ASCO GI 2015 :化疗+贝伐珠单抗加强治疗可改善进展期结直肠癌患者生存

2015-01-21 黄蕾蕾 中国医学论坛报

据TRIBE研究最近结果,对于转移性结直肠癌患者,FOLFOXIRI化疗与贝伐珠单抗联合方案优于标准FOLFIRI化疗与贝伐珠单抗联合方案。与后者相比,FOLFOXIRI+贝伐珠单抗联合方案将患者的总生存期延长了约4个月,且5年总生存率加倍。 主要研究作者、托斯卡纳肿瘤研究所肿瘤学家Chiara Cremolini:这项新方案极大地改善了患者生存,甚至包括相对预后不良者,结直肠癌的治疗向前迈出了

据TRIBE研究最近结果,对于转移性结直肠癌患者,FOLFOXIRI化疗与贝伐珠单抗联合方案优于标准FOLFIRI化疗与贝伐珠单抗联合方案。与后者相比,FOLFOXIRI+贝伐珠单抗联合方案将患者的总生存期延长了约4个月,且5年总生存率加倍。

主要研究作者、托斯卡纳肿瘤研究所肿瘤学家Chiara Cremolini:这项新方案极大地改善了患者生存,甚至包括相对预后不良者,结直肠癌的治疗向前迈出了值得骄傲的一步。我们相信,这一结果将会鼓励临床医生采用FOLFOXIRI+贝伐珠单抗联合方案作为身体条件较好患者的优先治疗选择。

ASCO观点

ASCO专家Smitha S. Krishnamurthi教授:诊断后5年生存的患者比例倍增,这一结果很重要而且吸引人。对于能够耐受三种化疗药物联合方案的患者,FOLFOXIRI与贝伐珠单抗联合是一项重要的治疗进步。

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    2015-09-14 licz0423
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    2015-05-27 quxin068
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