J Endod:未发育成熟恒牙牙髓再生后的临床和分子微生物评估

2020-08-12 lishiting MedSci原创

这篇研究的目的是通过分子微生物的方法评估牙髓再生后细菌水平以及它们与治疗效果的关联。

这篇研究的目的是通过分子微生物的方法评估牙髓再生后细菌水平以及它们与治疗效果的关联。

研究通过qPCR分析15例牙髓坏死的未发育成熟恒牙的根管样本。在治疗前(S1)、6% NaOCl冲洗后(S2)以及根管内采用三联抗菌糊剂(TAP) (n = 7)或氯己定(CHP)伴随氢氧化钙(n = 8)封药后(S3)进行细菌计数。对相关样本采用Wilcoxon检验以及Mann-Whitney检验进行统计学分析(p < 0.05)。随访12-48个月后,采用线性回归模型分析临床和放射线结果与微生物数据的相关性(p < 0.05)。

结果显示,所有S1和S2样本的细菌呈阳性,但是阳性S3样本的数量减至53.3% (p = 0.001)。总体上说,每个治疗步骤后的细菌水平均明显降低(S1-S2, p = 0.001; S2-S3, p = 0.02)。在TAP和CHP组,S3样本阳性比例分别为57.1%和50%,细菌中位数分别为6.97 x 103和3.59 x 104。组间未见显著性差异。即使存在较低水平的残留细菌,所有病例根尖均已愈合。然而,残留细菌对牙本质壁的厚度存在负面影响(R2 = 0.0043)。

结论:尽管牙髓再生后细菌水平明显降低,但残存细菌影响着牙本质壁的厚度。

原始出处:

Adriana de-Jesus-Soares, Marina C Prado, et al. Clinical and Molecular Microbiological Evaluation of Regenerative Endodontic Procedures in Immature Permanent Teeth. J Endod., 2020 Jul 15;S0099-2399(20)30492-1. doi: 10.1016/j.joen.2020.07.005.

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1669877, encodeId=36bd16698e74b, content=<a href='/topic/show?id=c7ca6e660ab' target=_blank style='color:#2F92EE;'>#牙髓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67660, encryptionId=c7ca6e660ab, topicName=牙髓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sun May 09 04:59:03 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825191, encodeId=a57c18251916b, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Jun 04 18:59:03 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347500, encodeId=2540134e500ba, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417534, encodeId=bd36141e53449, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601271, encodeId=bace16012e1cb, content=<a href='/topic/show?id=eb1b5282260' target=_blank style='color:#2F92EE;'>#恒牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52822, encryptionId=eb1b5282260, topicName=恒牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27f418863982, createdName=zhaozuguo, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808461, encodeId=a49580846149, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=ms 内分泌科张, createdTime=Thu Aug 13 17:09:31 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2021-05-09 jxrzshh
  2. [GetPortalCommentsPageByObjectIdResponse(id=1669877, encodeId=36bd16698e74b, content=<a href='/topic/show?id=c7ca6e660ab' target=_blank style='color:#2F92EE;'>#牙髓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67660, encryptionId=c7ca6e660ab, topicName=牙髓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sun May 09 04:59:03 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825191, encodeId=a57c18251916b, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Jun 04 18:59:03 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347500, encodeId=2540134e500ba, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417534, encodeId=bd36141e53449, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601271, encodeId=bace16012e1cb, content=<a href='/topic/show?id=eb1b5282260' target=_blank style='color:#2F92EE;'>#恒牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52822, encryptionId=eb1b5282260, topicName=恒牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27f418863982, createdName=zhaozuguo, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808461, encodeId=a49580846149, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=ms 内分泌科张, createdTime=Thu Aug 13 17:09:31 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1669877, encodeId=36bd16698e74b, content=<a href='/topic/show?id=c7ca6e660ab' target=_blank style='color:#2F92EE;'>#牙髓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67660, encryptionId=c7ca6e660ab, topicName=牙髓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sun May 09 04:59:03 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825191, encodeId=a57c18251916b, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Jun 04 18:59:03 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347500, encodeId=2540134e500ba, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417534, encodeId=bd36141e53449, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601271, encodeId=bace16012e1cb, content=<a href='/topic/show?id=eb1b5282260' target=_blank style='color:#2F92EE;'>#恒牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52822, encryptionId=eb1b5282260, topicName=恒牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27f418863982, createdName=zhaozuguo, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808461, encodeId=a49580846149, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=ms 内分泌科张, createdTime=Thu Aug 13 17:09:31 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2020-08-14 neurowu
  4. [GetPortalCommentsPageByObjectIdResponse(id=1669877, encodeId=36bd16698e74b, content=<a href='/topic/show?id=c7ca6e660ab' target=_blank style='color:#2F92EE;'>#牙髓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67660, encryptionId=c7ca6e660ab, topicName=牙髓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sun May 09 04:59:03 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825191, encodeId=a57c18251916b, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Jun 04 18:59:03 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347500, encodeId=2540134e500ba, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417534, encodeId=bd36141e53449, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601271, encodeId=bace16012e1cb, content=<a href='/topic/show?id=eb1b5282260' target=_blank style='color:#2F92EE;'>#恒牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52822, encryptionId=eb1b5282260, topicName=恒牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27f418863982, createdName=zhaozuguo, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808461, encodeId=a49580846149, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=ms 内分泌科张, createdTime=Thu Aug 13 17:09:31 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1669877, encodeId=36bd16698e74b, content=<a href='/topic/show?id=c7ca6e660ab' target=_blank style='color:#2F92EE;'>#牙髓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67660, encryptionId=c7ca6e660ab, topicName=牙髓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sun May 09 04:59:03 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825191, encodeId=a57c18251916b, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Jun 04 18:59:03 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347500, encodeId=2540134e500ba, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417534, encodeId=bd36141e53449, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601271, encodeId=bace16012e1cb, content=<a href='/topic/show?id=eb1b5282260' target=_blank style='color:#2F92EE;'>#恒牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52822, encryptionId=eb1b5282260, topicName=恒牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27f418863982, createdName=zhaozuguo, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808461, encodeId=a49580846149, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=ms 内分泌科张, createdTime=Thu Aug 13 17:09:31 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2020-08-14 zhaozuguo
  6. [GetPortalCommentsPageByObjectIdResponse(id=1669877, encodeId=36bd16698e74b, content=<a href='/topic/show?id=c7ca6e660ab' target=_blank style='color:#2F92EE;'>#牙髓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67660, encryptionId=c7ca6e660ab, topicName=牙髓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5eeb26562774, createdName=jxrzshh, createdTime=Sun May 09 04:59:03 CST 2021, time=2021-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1825191, encodeId=a57c18251916b, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Jun 04 18:59:03 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347500, encodeId=2540134e500ba, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417534, encodeId=bd36141e53449, content=<a href='/topic/show?id=84ff6e663c4' target=_blank style='color:#2F92EE;'>#牙髓再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67663, encryptionId=84ff6e663c4, topicName=牙髓再生)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cf73291723, createdName=zhixianchen, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601271, encodeId=bace16012e1cb, content=<a href='/topic/show?id=eb1b5282260' target=_blank style='color:#2F92EE;'>#恒牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52822, encryptionId=eb1b5282260, topicName=恒牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27f418863982, createdName=zhaozuguo, createdTime=Fri Aug 14 11:59:03 CST 2020, time=2020-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=808461, encodeId=a49580846149, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201214/b3170121d995432ea306ae3a7809cc05/2cfb236f361b4d3c80ef8fdef4301832.jpg, createdBy=8ad35400531, createdName=ms 内分泌科张, createdTime=Thu Aug 13 17:09:31 CST 2020, time=2020-08-13, status=1, ipAttribution=)]
    2020-08-13 ms 内分泌科张

