Stroke:全谷物摄入量与缺血性卒中风险分析!

2017-11-11 xing.T MedSci原创

由此可见,尽管全谷类食物的总体摄入量与较低的缺血性卒中的风险无关,但全谷类冷早餐谷类食品和全麸的摄入量与较低的缺血性卒中风险显著相关。需要在其他人群中进行更多的研究来重复个别谷物食品与缺血性卒中风险之间的关联。

较高的全谷物摄入量可能对心脏具有好处,虽然针对卒中风险的结果尚未明确。单种全谷物食品对缺血性卒中的潜在影响还没有被研究过。近日,卒中领域权威杂志Stroke上针对这一问题发表了一篇研究文章。

研究人员采用Cox比例风险模型分析了来自于护士健康研究的71750例女性和来自于健康专业随访研究的42823名男性与缺血性脑卒中的750名女性和42 823名男性全谷物摄入与缺血性卒中之间的相关性,在研究之初(分别为1984年和1986年)这些参与者没有心血管疾病、糖尿病、癌症,随访至2010年。研究人员采用验证过的半定量食物频率问卷评估了全谷类食物的摄入量,包括全谷类冷早餐麦片、黑面包、燕麦片、糙米、爆米花、麦麸和胚芽。通过病历回顾证实了参与者自我报告的缺血性卒中事件。

在2820128人次每年的随访期间,两个队列共有2458例缺血性卒中患者被确诊。在调整协变量后,全谷物摄入量与缺血性卒中无关:与极端摄入水平相比联合风险比(95%可信区间)为1.04(0.91-1.19)。然而,经多因素调整后,全谷物早餐麦片和全麸摄入与缺血性卒中成反比:联合风险比(95%可信区间)分别为0.88(0.80-0.96;趋势P=0.008)和0.89(0.79-1;趋势P=0.004)。其他全谷物食品与缺血性中风的风险无关。

由此可见,尽管全谷类食物的总体摄入量与较低的缺血性卒中的风险无关,但全谷类冷早餐谷类食品和全麸的摄入量与较低的缺血性卒中风险显著相关。需要在其他人群中进行更多的研究来重复个别谷物食品与缺血性卒中风险之间的关联。

原始出处:

Juan Juan,et al. Whole Grain Consumption and Risk of Ischemic Stroke Results From 2 Prospective Cohort Studies.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.018979

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    2018-05-30 licz0435
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    2017-11-11 Y—xianghai

    学习了新知识

    0

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    2017-11-11 lyh994

    不同地区人群有无差异?

    0

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