAQvpYr1eMbUOTqMvlZWc3MsugtFMHzxDwial/0, createdBy=88731939304, createdName=圣艮山, createdTime=Sat Oct 29 08:33:24 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151806, encodeId=79661518060d, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Oct 29 00:52:21 CST 2016, time=2016-10-29, status=1, ipAttribution=)]
    2016-10-29 圣艮山

    学习了,这个很不错

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1532210, encodeId=91ec153221022, content=<a href='/topic/show?id=10b5825e4aa' target=_blank style='color:#2F92EE;'>#肾炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82574, encryptionId=10b5825e4aa, topicName=肾炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=84df12331144, createdName=villahu, createdTime=Sun Oct 30 03:11:00 CST 2016, time=2016-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151891, encodeId=a4bf151891ad, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Sat Oct 29 10:54:54 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151853, encodeId=22f0151853cc, content=学习了,这个很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4BGdu4COj6QWFqgMd3xnWDdgLZKUGI32veZvO2qFAQvpYr1eMbUOTqMvlZWc3MsugtFMHzxDwial/0, createdBy=88731939304, createdName=圣艮山, createdTime=Sat Oct 29 08:33:24 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=151806, encodeId=79661518060d, content=继续努力, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Oct 29 00:52:21 CST 2016, time=2016-10-29, status=1, ipAttribution=)]
    2016-10-29 忠诚向上

    继续努力

    0

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