Neurology:HIV相关脑血管病伴随多发动脉瘤一例

2017-10-07 杨中华 脑血管病及重症文献导读

在儿童,HIV相关脑血管病伴随多发动脉瘤已经被广泛报道。对于成人HIV患者,如果脑脊液中病毒负荷量较高,也应该考虑与HIV有关。典型影像学表现为结节和梭型动脉瘤,其病因可能与自身免疫有关,容易和结节性多动脉炎混淆。这些动脉瘤可以引起蛛网膜下腔出血,也可以由于血栓形成导致脑梗死。高效抗逆转录病毒疗法是有效的。

女性,40岁。缺血性卒中,脑脊液HIV病毒含量高(380000/ml)。MRI显示豆纹动脉和较大的脑动脉周围支多发性动脉瘤(图A和B):





DSA进一步确认了动脉瘤(图C和D):





经过13个月治疗,大部分动脉瘤体积变小(图E和F):





儿童,HIV相关脑血管病伴随多发动脉瘤已经被广泛报道。对于成人HIV患者,如果脑脊液中病毒负荷量较高,也应该考虑与HIV有关。典型影像学表现为结节和梭型动脉瘤,其病因可能与自身免疫有关,容易和结节性多动脉炎混淆。这些动脉瘤可以引起蛛网膜下腔出血,也可以由于血栓形成导致脑梗死。高效抗逆转录病毒疗法是有效的。

原始出处:
Seiler A, You SJ, Wagner M, et al. Teaching NeuroImages: HIV-associated cerebral vasculopathy with multiple nodular aneurysms. Neurology. 2017 Apr 4;88(14):e143-e144

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    2017-11-02 yinhl1978
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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Mon Oct 09 08:31:46 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251344, encodeId=2c8325134446, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Oct 08 09:58:29 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251339, encodeId=2cbf25133910, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Oct 08 09:33:04 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251310, encodeId=6e3c2513102d, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=353a2047758, createdName=137****9095, createdTime=Sun Oct 08 09:00:41 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251262, encodeId=4df925126264, content=好好努力学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Oct 08 07:08:43 CST 2017, time=2017-10-08, status=1, ipAttribution=)]
    2017-10-13 lucycici

    学习了

    0

  5. 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attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Oct 08 09:33:04 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251310, encodeId=6e3c2513102d, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=353a2047758, createdName=137****9095, createdTime=Sun Oct 08 09:00:41 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251262, encodeId=4df925126264, content=好好努力学习, beContent=null, objectType=article, channel=null, level=null, 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    2017-10-09 changjiu

    学习了.谢谢

    0

  6. 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likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Oct 08 07:08:43 CST 2017, time=2017-10-08, status=1, ipAttribution=)]
    2017-10-09 Drhzm308

    谢谢.学习了

    0

  7. 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likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Oct 08 07:08:43 CST 2017, time=2017-10-08, status=1, ipAttribution=)]
    2017-10-08 131****1460

    学习了受益匪浅

    0

  8. 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likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Oct 08 07:08:43 CST 2017, time=2017-10-08, status=1, ipAttribution=)]
    2017-10-08 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

  9. 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    2017-10-08 137****9095

    henhao

    0

  10. 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    2017-10-08 忠诚向上

    好好努力学习

    0

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