DIABETOLOGIA:久坐时间,更高强度的身体活动或心肺健康,哪个对于心脏代谢健康更重要

2018-12-01 MedSci MedSci原创

本研究目的是调查久坐时间(ST),高强度体力活动(HPA)和心肺健康(CRF)与代谢综合征和糖尿病状态的独立和组合(横断面)关联。 使用activPAL3测量1933个成人(年龄40-75岁)ST和HPA(中度至剧烈体力活动的替代指标)。通过次最大循环测力计测试评估CRF。根据成人治疗专家组(ATP)III指南定义代谢综合征。从OGTT确定糖尿病状态(正常,前驱糖尿病[即葡萄糖耐量降低和/或

本研究目的是调查久坐时间(ST),高强度体力活动(HPA)和心肺健康(CRF)与代谢综合征糖尿病状态的独立和组合(横断面)关联。

使用activPAL3测量1933个成人(年龄40-75岁)STHPA(中度至剧烈体力活动的替代指标)。通过次最大循环测力计测试评估CRF。根据成人治疗专家组(ATPIII指南定义代谢综合征。从OGTT确定糖尿病状态(正常,前驱糖尿病[即葡萄糖耐量降低和/或空腹血糖受损]2型糖尿病)。分别根据STHPACRF以及ST-CRFHPA-CRF的组合计算代谢综合征,采用(多项式)逻辑回归分析前驱糖尿病和2型糖尿病的可能性。

结果显示,较高的ST,较低的HPA和较低的CRF与代谢综合征和2型糖尿病相互独立的可能性更大。与具有高CRF和高HPACRF  -HPA )的个体相比,无论HPA如何,具有较低CRF的组中代谢综合征和2型糖尿病的可能性较高。低CRF和低HPACRF  -HPA )的个体患代谢综合征(OR 5.73 [95CI 3.84,8.56])和2型糖尿病的风险特别高(OR 6.42 [95CI 3.95,10.45] )。类似地,与具有高CRF和低STCRF  -ST 低)的那些相比),具有中等或低CRF的患者代谢综合征,前驱糖尿病和2型糖尿病的可能性较高,但与ST无关。在CRF较高的患者中,高ST值与代谢综合征(OR 2.93 [95CI 1.72,4.99])和2型糖尿病(OR 2.21 [95CI 1.17,4.17])相关。在低CRF和高STCRF  -ST )的个体中观察到代谢综合征和2型糖尿病的几率最高(OR [95CI]:代谢综合征,9.22 [5.74,14.80]; 2型糖尿病,8.38 [4.83,14.55])。

这些数据表明STHPACRF都应该成为监测目标,以便最佳地降低代谢综合征和2型糖尿病的风险。

原始出处:

Jeroen H. P. M. van der Velde, Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study

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  7. 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  8. 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createdBy=fffc37235404, createdName=yanjie6253_56072854, createdTime=Thu Sep 19 03:18:00 CST 2019, time=2019-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1928542, encodeId=5ca4192854232, content=<a href='/topic/show?id=6c2d513392c' target=_blank style='color:#2F92EE;'>#心肺健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51339, encryptionId=6c2d513392c, topicName=心肺健康)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6ac207, createdName=xlwang2691, createdTime=Fri Jun 28 03:18:00 CST 2019, time=2019-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638883, encodeId=a6fb163888349, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, 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encryptionId=67b81023e6ea, topicName=高强度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79d219134728, createdName=aids219, createdTime=Mon Dec 03 02:18:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354179, encodeId=a07c3541e991, content=认真学习,不断进步,把经验分享给同好。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Sat Dec 01 12:30:56 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
  9. 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createdName=smlt2009, createdTime=Mon Dec 03 02:18:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571393, encodeId=f82615e13935c, content=<a href='/topic/show?id=fcf425411da' target=_blank style='color:#2F92EE;'>#代谢健康#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25411, encryptionId=fcf425411da, topicName=代谢健康)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e7a515732936, createdName=宋威, createdTime=Mon Dec 03 02:18:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604024, encodeId=715f160402492, content=<a href='/topic/show?id=67b81023e6ea' target=_blank style='color:#2F92EE;'>#高强度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102376, encryptionId=67b81023e6ea, topicName=高强度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=79d219134728, createdName=aids219, createdTime=Mon Dec 03 02:18:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354179, encodeId=a07c3541e991, content=认真学习,不断进步,把经验分享给同好。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Sat Dec 01 12:30:56 CST 2018, time=2018-12-01, status=1, ipAttribution=)]
    2018-12-03 aids219
  10. 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