Surv Ophthalmol.:体内角膜内皮再生研究的系统性回顾!

2017-08-12 cuiguizhong MedSci原创

比利时威利克安特卫普大学医学与健康科学学院眼科的Van den Bogerd B教授近日在Surv Ophthalmo杂志上发表了一篇综述,标题为"A Review of the Evidence for in vivo Corneal Endothelial Regeneration.",系统性的阐述了体内角膜内皮再生研究,并对术后并发症的病例报告进行了回顾讨论。

比利时威利克安特卫普大学医学与健康科学学院眼科的Van den Bogerd B教授近日在Surv Ophthalmo杂志上发表了一篇综述,标题为"A Review of the Evidence for in vivo Corneal Endothelial Regeneration.",系统性的阐述了体内角膜内皮再生研究,并对术后并发症的病例报告进行了回顾讨论。人的角膜内皮一直以来被认为是没有内源性修复潜能的非分裂的细胞层。病理学分析表明,角膜内皮功能丧失将引起角膜代偿失调,如果没有进行及时的治疗,将会导致失明。其中,主要的治疗方法是部分或全部进行角膜置换手术,这占全球角膜移植的40%。在他们发表的文章中,Van den Bogerd B系统的总结了术后并发症的病例报告,包括部分或者全部移植物脱离和导致术后基质裸露的各种情况。他们还论述了包括白内障和青光眼手术中的并发症,因为这些并发症也会引起角膜后部脱落。他们对有可能成为目前DMEK和DSAEK手术替代方案的新的治疗策略也进行了论述,包括部分移植和剥离坏死细胞层等方案。在他们讨论的一半以上的病例中,角膜不完全透明,或者没有角膜内皮

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    2017-08-14 snowpeakxu
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authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Sun Aug 13 07:37:06 CST 2017, time=2017-08-13, status=1, ipAttribution=)]
    2017-08-14 微笑人参

    谢谢!学习了

    0

  5. 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    2017-08-13 1e1b8538m79(暂无匿称)

    不错的文章,值得一读

    0

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    2017-08-13 Julie W

    其中一个假设是,存在健康的外周细胞可以成功的实现角膜再补偿,而这不需要额外提供供体细胞。这项发现对于角膜移植打开了新的机遇。

    0

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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Sun Aug 13 09:09:44 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233082, encodeId=13dc23308267, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8df42027719, createdName=小小瑞, createdTime=Sun Aug 13 07:47:19 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233075, encodeId=c3fd2330e5f3, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, 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    2017-08-13 龙胆草

    学习谢谢分享

    0

  8. 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    2017-08-13 执着追梦

    学习,谢谢分享

    0

  9. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Sun Aug 13 09:09:44 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233082, encodeId=13dc23308267, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8df42027719, createdName=小小瑞, createdTime=Sun Aug 13 07:47:19 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=233075, encodeId=c3fd2330e5f3, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Sun Aug 13 07:37:06 CST 2017, time=2017-08-13, status=1, ipAttribution=)]
    2017-08-13 小小瑞

    学习

    0

  10. 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    2017-08-13 Y—xianghai

    学习了新知识

    0