Diabetes Care:1型糖尿病患者冠状动脉造影的特征和预后!

2018-02-21 xing.T MedSci原创

由此可见,1型糖尿病患者接受冠状动脉造影时,女性和男性的冠心病严重程度几乎相同,总的长期死亡率没有差别。与一般人群相比,1型糖尿病女性患者的死亡率比男性患者高。这些数据支持1型糖尿病减轻了普通人群中男女心血管风险的差异。

近日,糖尿病领域权威杂志Diabetes Care上发表了研究文章,该研究旨在描述1型糖尿病患者冠状动脉病变(CAD)和预后的性别特征。

在2001年-2013年期间,所有纳入瑞典冠状动脉造影和血管成形术登记中心、瑞典国家糖尿病登记中心的接受冠状动脉造影的1型糖尿病患者,随访至2013年12月31日,评估死亡率。冠状动脉造影分为正常和一、二、三和左主干病变。

2776例(42%名女性)患者平均年龄为58岁(SD为11),随访7.2年(SD为2.2)。女性糖尿病病程较长(女性37±14 vs. 男性34±14岁,P<0.001),视网膜病变较多(68% vs. 65%,P=0.050),而尿微量白蛋白不常见(41% vs. 51%,P<0.001)。女性和男性冠状动脉造影的适应证没有显著差异。冠心病的严重程度女性稍轻(正常血管造影23.5% vs. 19.1%,三支血管和左主干病变34.5% vs. 40.4%,P=0.002),而死亡率没有差异(调整后的风险比为1.03 95%可信区间为0.88-1.20;P=0.754)。女性第一年的标准死亡率为7.49(5.73-9.62),男性为4.58(3.60-5.74)。

由此可见,1型糖尿病患者接受冠状动脉造影时,女性和男性的冠心病严重程度几乎相同,总的长期死亡率没有差别。与一般人群相比,1型糖尿病女性患者的死亡率比男性患者高。这些数据支持1型糖尿病减轻了普通人群中男女心血管风险的差异。

原始出处:

Viveca Ritsinger,Characteristics and Prognosis in Women and Men With Type 1 Diabetes Undergoing Coronary Angiography: A Nationwide Registry Report.Diabetes Care 2018. https://doi.org/10.2337/dc17-2352

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createdBy=908d9134595, createdName=sodoo, createdTime=Fri Feb 23 01:25:00 CST 2018, time=2018-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=290062, encodeId=e7b9290062e7, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Feb 23 00:44:42 CST 2018, time=2018-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289749, encodeId=76f5289e4943, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJpBl6xwMmnsKibwxcAIltOH3nnCEQbNE6TDbYtCKe8hYI0oJrbduNqnJraM1PyyjPKU1suAzicYPaA/132, createdBy=eeaf2031798, createdName=海之蓝, createdTime=Wed Feb 21 20:37:53 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289729, encodeId=7b94289e2928, content=学习..谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Feb 21 16:59:42 CST 2018, time=2018-02-21, status=1, ipAttribution=)]
    2018-02-23 sodoo
  8. [GetPortalCommentsPageByObjectIdResponse(id=1638426, encodeId=67b116384263f, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri May 04 03:25:00 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901986, encodeId=37881901986bb, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, 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createdName=海之蓝, createdTime=Wed Feb 21 20:37:53 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289729, encodeId=7b94289e2928, content=学习..谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Feb 21 16:59:42 CST 2018, time=2018-02-21, status=1, ipAttribution=)]
    2018-02-23 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

  9. 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createdName=海之蓝, createdTime=Wed Feb 21 20:37:53 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289729, encodeId=7b94289e2928, content=学习..谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Feb 21 16:59:42 CST 2018, time=2018-02-21, status=1, ipAttribution=)]
    2018-02-21 海之蓝

    学习

    0

  10. 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createdName=海之蓝, createdTime=Wed Feb 21 20:37:53 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=289729, encodeId=7b94289e2928, content=学习..谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Feb 21 16:59:42 CST 2018, time=2018-02-21, status=1, ipAttribution=)]
    2018-02-21 惠映实验室

    学习..谢谢分享.

    0

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