Lancet Infect Dis:HSV-2感染对HIV感染影响

2019-11-19 MedSci MedSci原创

研究认为,HIV 的巨大负担很可能归因于HSV-2感染。新的预防HSV-2感染干预措施不仅可以减少疱疹性生殖器溃疡疾病的流行,提高数百万人的生活质量,而且还可能对艾滋病毒的传播产生间接影响

2017年对55项前瞻性研究进行的系统回顾和荟萃分析发现,在单纯疱疹病毒2型(HSV-2)感染者中,经调整的HIV感染风险至少增加了三倍。近日研究人员评估了HSV-2感染对HIV发病率的潜在影响。

研究人员使用经典的流行病学公式,考察人口归因分数(PAF)、年龄(15-24岁、25-49岁和15-49岁)、性别和HSV-2感染时间。通过系统回顾和Meta分析,将HSV-2和HIV感染数据与汇总的相对风险(RR)估计相结合,计算出HSV-2感染对HIV感染的影响。

据估计,2016年有140万人因性行为而感染HIV病毒,而年龄在15-49岁之间的人中,有42万人(PAF 29.6%)是由HSV-2感染引起的。非洲地区(PAF:37.1%)、妇女(34.8%)、25-49岁个体(32.4%)和已感染HSV-2 (26.8%)人群中,HSV-2对HIV的影响最大。

研究认为,HIV 的巨大负担很可能归因于HSV-2感染。新的预防HSV-2感染干预措施不仅可以减少疱疹性生殖器溃疡疾病的流行,提高数百万人的生活质量,而且还可能对艾滋病毒的传播产生间接影响。

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    2022-12-27 ms6000001411380643 来自广东省

    希望国家重视!单纯疱疹要害死人,加快根治药物研究

    0

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    2020-03-18 howi
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  5. [GetPortalCommentsPageByObjectIdResponse(id=2107657, encodeId=436a210e65742, content=希望国家重视!单纯疱疹要害死人,加快根治药物研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=68a38490885, createdName=ms6000001411380643, createdTime=Tue Dec 27 12:43:13 CST 2022, time=2022-12-27, status=1, ipAttribution=广东省), GetPortalCommentsPageByObjectIdResponse(id=1830341, encodeId=b60818303413f, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Mar 18 02:58:00 CST 2020, time=2020-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720704, encodeId=16211e2070441, content=<a href='/topic/show?id=e9d791e02a' target=_blank style='color:#2F92EE;'>#HSV-2#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9170, encryptionId=e9d791e02a, topicName=HSV-2)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=28dd32934037, createdName=bnjfx@137.com, createdTime=Thu Jun 25 12:58:00 CST 2020, time=2020-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013099, encodeId=e590201309939, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Dec 17 00:58:00 CST 2019, time=2019-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1941648, encodeId=22b11941648bb, content=<a href='/topic/show?id=48c291689e' target=_blank style='color:#2F92EE;'>#HSV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9168, encryptionId=48c291689e, topicName=HSV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Sun Jun 07 09:58:00 CST 2020, time=2020-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375843, encodeId=1b2d3e5843ab, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/05/22/c26524b0b4ca80000d38f0294262c002.jpg, createdBy=3cf52015303, createdName=苏小雨, createdTime=Tue Nov 26 07:14:22 CST 2019, time=2019-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375556, encodeId=bbb03e5556b2, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Nov 20 05:08:37 CST 2019, time=2019-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375542, encodeId=0ef53e554222, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Tue Nov 19 19:08:35 CST 2019, time=2019-11-19, status=1, ipAttribution=)]
    2020-06-07 gracezdd
  6. [GetPortalCommentsPageByObjectIdResponse(id=2107657, encodeId=436a210e65742, content=希望国家重视!单纯疱疹要害死人,加快根治药物研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=68a38490885, createdName=ms6000001411380643, createdTime=Tue Dec 27 12:43:13 CST 2022, time=2022-12-27, status=1, ipAttribution=广东省), GetPortalCommentsPageByObjectIdResponse(id=1830341, encodeId=b60818303413f, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Mar 18 02:58:00 CST 2020, time=2020-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720704, encodeId=16211e2070441, content=<a href='/topic/show?id=e9d791e02a' target=_blank style='color:#2F92EE;'>#HSV-2#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9170, encryptionId=e9d791e02a, topicName=HSV-2)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=28dd32934037, createdName=bnjfx@137.com, createdTime=Thu Jun 25 12:58:00 CST 2020, time=2020-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013099, encodeId=e590201309939, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue Dec 17 00:58:00 CST 2019, time=2019-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1941648, encodeId=22b11941648bb, content=<a href='/topic/show?id=48c291689e' target=_blank style='color:#2F92EE;'>#HSV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9168, encryptionId=48c291689e, topicName=HSV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Sun Jun 07 09:58:00 CST 2020, time=2020-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375843, encodeId=1b2d3e5843ab, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/05/22/c26524b0b4ca80000d38f0294262c002.jpg, createdBy=3cf52015303, createdName=苏小雨, createdTime=Tue Nov 26 07:14:22 CST 2019, time=2019-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375556, encodeId=bbb03e5556b2, content=好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Nov 20 05:08:37 CST 2019, time=2019-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375542, encodeId=0ef53e554222, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Tue Nov 19 19:08:35 CST 2019, time=2019-11-19, status=1, ipAttribution=)]
    2019-11-26 苏小雨

    学习了,谢谢分享

    0

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    2019-11-20 yjs木玉

    好好好好好好

    0

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    2019-11-19 一个字-牛

    学习了谢谢分享

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