Diabetes Care:1型糖尿病患者房颤的危险因素

2019-06-08 xing.T 网络

由此可见,1型糖尿病患者房颤的最主要危险因素是年龄较大、心血管合并症和肾脏并发症,而肥胖、高血压和高血糖则影响较小。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员旨在确定与1型糖尿病患者心房颤动风险增加相关的变量。

研究人员对2001年1月1日至2013年12月31日期间瑞典国家糖尿病登记处随访的1型糖尿病患者进行了一项队列研究。中位随访时间为9.7年(四分位数间为5.2-13.0),研究人员使用调整的Cox回归研究潜在危险因素与入院心房颤动之间的关联。为了比较每个危险因素的影响,估计每1个SD的风险梯度。 

在包含36258名1型糖尿病患者的队列中,749名患者在随访期间发生了房颤。年龄较大,男性,肾脏并发症,BMI和HbA1c升高,冠状动脉疾病,心力衰竭和心脏瓣膜病增加了房颤的风险。年龄,大量白蛋白尿肾功能不全的迹象和估计的肾小球滤过率降低与心房颤动的最高风险梯度相关。高血压,严重肥胖(BMI>35kg/m2)和HbA1c水平升高(>9.6%)与风险增加有关,但未发现高脂血症或吸烟之间的相关性。

由此可见,1型糖尿病患者房颤的最主要危险因素是年龄较大、心血管合并症和肾脏并发症,而肥胖、高血压和高血糖则影响较小。 

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    2019-06-11 184****9840

    学习了,谢谢分享。

    0

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    2019-06-08 misszhang

    谢谢MedSci提供最新的资讯

    0

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