Eur Raidol:穿个刺竟然搞出了气胸?经皮穿刺肺活检后气胸的发生率、危险因子和临床意义的时变分析。

2017-10-31 shaosai MedSci原创

经皮肺穿刺活检是肺癌诊断的一种方法。早在数十年前就有人利用这种方法来诊断肺癌,但是由于受到当时各种条件的限制,像放射学、病理学、穿刺器械等,这种检查方法并没有在临床上得到较大的开展。本研究旨在评价经皮穿刺肺活检(PLB)后相关气胸时间依赖性发病率、危险因子和临床意义,并将结果发表在Eur Raidol上。

经皮肺穿刺活检是肺癌诊断的一种方法。早在数十年前就有人利用这种方法来诊断肺癌,但是由于受到当时各种条件的限制,像放射学、病理学、穿刺器械等,这种检查方法并没有在临床上得到较大的开展。本研究旨在评价经皮穿刺肺活检(PLB)后相关气胸时间依赖性发病率、危险因子和临床意义,并将结果发表在Eur Raidol上。

本研究共纳入了自2012年1月-2015年11月的3251例共行3354次肺部病变螺旋锥束CT引导PLBs。利用COX、Logistic和线性回归分别分析来验证PLB后相关气胸时间依赖性危险因子、引流管植入和延长置管的危险因子。

共有915/3,354 PLBs (27.3 %)次发生气胸,其中230/915 (25.1 %)气胸发生自随访中。早期发生PLB相关气胸的危险因子包括肺气肿(HR=1.624)、病变较小(HR=0.922)、位置较深(HR=1.175)和穿刺时间过长(HR=1.036),而咯血是早期气胸发生的保护因子。775例(8.2 %)进行了胸腔置管引流。置管平均时间为3.2±2.0天。肺气肿(OR=2.400)和穿刺时间过长(OR=1.053)是置管的显着危险因子,年纪过大(参数估计=1.014)是延长置管的预测因子。

本研究表明PLB相关气胸的发生率为27.3%,其中25.1%发生在随访中,病变较小、肺气肿和病变位置较深是PLB相关气胸的显着危险因子。肺气肿和年纪过大分别与引流管置入和延迟引流管位置具有相关性。

原始出处:


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    2020-11-25 14701227m79暂无昵称

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    2018-04-23 wjywjy
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topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311896, encodeId=3c7f1311896c5, content=<a href='/topic/show?id=21a6e54280e' target=_blank style='color:#2F92EE;'>#穿刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75428, encryptionId=21a6e54280e, topicName=穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b48400, createdName=rgjl, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441837, encodeId=1486144183ea8, content=<a href='/topic/show?id=ee95638550d' target=_blank style='color:#2F92EE;'>#气胸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63855, encryptionId=ee95638550d, topicName=气胸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b0f4898732, createdName=12498c32m69暂无昵称, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
  5. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033852, encodeId=42952033852fb, content=<a href='/topic/show?id=852b216824' target=_blank style='color:#2F92EE;'>#AID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2168, encryptionId=852b216824, topicName=AID)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Mon Apr 23 10:36:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922267, encodeId=bf22192226e94, content=<a href='/topic/show?id=86fd36e769e' target=_blank style='color:#2F92EE;'>#危险因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36776, encryptionId=86fd36e769e, topicName=危险因子)], attachment=null, authenticateStatus=null, createdAvatar=, 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encryptionId=edd6e842119, topicName=经皮穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Wed Apr 04 01:36:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258176, encodeId=04082581e667, content=不错啊文章值得一读., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Nov 02 23:00:41 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278047, encodeId=467c12e804762, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311896, encodeId=3c7f1311896c5, content=<a href='/topic/show?id=21a6e54280e' target=_blank style='color:#2F92EE;'>#穿刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75428, encryptionId=21a6e54280e, topicName=穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b48400, createdName=rgjl, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441837, encodeId=1486144183ea8, content=<a href='/topic/show?id=ee95638550d' target=_blank style='color:#2F92EE;'>#气胸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63855, encryptionId=ee95638550d, topicName=气胸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b0f4898732, createdName=12498c32m69暂无昵称, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=902214, encodeId=4f1c90221470, content=我爱学习,学习使我快乐我爱学习,学习使我快乐我爱学习,学习使我快乐我爱学习,学习使我快乐,。,。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7b245183802, createdName=14701227m79暂无昵称, createdTime=Wed Nov 25 16:32:47 CST 2020, time=2020-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1703502, encodeId=4ac71e03502f6, content=<a href='/topic/show?id=327e9425fc' target=_blank style='color:#2F92EE;'>#IDO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9425, encryptionId=327e9425fc, topicName=IDO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e3a30514791, createdName=tongyongming, createdTime=Mon Nov 27 07:36:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033852, encodeId=42952033852fb, content=<a href='/topic/show?id=852b216824' target=_blank style='color:#2F92EE;'>#AID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2168, encryptionId=852b216824, topicName=AID)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Mon Apr 23 10:36:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922267, encodeId=bf22192226e94, content=<a href='/topic/show?id=86fd36e769e' target=_blank style='color:#2F92EE;'>#危险因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36776, encryptionId=86fd36e769e, topicName=危险因子)], attachment=null, authenticateStatus=null, createdAvatar=, 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encryptionId=edd6e842119, topicName=经皮穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Wed Apr 04 01:36:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258176, encodeId=04082581e667, content=不错啊文章值得一读., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Nov 02 23:00:41 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278047, encodeId=467c12e804762, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311896, encodeId=3c7f1311896c5, content=<a href='/topic/show?id=21a6e54280e' target=_blank style='color:#2F92EE;'>#穿刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75428, encryptionId=21a6e54280e, topicName=穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b48400, createdName=rgjl, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441837, encodeId=1486144183ea8, content=<a href='/topic/show?id=ee95638550d' target=_blank style='color:#2F92EE;'>#气胸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63855, encryptionId=ee95638550d, topicName=气胸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b0f4898732, createdName=12498c32m69暂无昵称, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
  7. 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encryptionId=edd6e842119, topicName=经皮穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Wed Apr 04 01:36:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258176, encodeId=04082581e667, content=不错啊文章值得一读., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Nov 02 23:00:41 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278047, encodeId=467c12e804762, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311896, encodeId=3c7f1311896c5, content=<a href='/topic/show?id=21a6e54280e' target=_blank style='color:#2F92EE;'>#穿刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75428, encryptionId=21a6e54280e, topicName=穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b48400, createdName=rgjl, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441837, encodeId=1486144183ea8, content=<a href='/topic/show?id=ee95638550d' target=_blank style='color:#2F92EE;'>#气胸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63855, encryptionId=ee95638550d, topicName=气胸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b0f4898732, createdName=12498c32m69暂无昵称, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
    2017-11-02 1e1b8538m79(暂无匿称)

