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JCLA：急性ST段抬高型心肌梗死患者经皮冠状动脉介入治疗后血清类风湿因子水平与无再流现象的关系

2019-01-18 MedSci MedSci原创

急性ST段抬高心肌梗死
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本研究旨在评价急性ST段抬高型心肌梗死(STEMI)患者行首次经皮冠状动脉介入治疗(PCI)后血清类风湿因子(RF)水平与无再流现象的关系。 研究人员采用横断面研究，共纳入318例连续诊断为STEMI的患者，在症状出现12小时内进行原发性PCI。测量所有患者血清RF基线水平。定义无回流现象的诊断为TIMI II或更少的血流，不存在夹层、机械梗阻、明显残余狭窄或其他似是而非的原因。根据梗死相关

本研究旨在评价急性ST段抬高型心肌梗死(STEMI)患者行首次经皮冠状动脉介入治疗(PCI)后血清类风湿因子(RF)水平与无再流现象的关系。

研究人员采用横断面研究，共纳入318例连续诊断为STEMI的患者，在症状出现12小时内进行原发性PCI。测量所有患者血清RF基线水平。定义无回流现象的诊断为TIMI II或更少的血流，不存在夹层、机械梗阻、明显残余狭窄或其他似是而非的原因。根据梗死相关动脉蒂米血流溶栓的血管造影特点，将患者分为回流组(n = 283)和无回流组(n = 46)。

结果显示，13.8%的患者无再流现象。中位RF水平无回流组明显高于回流组(18.5 (7.0 27.6)vs 8.0 (4.6 50.8)， P < .001)。有条件的逻辑回归分析表明,身体质量指数(或= 0.845,95% CI:0.765 ~ 0.933,P =措施)、糖尿病(或= 5.257,95% CI:1.124 ~ 24.587,P =0.35)；基线射频级别(或= 1.198,95% CI:1.108 ~ 1.295,P <0.01)；和SYNTAX (或= 1.065,95% CI:1.025 ~ 1.107,P =0.01)是无复流现象的独立预测指标。

研究结果表明，基线血RF浓度与急性STEMI原发性PCI患者无回流现象独立相关。

原始出处：

Alaa Quisi, Gökhan Alıcı, The relationship between serum rheumatoid factor level and no‐reflow phenomenon in patients with acute ST‐segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

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    #类风湿#

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  5. [GetPortalCommentsPageByObjectIdResponse(id=2028154, encodeId=1479202815400, content=<a href='/topic/show?id=e9afe61713e' target=_blank style='color:#2F92EE;'>#类风湿因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76171, encryptionId=e9afe61713e, topicName=类风湿因子)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Sat Oct 26 09:26:00 CST 2019, time=2019-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1648947, encodeId=617b164894efc, content=<a href='/topic/show?id=6e0630843d0' target=_blank style='color:#2F92EE;'>#冠状动脉介入治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30843, encryptionId=6e0630843d0, topicName=冠状动脉介入治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9ec23698107, createdName=3631181, createdTime=Fri Sep 06 08:26:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320757, encodeId=478a1320e5782, content=<a href='/topic/show?id=cd29e838938' target=_blank style='color:#2F92EE;'>#经皮冠状动脉介入治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78389, encryptionId=cd29e838938, topicName=经皮冠状动脉介入治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334108, encodeId=3b28133410887, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423077, encodeId=49f414230e703, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624403, encodeId=9446162440344, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=)]
    2019-01-20 gdsun

    #ST段抬高#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2028154, encodeId=1479202815400, content=<a href='/topic/show?id=e9afe61713e' target=_blank style='color:#2F92EE;'>#类风湿因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76171, encryptionId=e9afe61713e, topicName=类风湿因子)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Sat Oct 26 09:26:00 CST 2019, time=2019-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1648947, encodeId=617b164894efc, content=<a href='/topic/show?id=6e0630843d0' target=_blank style='color:#2F92EE;'>#冠状动脉介入治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30843, encryptionId=6e0630843d0, topicName=冠状动脉介入治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a9ec23698107, createdName=3631181, createdTime=Fri Sep 06 08:26:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1320757, encodeId=478a1320e5782, content=<a href='/topic/show?id=cd29e838938' target=_blank style='color:#2F92EE;'>#经皮冠状动脉介入治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78389, encryptionId=cd29e838938, topicName=经皮冠状动脉介入治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334108, encodeId=3b28133410887, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423077, encodeId=49f414230e703, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624403, encodeId=9446162440344, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Sun Jan 20 04:26:00 CST 2019, time=2019-01-20, status=1, ipAttribution=)]
    2019-01-20 hyf035

    #ST段#

    0