进展

订阅

MedSci主页 / 所有栏目 / 进展

Infect Dis ：镰状细胞病成人患者非伤寒沙门氏菌感染的严重非特异性症状

2018-11-04 MedSci MedSci原创

关注

非伤寒沙门氏菌病（NTS）常会感染镰状细胞病（SCD）的儿童，并且仍然是大致发展中国家人群死亡的重要原因。然而，目前缺乏有关SCD成人NTS的临床表现、结果和并发症的报道。 本研究2006年至2016年间对3名转诊中心诊断为NTS的成人SCD进行了图表审查，监测了大约3500名SCD成人。 结果，在22名SCD成人中诊断出23种NTS。诊断结果十分危险：65％（n = 15/23）患者

非伤寒沙门氏菌病（NTS）常会感染镰状细胞病（SCD）的儿童，并且仍然是大致发展中国家人群死亡的重要原因。然而，目前缺乏有关SCD成人NTS的临床表现、结果和并发症的报道。

本研究2006年至2016年间对3名转诊中心诊断为NTS的成人SCD进行了图表审查，监测了大约3500名SCD成人。

结果，在22名SCD成人中诊断出23种NTS。诊断结果十分危险：65％（n = 15/23）患者出现血管闭塞性危象（VOC），30％无发热。分离的血清型是：ser。肠炎沙门氏菌（n = 8），ser。鼠伤寒沙门氏菌（n = 6），其他（n = 3）。我们确定了两种感染模式：（1）菌血症NTS（n = 15），有（n = 9）或没有（n = 6）继发感染灶；（2）具有感染性肠外病灶的非菌血性NTS（n = 8），包括原发性骨/关节感染（n = 5）。半骨关节局限性患者（n = 6/13）在同一部位有骨坏死（n = 2）或骨髓炎（n = 4）的既往史。发病率很高，6名患者（26％）入住重症监护室，14名患者（61％）需要输注红细胞以进行VOC。一半的发作患者（n = 12）需要手术（n = 10）或介入放射学（n = 2）来控制感染。一名患者在第一次发作后一年出现NTS菌血症复发。

总之，除了血感染外，STS成人的NTS临床表现在入院时是非特异性的。在30％的病例中观察到包括菌血症，继发性感染灶和骨定位的三联体。

原始出处：

Guery R, Habibi A, et al., Severe, non specific symptoms in non-typhoidal Salmonella infections in adult patients with sickle cell disease: a retrospective multicentre study. Infect Dis (Lond). 2018 Oct 14:1-9. doi: 10.1080/23744235.2018.1500706.

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1899250, encodeId=5895189925088, content=<a href='/topic/show?id=6f746e94170' target=_blank style='color:#2F92EE;'>#特异性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67941, encryptionId=6f746e94170, topicName=特异性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Jun 25 13:07:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739834, encodeId=5a411e39834ec, content=<a href='/topic/show?id=ed7126020e0' target=_blank style='color:#2F92EE;'>#伤寒沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26020, encryptionId=ed7126020e0, topicName=伤寒沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c9cd34575980, createdName=zywlvao, createdTime=Thu Sep 19 15:07:00 CST 2019, time=2019-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012851, encodeId=5caf201285126, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Sep 24 12:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399149, encodeId=700b13991495d, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615496, encodeId=946816154960e, content=<a href='/topic/show?id=280196865f7' target=_blank style='color:#2F92EE;'>#镰状细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96865, encryptionId=280196865f7, topicName=镰状细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb4819654385, createdName=1508842480_96220443, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351546, encodeId=a49a351546cb, content=学习了，涨知识了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Nov 04 20:22:03 CST 2018, time=2018-11-04, status=1, ipAttribution=)]
    2019-06-25 jinweidong

    #特异性#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1899250, encodeId=5895189925088, content=<a href='/topic/show?id=6f746e94170' target=_blank style='color:#2F92EE;'>#特异性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67941, encryptionId=6f746e94170, topicName=特异性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Jun 25 13:07:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739834, encodeId=5a411e39834ec, content=<a href='/topic/show?id=ed7126020e0' target=_blank style='color:#2F92EE;'>#伤寒沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26020, encryptionId=ed7126020e0, topicName=伤寒沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c9cd34575980, createdName=zywlvao, createdTime=Thu Sep 19 15:07:00 CST 2019, time=2019-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012851, encodeId=5caf201285126, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Sep 24 12:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399149, encodeId=700b13991495d, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615496, encodeId=946816154960e, content=<a href='/topic/show?id=280196865f7' target=_blank style='color:#2F92EE;'>#镰状细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96865, encryptionId=280196865f7, topicName=镰状细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb4819654385, createdName=1508842480_96220443, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351546, encodeId=a49a351546cb, content=学习了，涨知识了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Nov 04 20:22:03 CST 2018, time=2018-11-04, status=1, ipAttribution=)]
    2019-09-19 zywlvao

