Neurology:儿童海绵窦血栓——病例研究及文献综述

2015-12-31 phylis 译 MedSci原创

目的:描述一个单中心队列研究的12例儿童海绵窦血栓患者的临床特点、影像学表现、发病率及死亡率,并对所有语言为英语的病例进行回顾性分析。方法:回顾性分析我院12例患者的临床资料及影像学资料。进行文献检索和审查,并与新的队列进行汇总分析。结果:回顾性分析2000年1月1日至2013年12月31日,费城儿童医院海绵窦血栓形成的患者十二例。所有患者均存活出院,3/12(25%)为神经系统的发病。对比增强M

目的:描述一个单中心队列研究的12例儿童海绵窦血栓患者的临床特点、影像学表现、发病率及死亡率,并对所有语言为英语的病例进行回顾性分析。

方法:回顾性分析我院12例患者的临床资料及影像学资料。进行文献检索和审查,并与新的队列进行汇总分析。

结果:回顾性分析2000年1月1日至2013年12月31日,费城儿童医院海绵窦血栓形成的患者十二例。所有患者均存活出院,3/12(25%)为神经系统的发病。对比增强MRI及增强CT检测海绵窦血栓敏感性为100%,而TOF MRV与平扫头颅CT敏感性为0%。文献综述40例患者,总死亡率为4/52(8%),发病率为10/40(25%)。单侧与双侧海绵窦受累的患者,通过治疗不能改变预后。真菌感染,预后不良。

结论:研究者的病例系列显示通过早期,积极的外科手术,抗菌及抗凝治疗,患者发病率及死亡率较低。尽管抗凝和手术与不同预后不相关,需要进一步的研究。

原文出处:

Smith DM, Vossough A, et al. Pediatric cavernous sinus thrombosis: A case series and review of the literature. Neurology. 2015 Sep 1.


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    2016-08-13 yinhl1978
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    2016-01-24 1de3b290m83(暂无匿称)

    不明头痛患儿注意排查

    0

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    2016-01-13 丁丁医生2002

    我来学习了

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    2015-12-31 忠诚向上

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