J Oral Rehabil:经鼻咽气道支架治疗 OSA可被改善

2018-10-22 米思颖 编译 中国医学论坛报今日口腔

日本的一项研究显示,鼻咽气道支架(Nastent)装置可以改善阻塞性睡眠呼吸暂停(OSA),这预示着与下咽部相比,较窄的腭咽部对治疗反映出良好的敏感性和特异性。该论文10月3日在线发表于《口腔康复学杂志》(J Oral Rehabil)。


日本的一项研究显示,鼻咽气道支架(Nastent)装置可以改善阻塞性睡眠呼吸暂停(OSA),这预示着与下咽部相比,较窄的腭咽部对治疗反映出良好的敏感性和特异性。该论文10月3日在线发表于《口腔康复学杂志》(J Oral Rehabil)。

在一般人群中阻塞性睡眠呼吸暂停普遍的特点是在睡眠期间反复出现部分或完全上呼吸道塌陷。鼻咽气道支架是一种特别设计的预成型硅胶管,意图在睡眠时维持上呼吸道的通畅,减少打鼾和睡眠呼吸暂停。本研究的目的是确定鼻咽气道支架治疗的疗效,并对阻塞性睡眠呼吸暂停患者治疗效果进行预测。共有30名受试者参与此次研究,研究者利用获得的X线头颅定位侧位片对患者咽部和颅面形态进行分析,并在Nastent治疗前后利用便携式睡眠研究的方式对OSA进行评估。

结果为,共有29例受试者完成了这项研究,经过鼻咽气道支架治疗后的患者,呼吸事件指数(REI)显著下降(从22.4±14.1下降至15.7±10.4,P<0.01),动脉血氧饱和度显著增加 (从81.9±7.5上升至86.6±4.8,P<0.01)。受试者分为响应者和非响应者,其依据是与基线相比REI减少的幅度是否大于50%,该研究将受试者头侧片中下呼吸道宽度和中呼吸道宽度(IAW/MAW)之比作为呼吸道最窄位点指数,评估得出,相对于非响应者,响应者的下呼吸道宽度和中呼吸道宽度之比明显更高(响应者为1.4±0.9,非响应者为0.9±0.4,P<0.01),且当IAW/MAW为1.10时,对于响应者的预测疗效具有较高的准确性(灵敏度:90.9%,特异性:88.9%)。

原始出处:

Okuno K,et al.The efficacy of nasal airway stent (Nastent) on obstructive sleep apnea and prediction of treatment outcomes.J Oral Rehabil. 2018 Oct 3. doi: 10.1111/joor.12725. [Epub ahead of print]

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    2019-02-19 小几洁
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    2018-11-09 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

  4. 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time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350237, encodeId=3d3135023ed5, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:16 CST 2018, time=2018-10-23, status=1, ipAttribution=)]
    2018-10-29 一天没事干

    很好的学习机会

    0

  5. 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time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350237, encodeId=3d3135023ed5, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:16 CST 2018, time=2018-10-23, status=1, ipAttribution=)]
    2018-10-24 bioon3
  6. 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time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350237, encodeId=3d3135023ed5, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:16 CST 2018, time=2018-10-23, status=1, ipAttribution=)]
    2018-10-24 qjddjq
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time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350237, encodeId=3d3135023ed5, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:16 CST 2018, time=2018-10-23, status=1, ipAttribution=)]
    2018-10-23 Y—xianghai

    学习了长知识

    0

  8. 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href='/topic/show?id=f83866137f' target=_blank style='color:#2F92EE;'>#EHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6613, encryptionId=f83866137f, topicName=EHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937d11405368, createdName=qjddjq, createdTime=Wed Oct 24 13:36:00 CST 2018, time=2018-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350240, encodeId=19a03502402b, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:31 CST 2018, time=2018-10-23, status=1, ipAttribution=), 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time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350237, encodeId=3d3135023ed5, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:16 CST 2018, time=2018-10-23, status=1, ipAttribution=)]
    2018-10-23 Y—xianghai

    学习了长知识

    0

  9. 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time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350237, encodeId=3d3135023ed5, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:16 CST 2018, time=2018-10-23, status=1, ipAttribution=)]
    2018-10-23 Y—xianghai

    学习了长知识

    0

  10. 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time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350237, encodeId=3d3135023ed5, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 23 07:40:16 CST 2018, time=2018-10-23, status=1, ipAttribution=)]
    2018-10-23 Y—xianghai

    学习了长知识

    0