Int J Dev Neurosci:感觉神经性听力损失患者的左枕外侧皮质厚度减少

2019-06-16 AlexYang MedSci原创

感觉神经性听力损失患者(SNHL)倾向于表现出语言发育延迟、执行功能缺陷和视觉认知障碍,甚至是听力扩大和耳蜗移植介入之后,仍旧表现出上述情况,表明了SNHL患者中大脑结构和功能已经发生了改变。最近,有研究人员调查了30名SNHL儿童中大脑MRI结构情况(18名轻度到中度SNHL(M-M),12名重度到永久性SNHL(M-P)),并与性别和年龄相匹配的正常对照(NC)进行了比较。研究发现,区域分析表

感觉神经性听力损失患者(SNHL)倾向于表现出语言发育延迟、执行功能缺陷和视觉认知障碍,甚至是听力扩大和耳蜗移植介入之后,仍旧表现出上述情况,表明了SNHL患者中大脑结构和功能已经发生了改变。

最近,有研究人员调查了30名SNHL儿童中大脑MRI结构情况(18名轻度到中度SNHL(M-M),12名重度到永久性SNHL(M-P)),并与性别和年龄相匹配的正常对照(NC)进行了比较。研究发现,区域分析表明了SNHL和NC之间,大脑、基底神经节、小脑和心室的体积没有统计学显著差异。表面分析表明,整体和大叶皮质表面积、厚度和体积在SNHL和NC参与者之间没有统计学显著差异。而左枕中皮层和左枕下皮层中,区域表面积、皮质厚度和皮质体积在M-P SNHL中与NC相比显著更小(p<0.02)。这些区域已知与高级视觉认知相关,包括了人类颞中区、枕侧区、枕面区和V8。

最后,研究人员指出,M-P SNHL中区域厚度的减少可能与SNHL患者中视觉认知功能的异常有关。

原始出处:

Shiohama T, McDavid J, Levman J et al. The left lateral occipital cortex exhibits decreased thickness in children with sensorineural hearing loss. Int J Dev Neurosci. 04 Jun 2019

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1703782, encodeId=63e31e03782ab, content=<a href='/topic/show?id=6a2d53396e2' target=_blank style='color:#2F92EE;'>#感觉神经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53396, encryptionId=6a2d53396e2, topicName=感觉神经)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=62d530584661, createdName=chaojitidian, createdTime=Thu Sep 26 09:49:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035436, encodeId=2ed92035436dd, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Tue Jul 30 05:49:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306385, encodeId=c6701306385f8, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364497, encodeId=0a47136449e89, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1982313, encodeId=c4291982313bd, content=<a href='/topic/show?id=13b658e849' target=_blank style='color:#2F92EE;'>#Dev#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5878, encryptionId=13b658e849, topicName=Dev)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Fri Jul 05 11:49:00 CST 2019, time=2019-07-05, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1703782, encodeId=63e31e03782ab, content=<a href='/topic/show?id=6a2d53396e2' target=_blank style='color:#2F92EE;'>#感觉神经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53396, encryptionId=6a2d53396e2, topicName=感觉神经)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=62d530584661, createdName=chaojitidian, createdTime=Thu Sep 26 09:49:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035436, encodeId=2ed92035436dd, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Tue Jul 30 05:49:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306385, encodeId=c6701306385f8, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364497, encodeId=0a47136449e89, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1982313, encodeId=c4291982313bd, content=<a href='/topic/show?id=13b658e849' target=_blank style='color:#2F92EE;'>#Dev#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5878, encryptionId=13b658e849, topicName=Dev)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Fri Jul 05 11:49:00 CST 2019, time=2019-07-05, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1703782, encodeId=63e31e03782ab, content=<a href='/topic/show?id=6a2d53396e2' target=_blank style='color:#2F92EE;'>#感觉神经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53396, encryptionId=6a2d53396e2, topicName=感觉神经)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=62d530584661, createdName=chaojitidian, createdTime=Thu Sep 26 09:49:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035436, encodeId=2ed92035436dd, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Tue Jul 30 05:49:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306385, encodeId=c6701306385f8, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364497, encodeId=0a47136449e89, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1982313, encodeId=c4291982313bd, content=<a href='/topic/show?id=13b658e849' target=_blank style='color:#2F92EE;'>#Dev#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5878, encryptionId=13b658e849, topicName=Dev)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Fri Jul 05 11:49:00 CST 2019, time=2019-07-05, status=1, ipAttribution=)]
    2019-06-18 ysjykql
  4. [GetPortalCommentsPageByObjectIdResponse(id=1703782, encodeId=63e31e03782ab, content=<a href='/topic/show?id=6a2d53396e2' target=_blank style='color:#2F92EE;'>#感觉神经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53396, encryptionId=6a2d53396e2, topicName=感觉神经)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=62d530584661, createdName=chaojitidian, createdTime=Thu Sep 26 09:49:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035436, encodeId=2ed92035436dd, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Tue Jul 30 05:49:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306385, encodeId=c6701306385f8, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364497, encodeId=0a47136449e89, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1982313, encodeId=c4291982313bd, content=<a href='/topic/show?id=13b658e849' target=_blank style='color:#2F92EE;'>#Dev#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5878, encryptionId=13b658e849, topicName=Dev)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Fri Jul 05 11:49:00 CST 2019, time=2019-07-05, status=1, ipAttribution=)]
    2019-06-18 lsndxfj
  5. [GetPortalCommentsPageByObjectIdResponse(id=1703782, encodeId=63e31e03782ab, content=<a href='/topic/show?id=6a2d53396e2' target=_blank style='color:#2F92EE;'>#感觉神经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53396, encryptionId=6a2d53396e2, topicName=感觉神经)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=62d530584661, createdName=chaojitidian, createdTime=Thu Sep 26 09:49:00 CST 2019, time=2019-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035436, encodeId=2ed92035436dd, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Tue Jul 30 05:49:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306385, encodeId=c6701306385f8, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364497, encodeId=0a47136449e89, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Tue Jun 18 03:49:00 CST 2019, time=2019-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1982313, encodeId=c4291982313bd, content=<a href='/topic/show?id=13b658e849' target=_blank style='color:#2F92EE;'>#Dev#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5878, encryptionId=13b658e849, topicName=Dev)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Fri Jul 05 11:49:00 CST 2019, time=2019-07-05, status=1, ipAttribution=)]
    2019-07-05 fzwish20000

