盘点:西兰花不仅抗癌,还有这些秘密!

2017-08-23 MedSci MedSci原创

西兰花是一种很受人们欢迎的蔬菜,它味道鲜美,营养也很高,还有很高的药用价值,而且维生素C含量非常丰富,具有抗癌功效,其功效已经被全世界人认可,西兰花的平均营养价值及防病作用远远超出其他蔬菜,名列第一。梅斯医学小编汇总了近期关于西兰花研究的新发现,与大家分享!【1】Sci Rep:西兰花,又一项功效将被证实!http://www.medsci.cn/article/show_article.do

西兰花是一种很受人们欢迎的蔬菜,它味道鲜美,营养也很高,还有很高的药用价值,而且维生素C含量非常丰富,具有抗癌功效,其功效已经被全世界人认可,西兰花的平均营养价值及防病作用远远超出其他蔬菜,名列第一。梅斯医学小编汇总了近期关于西兰花研究的新发现,与大家分享!

【1】Sci Rep:西兰花,又一项功效将被证实!

骨关节炎是造成人残疾的主要原因,目前还没有可以预防或减慢疾病进展的药物。饮食建议或补充因其毒性低且易于实施管理而成为治疗该疾病的一个很有吸引力的选择。本实验组既往研究已经证明,西兰花中的萝卜硫素——一种来自其芥子油苷前体的膳食异硫氰酸酯,在体外和体内的骨关节炎模型中均发现萝卜硫素可预防细胞中的软骨破坏。

研究人员选择了40例接受全膝关节置换术的膝关节骨关节炎患者进行此验证试验。术前随机将患者分为低或高硫代葡萄糖苷饮食组,干预处理14天。结果显示,高硫代葡萄糖苷酸饮食组患者的关节滑液中检测到异硫氰酸酯,而低硫代葡萄糖苷酸饮食组则未检测到。表明患者体内血浆中异硫氰酸酯的水平升高,特别是萝卜硫烷。关节滑液蛋白质组学分析显示,两组患者关节滑液内有125个蛋白质表达存在明显差异。

研究结果表明,萝卜硫素或可影响骨关节炎患者的临床结局,本研究所发现的功能性作用也将在一项临床试验中进行测试。

【2】Science Translational Medicine:西兰花可能是一种天然“降糖药”

2型糖尿病如今越来越普遍,但并非所有的患者都可以被现有的药物成功治疗。科学家们也在寻找新方法帮助糖尿病患者控制血糖。近日,来自瑞典,美国和瑞士的一组研究人员发现,十字花科蔬菜中常见的化合物萝卜硫素能够减少大鼠肝细胞的葡萄糖的产生,并改善糖尿病患者的空腹血糖。这项研究于近日发表在Science Translational Medicine上。

全球成年糖尿病患者数量已达4.15亿。糖尿病常见的治疗方法包括控制饮食和服用二甲双胍等药物。但是,糖尿病药物也可能会导致肝损伤等其他问题,因此研究人员试图寻找药物替代品。

在这项新研究中,研究人员分析了与2型糖尿病相关的基因表达模式并将其与数千种候选药物的基因标志进行比较,以寻找与肝细胞中基因表达特异性相关的化合物。研究人员最终从这些化合物中发现了萝卜硫素——这种在西兰花等十字花科蔬菜中常见的天然化合物对糖尿病相关的基因表达显示出强烈的影响。

然后,研究人员培养了来自2型糖尿病大鼠中的肝细胞,并用萝卜硫素进行处理。结果发现,萝卜硫素能够抑制培养细胞中的葡萄糖产生,并且还能改善高脂或高糖饮食的啮齿动物的葡萄糖耐受性。鉴于细胞和动物实验的结果令人乐观,接下来研究人员进行了临床实验。他们在12周时间内对97名肥胖的2型糖尿病患者检测了萝卜硫素的功效。发现被萝卜硫素治疗的患者空腹时葡萄糖水平显着降低。不过,这项研究结果尚在早期阶段,还需要对萝卜硫素的功效进行更多的验证,以证明这种化合物或仅仅通过食用西兰花等蔬菜就有可能替代2型糖尿病的药物。

【3】JNB:“西兰花”可以有效预防前列腺癌

研究发现萝卜硫素,一种已知有助于预防前列腺癌的来自西兰花的饮食化合物,可能通过其对长的非编码 RNA 的影响而发挥作用。这是癌症发展史上一个引人注目的进步。研究结果由俄勒冈州立大学的营养生物学杂志的研究人员发表。

研究提供了更多的证据,证明这些 lncRNA,曾经被认为是一种没有特别价值或功能的“垃圾 DNA”,可能在触发细胞变得恶性和扩散方面发挥关键作用。

这项研究表明,一种称为 LINC01116 的 lncRNA 在前列腺癌的人类细胞系中被上调,但是可以通过用萝卜硫素处理来减少。数据“加强了这样的想法,lncRNAs 是化学预防研究的一个令人兴奋的新途径,从饮食中得到的化学物质可以改变他们的表达。