    不错啊文章值得一读.

    0

  8. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033852, encodeId=42952033852fb, content=<a href='/topic/show?id=852b216824' target=_blank style='color:#2F92EE;'>#AID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2168, encryptionId=852b216824, topicName=AID)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Mon Apr 23 10:36:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922267, encodeId=bf22192226e94, content=<a href='/topic/show?id=86fd36e769e' target=_blank style='color:#2F92EE;'>#危险因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36776, encryptionId=86fd36e769e, topicName=危险因子)], attachment=null, authenticateStatus=null, createdAvatar=, 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encryptionId=edd6e842119, topicName=经皮穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Wed Apr 04 01:36:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258176, encodeId=04082581e667, content=不错啊文章值得一读., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Nov 02 23:00:41 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278047, encodeId=467c12e804762, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311896, encodeId=3c7f1311896c5, content=<a href='/topic/show?id=21a6e54280e' target=_blank style='color:#2F92EE;'>#穿刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75428, encryptionId=21a6e54280e, topicName=穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b48400, createdName=rgjl, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441837, encodeId=1486144183ea8, content=<a href='/topic/show?id=ee95638550d' target=_blank style='color:#2F92EE;'>#气胸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, 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    2017-11-02 smlt2008
  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2033852, encodeId=42952033852fb, content=<a href='/topic/show?id=852b216824' target=_blank style='color:#2F92EE;'>#AID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2168, encryptionId=852b216824, topicName=AID)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Mon Apr 23 10:36:00 CST 2018, time=2018-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1922267, encodeId=bf22192226e94, content=<a href='/topic/show?id=86fd36e769e' target=_blank style='color:#2F92EE;'>#危险因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36776, encryptionId=86fd36e769e, topicName=危险因子)], attachment=null, authenticateStatus=null, createdAvatar=, 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encryptionId=edd6e842119, topicName=经皮穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Wed Apr 04 01:36:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258176, encodeId=04082581e667, content=不错啊文章值得一读., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Nov 02 23:00:41 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278047, encodeId=467c12e804762, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311896, encodeId=3c7f1311896c5, content=<a href='/topic/show?id=21a6e54280e' target=_blank style='color:#2F92EE;'>#穿刺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75428, encryptionId=21a6e54280e, topicName=穿刺)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b48400, createdName=rgjl, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441837, encodeId=1486144183ea8, content=<a href='/topic/show?id=ee95638550d' target=_blank style='color:#2F92EE;'>#气胸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63855, encryptionId=ee95638550d, topicName=气胸)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b0f4898732, createdName=12498c32m69暂无昵称, createdTime=Thu Nov 02 13:36:00 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
    2017-11-02 rgjl
  10. 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