相关资讯

Int J Pediatr Otorhinolaryngol:亚临床传导性听力损失能够减小耳声发射幅度

畸变产物耳声发射(DPOAEs)是一种省时的、非侵入性的评估主动内耳力学完整性的方法。不幸的是,很轻微的传导性听力损失(CHL)的出现就能够显著的减少DPOAEs的临床应用。最近,有研究人员系统性的评估了CHL对DPOAE幅度的影响,并确定了是否耳朵特异性初级音调水平操作能够用于减弱CHL的影响,并回复DPOAE的测量能力。研究包括了30名年轻成年人(57只耳朵),且听力正常。研究发现,每一个CH

Laryngoscope:儿科单边耳聋和不对称听力损失成像发现

最近,有研究人员调查了计算机断层摄影(CT)和核磁共振(MRI)在儿科单边耳聋(SSD)和不对称听力损失(ASH)成像发现情况。研究包括了189名具有SSD和ASH的儿科患者,并对成像发现进行了比较。研究发现,170患者患有SSD,19名患者具有ASH。在SSD组,83名患者(48.8%)具有与听力损失相关的成像发现。在ASH组,上述成像发现在6名(31.6%)ASHw患者(较差耳朵听力为永久性听

JAMA Otolaryngol Head Neck Surg:听力阈值提高群体中自我报道良好听力的流行度和特征研究

听力损失的听觉测定证据并不总与自我报道的听力损失有关。最近,有研究人员确定了自我报道良好听力在一个听力测定定义为听力损失患者群体中的比例并鉴定了相关因子。研究发现,任何频率下>25dB HL的平均(SD)年龄为47.0(0.4),而PTA>25dB HL的平均年龄为52.5(1.1)。对于那些通过任何频率下>25dB定义的HL群体,744(56.1%)名为男性,629(43.9%

Laryngoscope:鼓膜穿孔患者中听力损失与中耳容积关系研究

最近,有研究人员调查了由鼓膜(TM)穿孔引起的传导性听力损失(CHL)程度与乳突-中耳体积之间的关系。研究人员招募了2010年到2018年之间的那些诊断为TM穿孔的患者,并且收集了他们的听力测定数据。根据来源自患者头部或颞骨CT的分割分析推算了患者的乳突-中耳容积(MMEV),之后,研究人员将推算的MMEV与来源于鼓室导抗测试的MMEV数据进行了比较。研究发现,来源自患者头部或颞骨CT的分割分析的

老年听力损失诊断与干预专家共识

随着老龄化的到来,老年听力损失越来越成为一个社会问题。我国现阶段的儿童听力康复成绩可圈可点,但对老年群体的听力康复关注度远远不够。

Aging (Albany NY):年龄相关的听力损失能够促进脑脊液tau水平和脑萎缩

年龄相关的听力损失(ARHL)被认为是认识损伤和痴呆的一种有希望改变的风险因子。尽管如此,是否年龄相关的听力损失与老年痴呆症(AD)的神经退行性生物标志物相关仍旧不清楚。最近,有研究人员在ADNI数据库中选择了ARHL的患者的数据。研究人员在多变量模型中,探索了ARHL与CSF β-淀粉样蛋白(Aβ)和tau测量值、脑部Aβ负载和皮质结构测量之间的相关性。研究发现,ARHL与更高的tau CSF水