在男性中,前列腺癌是全球第二最常诊断的癌症,并且是美国癌症相关死亡的第二主要原因。研究人员说:“值得注意的是,增加消费的十字花科蔬菜,如西兰花,高萝卜硫素,似乎与降低发展前列腺癌的风险相关联。

【4】Cell Metab:西兰花中富含的天然化合物可延缓衰老

来自华盛顿大学医学院的科学家发现,为健康小鼠补充一种名为NMN(烟酰胺单核苷酸)天然化合物可以抵消这种产能损失,减少一些典型的衰老症状比如,体重增加,胰岛素敏感性降低以及身体活动减少等等。这项研究发表于10月27日的Cell Metabolism杂志上。研究人员表示,他们已经可以减缓衰老小鼠的生理减退。并使衰老的小鼠代谢及能量水平与年轻小鼠相似。由于人类细胞同样依赖于这种能量产生过程,研究人员希望这一发现可以为治疗一些衰老相关疾病的提供新方法。
随着年龄增长,能量代谢过程中的一个关键成分NAD(烟酰胺腺嘌呤二核苷酸)在体内的水平逐渐下降。此前的研究表明,衰老的小鼠多种组织中NAD水平都出现下降。但是,一些研究显示直接给予小鼠NAD并不是一个有效缓解衰老症状的方法,因此,研究人员希望寻找一种间接的方法提升NAD水平。他们找到了NAD供应链上游的化合物NMN。

研究人员发现,补充NMN对机体产生了诸多有益影响,包括骨骼肌、肝功能、骨密度、眼功能、胰岛素敏感性、免疫功能、体重和体力活动水平。但是NMN的这些益处只在年龄较大的小鼠中有明显作用。对年轻小鼠没有显著作用,这可能是因为年轻的小鼠自身能够产生足量的NMN。研究人员认为,伴随着衰老的炎症增加可能削弱了机体产生NMN的能力,继而引起NAD减少。

研究人员还发现,在骨骼肌中,给予NMN可以通过改善线粒体功能提升帮助能量代谢。尽管补充NMN的小鼠消耗了更多的食物,但它们随着年龄而增长的体重更少,这可能是因为它们的代谢水平提升为生理活动产生了更多能量。此外,补充NMN还可以改善小鼠视网膜的功能,增加泪液分泌,提升胰岛素敏感性等。

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    2017-08-26 戒馋,懒,贪

    超厉害的说

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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Aug 24 09:07:01 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236593, encodeId=e4d1236593a1, content=西兰花是一种很受人们欢迎的蔬菜.它味道鲜美.营养也很高.还有很高的药用价值.而且维生素C含量非常丰富.具有抗癌功效.其功效已经被全世界人认可.西兰花的平均营养价值及防病作用远远超出其他蔬菜.名列第一, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Thu Aug 24 08:47:34 CST 2017, time=2017-08-24, status=1, ipAttribution=), 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    2017-08-25 wei834766788

    gghjjkfjkkkk

    0

  3. 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    2017-08-25 明天会更好!

    谢谢分享谢谢分享!

    0

  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Aug 24 09:07:01 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236593, encodeId=e4d1236593a1, content=西兰花是一种很受人们欢迎的蔬菜.它味道鲜美.营养也很高.还有很高的药用价值.而且维生素C含量非常丰富.具有抗癌功效.其功效已经被全世界人认可.西兰花的平均营养价值及防病作用远远超出其他蔬菜.名列第一, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Thu Aug 24 08:47:34 CST 2017, time=2017-08-24, status=1, ipAttribution=), 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    2017-08-25 186****0580(小山羊)

    学习了谢谢了

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Aug 24 09:07:01 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236593, encodeId=e4d1236593a1, content=西兰花是一种很受人们欢迎的蔬菜.它味道鲜美.营养也很高.还有很高的药用价值.而且维生素C含量非常丰富.具有抗癌功效.其功效已经被全世界人认可.西兰花的平均营养价值及防病作用远远超出其他蔬菜.名列第一, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3wrgsNyr5lh6N2MY5xSnbvo4g5sRlc3MZoDdWpMeSdozUCPNhA96wndwQe3X5Z5oYMNxVUdOib63nw/0, createdBy=d8d11998754, createdName=Julie W, createdTime=Thu Aug 24 08:47:34 CST 2017, time=2017-08-24, status=1, ipAttribution=), 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    2017-08-24 flyingzyx

    谢谢分享.

    0

  7. 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    2017-08-24 damiao93

    学习了.感谢分享

    0

  8. 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    2017-08-24 戒馋,懒,贪

    超厉害的说

    0

  9. 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    2017-08-24 Julie W

    西兰花是一种很受人们欢迎的蔬菜.它味道鲜美.营养也很高.还有很高的药用价值.而且维生素C含量非常丰富.具有抗癌功效.其功效已经被全世界人认可.西兰花的平均营养价值及防病作用远远超出其他蔬菜.名列第一

    0

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    2017-08-24 cmn

    西兰花营养价值最高

    0

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