BMC Cancer:会阴部肿瘤切除术后,植入皮瓣的结局观察

2015-11-08 Seven L 译 MedSci原创

对会阴部癌症患者进行皮瓣重建,术后患者的结局和生活质量如何没有数据调查。研究者进行了一项研究评估晚期或复发性会阴部恶性肿瘤患者性行肌皮/皮肤皮瓣植入后的结局。该研究共纳入36名患者,其中 58.33 %的患者使用股前外侧皮瓣 (ALT),16.67 %的患者使用阴股沟皮瓣(PTF),11.11 %的患者使用腹壁下动脉穿支皮瓣 (DIEP),2.78 %的患者使用股薄肌肌皮瓣, 11.11 %的患者

对会阴部癌症患者进行皮瓣重建,术后患者的结局和生活质量如何没有数据调查。研究者进行了一项研究评估晚期或复发性会阴部恶性肿瘤患者性行肌皮/皮肤皮瓣植入后的结局。

该研究共纳入36名患者,其中 58.33 %的患者使用股前外侧皮瓣 (ALT),16.67 %的患者使用阴股沟皮瓣(PTF),11.11 %的患者使用腹壁下动脉穿支皮瓣 (DIEP),2.78 %的患者使用股薄肌肌皮瓣, 11.11 %的患者使用了2种皮瓣。

研究数据显示,11名(30.56%)患者出现了并发症,5名 (13.89 %)患者出现局部坏死,5名(13.89 %)患者出现了小的伤口裂开,1名(2.78 %)患者出现了皮瓣蜂窝织炎。局部坏死患者全部进行了再次手术。重建手术前后患者的平均口头评价得分分别为1.44和0.17(P < 0.0001)。平均性能状态手术前后分别为1.67和0.31,得到改善(P < 0.0001)。术后中位数随访时间9个月。重建术后21名(58.3 %)患者在间隔中位数5个月后出现了复发。中位数随访14个月后,41.7%的患者无疾病存活。纳入研究的36名患者的5年生存率为53.8%。

研究结果表明,对晚期/复发会阴部恶性肿瘤切除患者,进行软组织重建可降低术后并发症、减少疼痛、改善功能。尽管该人群的复发率依旧很高,不过重建对其仍有益。

原始出处:

Zhang W, Zeng A,et al.Outcome of vulvar reconstruction in patients with advanced and recurrent vulvar malignancies.BMC Cancer. 2015 Nov 5;15(1):851.

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    2015-11-10 sunylz
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    2015-11-10 jiyangfei

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癌症的早期筛查、诊断和治疗非常重要,有关专家指出,肺癌、胃癌、结直肠癌、肝癌、食管癌是我国发病率排名前五的恶性肿瘤,它们的共同特点是早期治疗效果好,较理想,到了中晚期转移复发概率高,因此抗癌的关键是早期筛查、诊断及治疗。  肺癌筛查方法:建议每年做一次低剂量CT筛查肺癌,如果CT发现肺部有阴影或小结,特别是磨玻璃样的阴影和小结,最好到正规大医院找有经验的医生看看,有必要的话可以做个病理活检。高危对

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