    #伤寒沙门氏菌#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1899250, encodeId=5895189925088, content=<a href='/topic/show?id=6f746e94170' target=_blank style='color:#2F92EE;'>#特异性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67941, encryptionId=6f746e94170, topicName=特异性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Jun 25 13:07:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739834, encodeId=5a411e39834ec, content=<a href='/topic/show?id=ed7126020e0' target=_blank style='color:#2F92EE;'>#伤寒沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26020, encryptionId=ed7126020e0, topicName=伤寒沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c9cd34575980, createdName=zywlvao, createdTime=Thu Sep 19 15:07:00 CST 2019, time=2019-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012851, encodeId=5caf201285126, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Sep 24 12:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399149, encodeId=700b13991495d, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615496, encodeId=946816154960e, content=<a href='/topic/show?id=280196865f7' target=_blank style='color:#2F92EE;'>#镰状细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96865, encryptionId=280196865f7, topicName=镰状细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb4819654385, createdName=1508842480_96220443, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351546, encodeId=a49a351546cb, content=学习了，涨知识了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Nov 04 20:22:03 CST 2018, time=2018-11-04, status=1, ipAttribution=)]
    2019-09-24 cmj8wellington

    #Dis#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1899250, encodeId=5895189925088, content=<a href='/topic/show?id=6f746e94170' target=_blank style='color:#2F92EE;'>#特异性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67941, encryptionId=6f746e94170, topicName=特异性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Jun 25 13:07:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739834, encodeId=5a411e39834ec, content=<a href='/topic/show?id=ed7126020e0' target=_blank style='color:#2F92EE;'>#伤寒沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26020, encryptionId=ed7126020e0, topicName=伤寒沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c9cd34575980, createdName=zywlvao, createdTime=Thu Sep 19 15:07:00 CST 2019, time=2019-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012851, encodeId=5caf201285126, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Sep 24 12:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399149, encodeId=700b13991495d, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615496, encodeId=946816154960e, content=<a href='/topic/show?id=280196865f7' target=_blank style='color:#2F92EE;'>#镰状细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96865, encryptionId=280196865f7, topicName=镰状细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb4819654385, createdName=1508842480_96220443, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351546, encodeId=a49a351546cb, content=学习了，涨知识了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Nov 04 20:22:03 CST 2018, time=2018-11-04, status=1, ipAttribution=)]
    2018-11-06 lifestar

    #沙门氏菌#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1899250, encodeId=5895189925088, content=<a href='/topic/show?id=6f746e94170' target=_blank style='color:#2F92EE;'>#特异性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67941, encryptionId=6f746e94170, topicName=特异性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Jun 25 13:07:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739834, encodeId=5a411e39834ec, content=<a href='/topic/show?id=ed7126020e0' target=_blank style='color:#2F92EE;'>#伤寒沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26020, encryptionId=ed7126020e0, topicName=伤寒沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c9cd34575980, createdName=zywlvao, createdTime=Thu Sep 19 15:07:00 CST 2019, time=2019-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012851, encodeId=5caf201285126, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Sep 24 12:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399149, encodeId=700b13991495d, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615496, encodeId=946816154960e, content=<a href='/topic/show?id=280196865f7' target=_blank style='color:#2F92EE;'>#镰状细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96865, encryptionId=280196865f7, topicName=镰状细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb4819654385, createdName=1508842480_96220443, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351546, encodeId=a49a351546cb, content=学习了，涨知识了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Nov 04 20:22:03 CST 2018, time=2018-11-04, status=1, ipAttribution=)]
    2018-11-06 1508842480_96220443

    #镰状细胞#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1899250, encodeId=5895189925088, content=<a href='/topic/show?id=6f746e94170' target=_blank style='color:#2F92EE;'>#特异性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67941, encryptionId=6f746e94170, topicName=特异性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc7a157, createdName=jinweidong, createdTime=Tue Jun 25 13:07:00 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739834, encodeId=5a411e39834ec, content=<a href='/topic/show?id=ed7126020e0' target=_blank style='color:#2F92EE;'>#伤寒沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26020, encryptionId=ed7126020e0, topicName=伤寒沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c9cd34575980, createdName=zywlvao, createdTime=Thu Sep 19 15:07:00 CST 2019, time=2019-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012851, encodeId=5caf201285126, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Sep 24 12:07:00 CST 2019, time=2019-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399149, encodeId=700b13991495d, content=<a href='/topic/show?id=1e7464490b7' target=_blank style='color:#2F92EE;'>#沙门氏菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64490, encryptionId=1e7464490b7, topicName=沙门氏菌)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/dZj08ckjV0K1emuaDxP7G2DicoLPC5gxtjiatZukfCclP1r3RbxcTgibCpicZkfazrzGUU2iatBBWBNuPTP10a3g5Mw/0, createdBy=12552195639, createdName=lifestar, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615496, encodeId=946816154960e, content=<a href='/topic/show?id=280196865f7' target=_blank style='color:#2F92EE;'>#镰状细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96865, encryptionId=280196865f7, topicName=镰状细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb4819654385, createdName=1508842480_96220443, createdTime=Tue Nov 06 11:07:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=351546, encodeId=a49a351546cb, content=学习了，涨知识了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Sun Nov 04 20:22:03 CST 2018, time=2018-11-04, status=1, ipAttribution=)]
    2018-11-04 王秀

    学习了，涨知识了！

    0