Thyroid:长期食盐加碘对甲状腺疾病的疗效和安全性分析

2020-02-27 xing.T MedSci原创

由此可见,长期USI并及时调整可成功预防碘缺乏症,而且似乎是安全的。对于人群稳定的碘摄入量中位数最高为300 µg/L,其收益要大于风险。

强制性食盐加碘(USI)在中国已经实施了20年。尽管可以有效地控制碘缺乏症,但人们仍在讨论过量碘的风险。

近日,甲状腺疾病领域权威杂志Thyroid上发表了一篇研究文章,研究人员进行了一项全国代表性的横断面研究,来自中国31个省的78470名18岁或以上的参与者参加了研究。参与者接受了甲状腺的问卷调查和B型超声检查,并测量了血清甲状腺激素、甲状腺抗体和尿碘浓度(UIC)。

成人的UIC中位数为177.89 µg/L。成人甲状腺疾病的加权患病率如下:显性甲状腺功能亢进症为0.78%,亚临床甲状腺功能亢进症为0.44%, Graves’病为0.52%,甲状腺功能减退症为1.02%,亚临床甲状腺功能减退症为12.93%,甲状腺抗体(Ab)阳性占14.19%,TPOAb阳性占10.19%,TgAb阳性占9.70%,甲状腺肿为1.17%,甲状腺结节为20.43%。碘过量仅与较高的甲状腺功能亢进和亚临床甲状腺功能减退几率相关,而碘缺乏与大多数甲状腺疾病的高几率显著相关。此外,碘摄入量的增加与血清TSH水平升高显著相关,但与甲状腺抗体和甲状腺结节呈负相关。

由此可见,长期USI并及时调整可成功预防碘缺乏症,而且似乎是安全的。对于人群稳定的碘摄入量中位数最高为300 µg/L,其收益要大于风险。

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    2020-02-29 lingqf
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    2020-02-27 内科新手

    谢谢梅斯提供这么好的信息,学到很多

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