Sci Trans Med:无需电离辐射!科学家研发出无创心脏功能磁共振

2019-06-19 苏煜静 生物探索

在医院能够与挂号处PK人数的只有两个地方,一个是血液检查,另一个就是磁共振检查。随着检查技术的迅速发展,磁共振成像为医生提供了精准的医疗检测。

在医院能够与挂号处PK人数的只有两个地方,一个是血液检查,另一个就是磁共振检查。随着检查技术的迅速发展,磁共振成像为医生提供了精准的医疗检测。

近日,Lawson 健康研究所和Cedars-Sinai 医学中心的科学研究人员开发出一种安全可靠的无创心脏功能磁共振(cfMRI)技术,无需电离辐射、造影剂和针头便可以监测心肌氧合状况,在自由呼吸条件下进行无创,快速,全心脏成像,识别缺血性心脏病(IHD)。该研究成果发表在《Science Translational Medicine》上。

心肌氧合指的是血管向心肌供应心肌的能力,它是心脏功能的关键决定因素。心肌氧合损伤也是缺血性心脏病的一个决定性特征。检测心肌氧合可以帮助预防和指导干预急性IHD造成的危重病情。



cfMRI通过检验心脏对氧的敏感度来监测心肌氧合,最初的测试结果有较多的噪音和模糊的图像。研究人员认为,噪音实际上是心脏处理氧气过程中产生的变化。研究小组发现检测噪音实际上是研究心脏如何工作的一种新方法。


Cedars-Sinai的主要专家 图片来源:Cedars-Sinai医学中心

Cedars-Sinai医学中心生物医学成像研究所副所长Rohan Dharmakumar博士说:“我们打开了通往新时代的大门,开启了心脏压力测试以识别缺血性心脏病的全新方式。这种方法克服了目前所有诊断的局限性, 不再需要进行注射或像在跑步机上跑步那样的物理运动来进行测试。”

此外,使用cfMRI比现有的检查方法更安全,而且在疾病过程中提供更详细的信息和更早的信息。在通过临床试验初步测试后,这种临床试验可在几年内应用于患者。

除了研究冠状动脉性心脏病(冠心病)之外,该方法还可用于检测心脏血流受影响的其他情况,例如心梗或癌症治疗期间对心脏的损害。由于风险最小,这种新工具可以安全地在同一患者身上重复使用多次,以便更好地选择正确的治疗方案。

Lawson助理总监Frank Prato博士指出:“有了这个研究心脏如何工作的新途径,我们可以更多地探索氧气在健康和疾病中的作用。”

原始出处:Hsin-Jung Yang, Ilkay Oksuz, Damini Dey, et al. Accurate needle-free assessment of myocardial oxygenation for ischemic heart disease in canines using magnetic resonance imaging. Sci Trans Med.  29 May 2019

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    2019-10-14 bsmagic9140
  3. 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    2019-06-23 杏林小道

    进一台来哈哈

    0

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encryptionId=ed5ee332423, topicName=研发)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aea0290, createdName=lqvr, createdTime=Thu Jun 20 23:30:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341666, encodeId=f0691341666f4, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Thu Jun 20 23:30:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349378, encodeId=acf913493e8c1, content=<a href='/topic/show?id=838593e35b2' target=_blank style='color:#2F92EE;'>#辐射#</a>, beContent=null, objectType=article, 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href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Thu Jun 20 23:30:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609829, encodeId=3b1316098299f, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Jun 20 23:30:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
    2019-06-20 lqvr
  5. [GetPortalCommentsPageByObjectIdResponse(id=1662475, encodeId=c3ef16624e5d0, content=<a href='/topic/show?id=ae61e014686' target=_blank style='color:#2F92EE;'>#电离辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70146, encryptionId=ae61e014686, topicName=电离辐射)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a4e25405553, createdName=ms2536978994064944, createdTime=Tue May 19 08:30:00 CST 2020, time=2020-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1657183, encodeId=7504165e183b4, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, 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2019, time=2019-06-20, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1662475, encodeId=c3ef16624e5d0, content=<a href='/topic/show?id=ae61e014686' target=_blank style='color:#2F92EE;'>#电离辐射#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70146, encryptionId=ae61e014686, topicName=电离辐射)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a4e25405553, createdName=ms2536978994064944, createdTime=Tue May 19 08:30:00 CST 2020, time=2020-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1657183, encodeId=7504165e183b4, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, 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href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Thu Jun 20 23:30:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609829, encodeId=3b1316098299f, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Jun 20 23:30:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
    2019-06-20 jiyangfei
  7. 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2019, time=2019-06-20, status=1, ipAttribution=)]
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