阜外医院舒畅等研究称,对于主动脉病变同时合并冠心病患者,杂交手术疗效满意

2019-08-14 不详 中国循环杂志

主动脉病变合并冠心病很常见,其治疗方式包括分期手术和同期手术。具体到每一例患者如何选择治疗策略还需考虑个体化因素。

主动脉病变合并冠心病很常见,其治疗方式包括分期手术和同期手术。具体到每一例患者如何选择治疗策略还需考虑个体化因素。

阜外医院舒畅等发表研究称,胸主动脉腔内修复术(TEVAR)联合冠状动脉(冠脉)旁路移植术(CABG)“一站式”治疗冠心病合并胸主动脉疾病中期疗效满意,若需同期行去分支手术为TEVAR 创造锚定区,会增加手术时间和手术风险。

研究者对于部分锚定区不足甚至主动脉病变累及弓部的患者,采取先行升主动脉至弓部动脉人工血管搭桥的办法,扩展覆膜支架近端锚定区,再行TEVAR 手术。

研究纳入在阜外医院血管外科中心接受“一站式”TEVAR 联合CABG 手术治疗冠心病合并胸主动脉疾病患者20 例,男性18 例。

20例中,1 例植入胸主动脉支架2 枚, 19 例植入胸主动脉支架1 枚,其中3 例分别同期实施腹主动脉覆膜支架植入术1 例、右侧髂总动脉支架植入术1 例和颈动脉内膜剥脱术1 例;平均冠脉搭桥[2.4±0.94(1~4)] 支,10例(50%)采用乳内动脉桥。

20 例患者平均住院时间[22.4±11.6(8~58)] 天,6 例(30%)患者接受输血治疗;低心排综合征1 例(5%),采用体外膜氧合器(ECMO)辅助治疗,后又因胸液多二次开胸止血;术后30 天死亡2 例(10%)。

17 例患者(失访1 例)均获得门诊或电话随访,平均随访时间[13.4±13.6(1~49)] 个月,2 例患者分别于术后12 个月、49 个月因脑血管意外死亡,15 例患者临床症状消失或明显减轻,生活质量改善,无手术相关死亡。

研究者称,总体而言,单纯TEVAR 联合CABG 手术手术风险相对较低,而当主动脉病变近端锚定区不足需同时行去分支手术,再行TEVAR 联合CABG 时,由于手术操作复杂程度和手术时长显着增加,手术风险仍然较高。

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    2019-08-15 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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