Diabetic Med:白蛋白和胆固醇水平与内科入院患者的低血糖发生率的关系

2018-12-28 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于白蛋白和胆固醇水平与内科入院患者的低血糖发生率的关系的研究。研究入院时血清白蛋白和胆固醇水平与内科入院患者发生低血糖的关系。 在这个横断面分析中,研究人员检查了内科住院患者的电子病历。提取的数据包括其在入院时所有葡萄糖测量值以及血清白蛋白和胆固醇。如果在住院期间至少一次记录葡萄糖测量≤3.9mmol/ l的,则为低血糖事件。回归

近日,国际杂志 《Diabetic Med》上在线发表一项关于白蛋白和胆固醇水平与内科入院患者的低血糖发生率的关系的研究。研究入院时血清白蛋白和胆固醇水平与内科入院患者发生低血糖的关系。

在这个横断面分析中,研究人员检查了内科住院患者的电子病历。提取的数据包括其在入院时所有葡萄糖测量值以及血清白蛋白和胆固醇。如果在住院期间至少一次记录葡萄糖测量≤3.9mmol/ l的,则为低血糖事件。回归分析用于确定哪些临床指标可预测低血糖。

在研究期间, 45 224人(平均年龄68.9±17.8岁,男性49.4%,糖尿病21.1%)从内科出院。7.5%的发生了低血糖(15.4%的糖尿病患者与5.5%的患者没有; P <0.001)。Logistic回归分析显示血清白蛋白[优势比(OR0.908,95%置信区间(CI0.896-0.919; P <0.001)和胆固醇(OR 0.938,95CI 0.896-0.981; P.= 0.005]与低血糖事件显著相关。即使对照了年龄,性别,住院期间的平均血糖,住院时间,入院时的急性感染糖尿病状态,血红蛋白,白细胞计数和C-反应水平,结果仍然显著。入院时低白蛋白血症(<35 g/l)和低胆固醇血症(<3.37 mmol/l)的组合大大增加了发生低血糖的风险(OR 2.544,95CI 2.096-3.088; P<0.001)。

研究表明,低白蛋白血症和低胆固醇血症可预测有无糖尿病的患者在医院环境中发生的低血糖事件。

原始出处:

E. LeibovitzJ. WainsteinM. Boazet al. Association of albumin and cholesterol levels with incidence of hypoglycaemia in people admitted to general internal medicine units

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    2018-12-30 珙桐
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  8. [GetPortalCommentsPageByObjectIdResponse(id=1970695, encodeId=c33519e0695e8, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Fri Nov 01 02:05:00 CST 2019, time=2019-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760978, encodeId=b27f1e60978f7, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sat Aug 10 04:05:00 CST 2019, time=2019-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1748114, encodeId=977e1e4811463, content=<a href='/topic/show?id=9f672636086' target=_blank style='color:#2F92EE;'>#低血糖发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26360, encryptionId=9f672636086, topicName=低血糖发生率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aea936056349, createdName=DEXTER3151, createdTime=Thu Jan 31 02:05:00 CST 2019, time=2019-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826502, encodeId=912f1826502af, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Nov 22 10:05:00 CST 2019, time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638947, encodeId=e456163894e07, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Nov 23 12:05:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304637, encodeId=d1fb130463e46, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Sun Dec 30 01:05:00 CST 2018, time=2018-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609429, encodeId=4ca91609429a6, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Dec 30 01:05:00 CST 2018, time=2018-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=356712, encodeId=6318356e12c2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sun Dec 30 00:36:08 CST 2018, time=2018-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=356607, encodeId=8bd835660ed8, content=学习了,谢谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Fri Dec 28 13:51:41 CST 2018, time=2018-12-28, status=1, ipAttribution=)]
    2018-12-30 smartxiuxiu

    不错

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1970695, encodeId=c33519e0695e8, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Fri Nov 01 02:05:00 CST 2019, time=2019-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760978, encodeId=b27f1e60978f7, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sat Aug 10 04:05:00 CST 2019, time=2019-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1748114, encodeId=977e1e4811463, content=<a href='/topic/show?id=9f672636086' target=_blank style='color:#2F92EE;'>#低血糖发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26360, encryptionId=9f672636086, topicName=低血糖发生率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aea936056349, createdName=DEXTER3151, createdTime=Thu Jan 31 02:05:00 CST 2019, time=2019-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826502, encodeId=912f1826502af, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Nov 22 10:05:00 CST 2019, time=2019-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638947, encodeId=e456163894e07, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Nov 23 12:05:00 CST 2019, time=2019-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1304637, encodeId=d1fb130463e46, content=<a href='/topic/show?id=cd37e1767b5' target=_blank style='color:#2F92EE;'>#白蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71767, encryptionId=cd37e1767b5, topicName=白蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25d7319, createdName=珙桐, createdTime=Sun Dec 30 01:05:00 CST 2018, time=2018-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609429, encodeId=4ca91609429a6, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Dec 30 01:05:00 CST 2018, time=2018-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=356712, encodeId=6318356e12c2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Sun Dec 30 00:36:08 CST 2018, time=2018-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=356607, encodeId=8bd835660ed8, content=学习了,谢谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Fri Dec 28 13:51:41 CST 2018, time=2018-12-28, status=1, ipAttribution=)]
    2018-12-28 明崖

    学习了,谢谢作者分享

    0

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