Medicine (Baltimore):新生血管性青光眼治疗策略的分析

2019-04-18 Daniel Xu Daniel Xu

新生血管性青光眼(NVG)是一种较常见的难治性青光眼,临床中大约70%的病例继发于中央静脉阻塞、糖尿病视网膜病变等眼底疾病,并且最终导致患眼疼痛及视力丧失。

新生血管性青光眼(NVG一种较常见的难治性青光眼,临床大约70%的病例继发于中央静脉阻塞、糖尿病视网膜病变等眼底疾病,并且最终导致患眼疼痛及视力丧失。NVG的形成直接由前房角新生血管组织的增殖所引起,后者与血管内皮生长因子(VEGF)的表达增多密切相关。

研究人员在对已报告的1884NVG患者的临床疗效进行了分析。在众多青光眼治疗方法中,睫状体光凝、小梁切除术、虹膜周切术、青光眼阀、抗VEGF药物、丝裂霉素有助于提高手术的成功率,而视网膜光凝和玻璃体切割术则会降低患眼的手术成功率。他们的研究首次VEGF药物在NVG治疗的作用进行了Meta分析,为未来NVG治疗策略的制定提供重要参考

最后,研究人员指出,青光眼阀植入和注射VEGF药物这两种治疗方式能提高治愈率。

原始出处:

Dong Z, Gong J, Liao R, et al. Effectiveness of multiple therapeutic strategies in neovascular glaucoma patients: A PRISMA-compliant network meta-analysis. Medicine (Baltimore), 2018;97(14):e9897.

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    2019-08-10 shizhenshan
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    2019-11-09 jeanqiuqiu
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    2019-10-21 kalseyzl
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