    学习

    0

相关资讯

Sci Rep:恶性前列腺癌中,SFRP4基因表达增加

为了改善危险分层和治疗选择,惰性前列腺癌和恶性前列腺癌之间的分子差异更多的了解是需要的。分泌性卷曲相关蛋白4(SFRP4)是癌症相关的Wnt信号通路的调控子,并且之前有报道它可作为前列腺癌恶化的一个潜在的标记。最近,有研究人员调查和确定了在9个独立群体中,SFRP4基因表达与恶化之间的关系(n=2157)。研究人员通过对所有群体的差异表达和组合元分析,检测到了SFRP4在癌症中要比正常样本中表达量

J Endod:髓石和肾结石之间的联系:一项meta分析和系统性文献回顾

这是一篇分析和评估髓石和肾结石之间联系的系统性文献回顾及meta分析。

J Clin Periodontol:HFE血色病患者的牙周病程度和血清生物标记物水平的关联性研究:一项系列病例分析

这篇研究的目的是为了探讨HFE血色病患者中血清标记物和牙周病程度之间的联系。

BMJ:英国研究揭示备受争议的“深加工”食品与癌症之间关系的真相!

《英国医学杂志》(BMJ)今天发表的一项研究报告说,饮食中摄入深加工食物与癌症之间可能存在关联。

J Endod:牙髓病发状态与心血管疾病的潜在联系

根尖周炎(AP)和心血管疾病(CVDs)均为炎症反应触发的慢性致病过程,它们具有相似的致病机制和分子组成。有研究显示,AP可能使全身性的炎症状态持续存在,进而促进CVD的发生。这篇研究的目的是通过流行病学及基因组学方法评估牙髓致病状态与CVD之间的潜在联系。

J Periodontal Res:口腔炎症负载:口腔健康的标志物-中性粒细胞

由于发病率较高以及对系统疾病具有争论的有害作用,牙周疾病成为卫生保健系统的一项重大挑战。目前诊断牙周疾病的方法仅单纯的采用临床标准。这些方法不够精确,并且多少存在一定的侵入性。因此,很有必要研发一种非