Heart：经辅助生殖技术出生的婴儿发生严重先心病的风险大大增高！

2018-05-15 MedSci MedSci原创

本研究的目的旨在评估经各种不孕症治疗后出生的活产婴儿发生青紫型先天性心脏病（CCHDs）的风险。本研究纳入了美国2011年至2014年出生的14242267例活产婴儿，其中101494例是经辅助生殖技术（ART）出生的，81242例是经非ART不孕症治疗出生的，CCHDs在ART组、非ART组和自然受孕组出生婴儿的发病率分别是393/100892 (0.39%)、 210/80884 (0.26%

本研究的目的旨在评估经各种不孕症治疗后出生的活产婴儿发生青紫型先天性心脏病（CCHDs）的风险。

本研究纳入了美国2011年至2014年出生的14242267例活产婴儿，其中101494例是经辅助生殖技术（ART）出生的，81242例是经非ART不孕症治疗出生的，CCHDs在ART组、非ART组和自然受孕组出生婴儿的发病率分别是393/100892 (0.39%)、 210/80884 (0.26%) 和10749/14020749 (0.08%)。与自然受孕组相比，ART组婴儿发生CCHD的风险明显增高（RR：2.4， 95% CI 2.1 - 2.7），非ART不孕症治疗组婴儿发生CCHD的风险也明显增高（RR 1.9， 95% CI 1.6 - 2.2）。

研究结果显示，经各种不孕症治疗后出生的活产婴儿发生青紫型先天性心脏病的风险要明显高于自然受孕的婴儿。

原始出处：

Alireza A et al.Cyanotic congenital heart disease following fertility treatments in the United States from 2011 to 2014.Heart.2018 May.

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#插入话题

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2018-05-17 ssnine

#先心病#

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2018-05-17 zhaojie88

#ART#

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2018-05-17 ms691033630344116

#辅助生殖技术#

46 0
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2018-05-17 liuxiaona

#增高#

31 0
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2018-05-17 slcumt

#HEART#

42 0
[GetPortalCommentsPageByObjectIdResponse(id=1311475, encodeId=03d313114e515, content=<a href='/topic/show?id=a12628e0852' target=_blank style='color:#2F92EE;'>#先心病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28708, encryptionId=a12628e0852, topicName=先心病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356785, encodeId=99851356e8555, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1542645, encodeId=c26e154264545, content=<a href='/topic/show?id=400c9369608' target=_blank style='color:#2F92EE;'>#辅助生殖技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93696, encryptionId=400c9369608, topicName=辅助生殖技术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7f7313422862, createdName=ms691033630344116, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561601, encodeId=f8cd156160108, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562900, encodeId=7d6f156290059, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567610, encodeId=41a9156e6102c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315392, encodeId=84203153922e, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue May 15 18:59:59 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315336, encodeId=349131533604, content=风险大的很啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Tue May 15 12:02:31 CST 2018, time=2018-05-15, status=1, ipAttribution=)]
2018-05-17 liuxiaona

#增高#

33 0
[GetPortalCommentsPageByObjectIdResponse(id=1311475, encodeId=03d313114e515, content=<a href='/topic/show?id=a12628e0852' target=_blank style='color:#2F92EE;'>#先心病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28708, encryptionId=a12628e0852, topicName=先心病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356785, encodeId=99851356e8555, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1542645, encodeId=c26e154264545, content=<a href='/topic/show?id=400c9369608' target=_blank style='color:#2F92EE;'>#辅助生殖技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93696, encryptionId=400c9369608, topicName=辅助生殖技术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7f7313422862, createdName=ms691033630344116, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561601, encodeId=f8cd156160108, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562900, encodeId=7d6f156290059, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567610, encodeId=41a9156e6102c, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Thu May 17 01:15:00 CST 2018, time=2018-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315392, encodeId=84203153922e, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue May 15 18:59:59 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315336, encodeId=349131533604, content=风险大的很啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Tue May 15 12:02:31 CST 2018, time=2018-05-15, status=1, ipAttribution=)]
2018-05-15 虈亣靌

学习一下很不错

68 0
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2018-05-15 易水河

风险大的很啊

0 0

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