NEJM:结核性心包炎-病例报道

2018-05-17 xing.T MedSci原创

该患者接受心包穿刺术,直接抽吸1400ml化脓液后,血流动力学稳定,放置心包引流。心包液腺苷脱氨酶水平为100 U/ml(参考范围为0-9),心包液检查显示抗酸杆菌阳性。诊断为结核性心包炎。人类免疫缺陷病毒检测阳性。

患者为一名29岁的妇女,因疲劳和虚弱恶化1个月,伴发热和呼吸困难2周而到急诊就诊。她在就诊前9年从安哥拉移民。

温度为39.5°C,血压为80/50mmHg,心率为每分钟135次,呼吸速率为每分钟32次。经检查,患者颈部静脉扩张,心音消沉。心电图显示窦性心动过速和下肢和心前导联低电压。经胸超声心动图显示有大量心包积液并伴有压塞现象(如图A(箭头)所示)。渗出液含有广泛的心包纤维蛋白链,呈虫状外观(如图B)。



该患者接受心包穿刺术,直接抽吸1400ml化脓液后,血流动力学稳定,放置心包引流。心包液腺苷脱氨酶水平为100 U/ml(参考范围为0-9),心包液检查显示抗酸杆菌阳性。诊断为结核性心包炎。人类免疫缺陷病毒检测阳性。

患者服用异烟肼、利福平、吡嗪酰胺和乙胺丁醇治疗2个月,随后用利福平和异烟肼再治疗4个月连同泼尼松龙治疗6周以预防缩窄性心包炎。该患者还启动了抗逆转录病毒治疗。发热在治疗的第一周内就消失了。

原始出处:

Daniel Faria,et al. Tuberculous Pericarditis.N Engl J Med 2018. https://www.nejm.org/doi/full/10.1056/NEJMicm1709552#nav

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    2018-06-09 沙漠浪人

    结核性心包炎

    0

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    2018-05-24 沙漠浪人

    结核性心包炎

    0

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    2018-05-17 龙胆草

    学习谢谢分享

    0

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    2018-05-17 飛歌

    厉害了我的国

    0

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    2018-05-17 易水河

    学习学习.不错

    0