Acta Biomed:抽烟对过敏性鼻炎的影响研究

2019-08-02 AlexYang MedSci原创

之前研究表明,接触烟草烟雾能够恶化过敏性鼻炎的症状。另外,一些研究也阐释了烟草烟雾与过敏性鼻炎(AR)的负相关关系。最近,有研究人员针对上述结论的不一致性,评估了抽烟和不抽烟的AR患者中,生活质量和免疫炎症参数情况。研究人员进行的是一个代表性的比较研究,包括了2个组:基于唾液可替宁测量的抽烟组和不抽烟组。每个组包括了22名AR患者,且他们的人口统计学特性没有显著差异。研究发现,在AR抽烟组中,与A

之前研究表明,接触烟草烟雾能够恶化过敏性鼻炎的症状。另外,一些研究也阐释了烟草烟雾与过敏性鼻炎(AR)的负相关关系。

最近,有研究人员针对上述结论的不一致性,评估了抽烟和不抽烟的AR患者中,生活质量和免疫炎症参数情况。研究人员进行的是一个代表性的比较研究,包括了2个组:基于唾液可替宁测量的抽烟组和不抽烟组。每个组包括了22名AR患者,且他们的人口统计学特性没有显著差异。研究发现,在AR抽烟组中,与AR不抽烟组比较唾液可替宁水平(p<0.001)显著更高,肺功能FEV1(p=0.044) 和FEV1/FVC (p=0.047) 均显著更低。血清IL-33在2个小组中具有显著的差异(P<0.001),即抽烟者比不抽烟者具有更高的值。另外,2个组之间的MiniRQLQ没有显著的差异。尽管烟草烟雾与更严重的症状没有相关性,但是抽烟与AR患者中气道重塑风险的增加和肺功能的减弱相关。因此,当抽烟不可避免时,合适的治疗是需要的。

原始出处:

Grillo C, La Mantia I, Grillo CM et al. Influence of cigarette smoking on allergic rhinitis: a comparative study on smokers and non-smokers. Acta Biomed. 10 Jul 2019

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    2019-09-12 windight
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    2019-11-06 sunylz
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    2019-08-04 gujh
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