Int Arch Otorhinolaryngol:突发性感官听力损失与自身免疫系统疾病

2017-07-13 AlexYang MedSci原创

之前,有一些作者表述了突发性感官听力损失(SNHL)与系统性自身免疫疾病(SAD)的关系。免疫调节的SNHL很少的表现为单边突发SNHL,并且数年后在对侧耳中才表现出免疫调节的SNHL。鉴于早期和适当的治疗应用,免疫调节的SNHL作为少数可以逆转的SNHL之一,表现出了临床相关性。最近,有研究人员描述了患有先天突发性SNHL和SAD且与免疫调节SNHL可能性诊断相关病人的临床表现和听力学发现。更多

之前,有一些作者表述了突发性感官听力损失(SNHL)与系统性自身免疫疾病(SAD)的关系。免疫调节的SNHL很少的表现为单边突发SNHL,并且数年后在对侧耳中才表现出免疫调节的SNHL。鉴于早期和适当的治疗应用,免疫调节的SNHL作为少数可以逆转的SNHL之一,表现出了临床相关性。

最近,有研究人员描述了患有先天突发性SNHL和SAD且与免疫调节SNHL可能性诊断相关病人的临床表现和听力学发现。更多的是,研究人员试图评估患有突发性SNHL病人中SAD的流行情况。研究人员评估了339名患有突发性SNHL的病人。研究发现,13名(3.83%)病人遭受SAD。3名病人具有双边耳聋。研究人员同样在该样本中评估和描述了各种临床、流行病学和听力学因素。并且,在具有突发性SNHL病人中发现SAD的流行度与其是相关的。大多数病人具有耳鸣和头晕,并伴随着听力损失和单边耳聋;并且在调试时经历深远的听力损失。尽管开始治疗,大多数案例在听力阈值方面没有改善。明显的是,与具有未知病因的突发性SNHL相比,患有突发性SNHL和SAD的病人具有更严重的初始损伤、更高的双边耳聋比例、对治疗更低的响应和更差的预后。

原始出处:

Rossini BAA, Penido NO, Munhoz MSL et al. Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases. Int Arch Otorhinolaryngol. July 2017.

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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Thu Aug 24 22:01:09 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1951447, encodeId=22e3195144ed7, content=<a href='/topic/show?id=afc3532e51e' target=_blank style='color:#2F92EE;'>#感官听力损失#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53275, encryptionId=afc3532e51e, topicName=感官听力损失)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f98e185, createdName=psybestwish, createdTime=Tue Jan 02 02:40:00 CST 2018, time=2018-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235014, 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objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Mon Aug 07 10:24:57 CST 2017, time=2017-08-07, status=1, ipAttribution=)]
    2017-08-24 184****9840

    学习了谢谢分享

    0

  5. 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objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Mon Aug 07 10:24:57 CST 2017, time=2017-08-07, status=1, ipAttribution=)]
    2017-08-19 189****7206

    学习了谢谢分享

    0

  7. 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    2017-08-16 189****7206

    学习了受益匪浅

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    2017-08-11 130****4638

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    2017-08-09 130****4638

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    2017-08-07 184****9840

    学习了受益匪浅

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