J Endod:混合添加物对于5.25%次氯酸钠溶液理化特性的影响

2017-11-21 lishiting MedSci原创

这篇研究是第一次报道混合添加物(聚乙二醇400, Triton X-100, 苯扎氯铵和甲酸乙酯)对5.25%次氯酸钠冲洗液表面张力、pH和粘接系数的影响。并首次在牙科学中应用依赖于非监督式多变量分析的高级统计学方法定量改良次氯酸钠(NaOCl)溶液理化特性的变异性。

这篇研究是第一次报道混合添加物(聚乙二醇400, Triton X-100, 苯扎氯铵和甲酸乙酯)对5.25%次氯酸钠冲洗液表面张力、pH和粘接系数的影响。并首次在牙科学中应用依赖于非监督式多变量分析的高级统计学方法定量改良次氯酸钠(NaOCl)溶液理化特性的变异性。研究对5.25% NaOCl溶液添加不同浓度的添加物,在22°C和37°C检测其理化特性参数的变化,结果进行统计学分析并阐明添加物的作用。聚类分析和主成分分析表明,pH和表面张力是改良溶液组显著变化的参数(P < .05)。4种主要成分占方差总量的90.6%,与聚乙二醇引起的流动特性(37.3%)相关;湿润性(22.5%和10.5%)依赖于离子和非离子型表面活化剂;抗微生物活性(20.3%)受到甲酸乙酯的影响。主要成分的Varimax旋转结果显示,离子型表面活化剂(苯扎氯铵)与非离子型表面活化剂(Triton-X)相比可以显著减小表面张力。尽管甲酸乙酯在添加剂中作为气味改良剂,但它对pH值降低、O2发泡效应的发生以及次氯酸的释放具有明显作用。结论:统计结果显示,5.25% NaOCl冲洗液应该通过添加0.1%苯扎氯铵

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