JCEM:体力活动一定可以改善糖尿病前期患者血糖状况?那可说不准

2017-08-04 MedSci MedSci原创

大家都知道体力活动(PA)对于糖尿病患者的益处,但是你知道PA对于由OGTT或HbA1c诊断的糖尿病前期患者的血糖改善有不同影响么?

大家都知道体力活动(PA)对于糖尿病患者的益处,但是你知道PA对于由OGTT或HbA1c诊断糖尿病前期患者的血糖改善有不同影响么?

近日在JCEM上发表的一篇文章则研究了PA与由血糖或HbA1c标准确诊的糖尿病前期患者血糖改善之间的关系。该研究纳入了957例由孤立空腹血糖受损(i-IFG)、孤立糖耐量异常(i-IGT)或两者(IFG+IGT)确诊的糖尿病前期患者及457例由HbA1c确诊的糖尿病前期患者。研究人员对5年随访内PA与葡萄糖相关改变的关联进行了分析,并利用递归分割分析了基线PA与恢复正常血糖概率之间的关联的异质性。

研究结果显示经过5年的随访,405例(42%)由葡萄糖确诊的糖尿病前期患者恢复至正常糖代谢(NGT)。5年中增加中至高强度PA与胰岛素敏感性和胰岛β细胞功能的改善有关,但是PA一般与恢复至NGT无关。只有在≥50岁有i-IFG或i-IGT的女性患者中较高强度的PA,以较高的概率发生NGT逆转。而在有HbA1c确诊的糖尿病前期患者中,只有20例(4.4%)逆转正常血糖,且PA与血糖指标改善并不相关。

从上述研究可以看出PA对有i-IFG或i-IGT老年女性逆转至血糖正常尤为重要。而由HbA1c确诊的糖尿病前期患者逆转至正常血糖的概率较低,且其血糖变化与PA无关。

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    2017-12-25 smallant2015
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    2017-08-25 achengzhao
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    2017-08-06 虈亣靌

    学习了,谢谢分享

    0

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    2017-08-05 186****0580(小山羊)

    学习了谢谢了。

    0

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    2017-08-05 明天会更好!

    谢谢分享,学习了

    0

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    2017-08-04 天涯183

    非常好的文章,学习了,很受益

    0

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