Lancet Public Health:虚弱与新冠肺炎患者不良预后

2020-07-01 MedSci原创 MedSci原创

相比于年龄和共病,虚弱评分可更好的预测新冠肺炎住院患者不良预后风险

COVID-19大流行给卫生保健系统带来了前所未有的压力,虚弱是许多疾病不良预后的重要因素,COPE研究中,研究人员评估了COVID-19患者入院虚弱与死亡率和住院时间的关系。
 
这是一项观察性队列研究,在英国的10家医院和意大利的1家医院进行。所有因新型冠状病毒肺炎入院的成年人(≥18岁)患者参与研究,排除住院记录不完整的患者。脆弱程度由COVID-19专家团队使用临床虚弱评估表(CFS)进行评估,并根据他们的评分对患者进行分层(1-2分为适当;3-4分为脆弱,但不虚弱;5-6为出现虚弱迹象,但具有一定自理能力;7-9分为严重或非常严重的虚弱)。研究的主要结果是住院死亡率。
 
总计1564名COVID-19患者参与研究,中位年龄为74岁,903(57.7%)名男性,661(42.3%)名女性;425人(27.2%)在数据截止时死亡(2020年4月28日)。772例(49.4%)被划分为虚弱(CFS 5-8),27例(1.7%)被划分为病危(CFS9)。与CFS 1-2分患者相比,CFS 3-4分患者从入院到死亡时间的调整风险比为1.55,CFS 5-6为1.83,CFS 7-9为2.39,入院7天死亡风险比为CFS 3-4为1.22,CFS 5-6为1.62CFS 7-9为3.12。
 
研究认为,相比于年龄和共病,虚弱评分可更好的预测新冠肺炎住院患者不良预后风险。
 
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    2020-09-20 howi
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    2020-10-26 145df198m92暂无昵称

    学习

    0

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    2020-08-27 14818eb4m67暂无昵称

    学习了

    0

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    2020-10-01 shizhenshan
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    2020-07-02 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

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    2020-07-02 wxl882001

    了解一下

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1830723, encodeId=104d1830e232b, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Sep 20 00:56:16 CST 2020, time=2020-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=894470, encodeId=09fc8944e0dc, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5fa45094814, createdName=145df198m92暂无昵称, createdTime=Mon Oct 26 08:25:20 CST 2020, time=2020-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813690, encodeId=aaa9813690cc, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 07:52:26 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861386, encodeId=61b218613865a, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Thu Oct 01 11:56:16 CST 2020, time=2020-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336415, encodeId=9d1a133641510, content=<a href='/topic/show?id=071820530c5' target=_blank style='color:#2F92EE;'>#不良预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20530, encryptionId=071820530c5, topicName=不良预后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c97a2500111, createdName=thinkibmz_44722594, createdTime=Fri Jul 03 09:56:16 CST 2020, time=2020-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621856, encodeId=e72d1621856a6, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Fri Jul 03 09:56:16 CST 2020, time=2020-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800975, encodeId=1ccc8009e5f8, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 02 22:35:06 CST 2020, time=2020-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800853, encodeId=6d978008539d, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu Jul 02 07:25:15 CST 2020, time=2020-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800837, encodeId=87f180083e0f, content=确实, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Wed Jul 01 23:14:41 CST 2020, time=2020-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028241, encodeId=53d8102824137, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Wed Jul 01 21:56:16 CST 2020, time=2020-07-01, status=1, ipAttribution=)]
    2020-07-01 神盾医疗局局长Jack

    确实

    0

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    2020-07-01 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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