Biochem Biophys Res Commun:意料之外的抗癌物质,人乳

2017-05-19 佚名 煎蛋网

科学家们发现人乳含有一种能够杀死肿瘤细胞的物质之后,就开始利用它来对抗癌症。研究人员们在膀胱癌病人身上进行的试验已展现出有意义的结果,他们相信人乳中含有的化合物 (昵称哈姆雷特),也能够对抗大肠癌和子宫颈癌。他们还表示这种化合物能够驻扎在癌细胞里,并且对健康细胞无害。因此它不会给人带来让人虚弱的化疗副作用。做出这一开创性发现的 Catharina Svanborg 教授表示:“哈姆雷特的能力非常神

科学家们发现人乳含有一种能够杀死肿瘤细胞的物质之后,就开始利用它来对抗癌症。

研究人员们在膀胱癌病人身上进行的试验已展现出有意义的结果,他们相信人乳中含有的化合物 (昵称哈姆雷特),也能够对抗大肠癌和子宫颈癌。

他们还表示这种化合物能够驻扎在癌细胞里,并且对健康细胞无害。因此它不会给人带来让人虚弱的化疗副作用。

做出这一开创性发现的 Catharina Svanborg 教授表示:“哈姆雷特的能力非常神奇,它可以针对性地杀死癌细胞。”

她还说人乳含有一种名为乳清蛋白的蛋白质,当它进入人体肠道后,就会被转变成对抗癌症的机构。

Svanborg 教授是瑞典隆德大学的免疫学家,她曾在研究抗生素的时候意外发现了能够杀死癌细胞的物质。

她说道:“我们正在寻找新的抗菌剂,而新鲜的人乳是抗菌剂的不错来源。在某个实验中,我们需要用到人类细胞和细菌,最后出于实际理由我们选择了人类的肿瘤细胞。令我们吃惊的是,当我们加入了人乳中的这种化合物之后,肿瘤细胞就死掉了。这是一个极其偶然的发现。”

这种物质能够以多种方式攻击癌细胞。首先它会避开癌细胞的外层防御,之后以“发电站”线粒体和“使用指南”细胞核为目标。这些行为能够切断癌细胞的能量供应,诱导它们实施自杀行为,这就叫诱导癌细胞凋亡。

在膀胱癌病人身上的早期试验显示,注入了哈姆雷特的病人,会在几天内让死亡的癌细胞随着尿液排出身体。

目前研究人员们正准备将哈姆雷特与安慰剂进行对比试验。

原始出处:

Ho JC, Nadeem A, Svanborg C.HAMLET - A protein-lipid complex with broad tumoricidal activity.Biochem Biophys Res Commun. 2017 Jan 15

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    2017-05-27 sunylz
  2. [GetPortalCommentsPageByObjectIdResponse(id=1917493, encodeId=43d1191e4934d, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat May 27 17:32:00 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2087034, encodeId=a9aa208e034d3, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Thu Apr 26 05:32:00 CST 2018, time=2018-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1707525, encodeId=c2701e0752593, content=<a href='/topic/show?id=9f7c99e256' target=_blank style='color:#2F92EE;'>#IOP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9972, encryptionId=9f7c99e256, topicName=IOP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb031431834, createdName=124987c6m46暂无昵称, createdTime=Sat Jan 20 21:32:00 CST 2018, time=2018-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200492, encodeId=53c7200492b6, content=神奇了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Sat May 20 16:46:13 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200303, encodeId=578e20030304, content=这个研究有意思!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Sat May 20 08:14:45 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200203, encodeId=3b7a200203e1, content=好神奇,谢谢分享!但是牛奶会怎么样?, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/29/6902c9c65fe215fc96c6d153c8590e95.JPG, createdBy=f9312054548, createdName=138****1711, createdTime=Sat May 20 05:44:36 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200153, encodeId=7b3e200153ad, content=这也是发现新大陆了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Sat May 20 00:08:46 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2018-04-26 liuli5079
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    2017-05-20 luominglian113

    神奇了,谢谢分享

    0

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    2017-05-20 189****7206

    这个研究有意思!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1917493, encodeId=43d1191e4934d, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat May 27 17:32:00 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2087034, encodeId=a9aa208e034d3, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Thu Apr 26 05:32:00 CST 2018, time=2018-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1707525, encodeId=c2701e0752593, content=<a href='/topic/show?id=9f7c99e256' target=_blank style='color:#2F92EE;'>#IOP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9972, encryptionId=9f7c99e256, topicName=IOP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb031431834, createdName=124987c6m46暂无昵称, createdTime=Sat Jan 20 21:32:00 CST 2018, time=2018-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200492, encodeId=53c7200492b6, content=神奇了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Sat May 20 16:46:13 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200303, encodeId=578e20030304, content=这个研究有意思!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Sat May 20 08:14:45 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200203, encodeId=3b7a200203e1, content=好神奇,谢谢分享!但是牛奶会怎么样?, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/29/6902c9c65fe215fc96c6d153c8590e95.JPG, createdBy=f9312054548, createdName=138****1711, createdTime=Sat May 20 05:44:36 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200153, encodeId=7b3e200153ad, content=这也是发现新大陆了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Sat May 20 00:08:46 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-20 138****1711

    好神奇,谢谢分享!但是牛奶会怎么样?

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1917493, encodeId=43d1191e4934d, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat May 27 17:32:00 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2087034, encodeId=a9aa208e034d3, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Thu Apr 26 05:32:00 CST 2018, time=2018-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1707525, encodeId=c2701e0752593, content=<a href='/topic/show?id=9f7c99e256' target=_blank style='color:#2F92EE;'>#IOP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9972, encryptionId=9f7c99e256, topicName=IOP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6bb031431834, createdName=124987c6m46暂无昵称, createdTime=Sat Jan 20 21:32:00 CST 2018, time=2018-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200492, encodeId=53c7200492b6, content=神奇了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Sat May 20 16:46:13 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200303, encodeId=578e20030304, content=这个研究有意思!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Sat May 20 08:14:45 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200203, encodeId=3b7a200203e1, content=好神奇,谢谢分享!但是牛奶会怎么样?, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/29/6902c9c65fe215fc96c6d153c8590e95.JPG, createdBy=f9312054548, createdName=138****1711, createdTime=Sat May 20 05:44:36 CST 2017, time=2017-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=200153, encodeId=7b3e200153ad, content=这也是发现新大陆了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Sat May 20 00:08:46 CST 2017, time=2017-05-20, status=1, ipAttribution=)]
    2017-05-20 Drhzm308

    这也是发现新大陆了

    0

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