BMC Obesity:肥胖对于抑郁症有缓解作用

2019-03-18 不详 MedSci原创

肥胖与抑郁之间的关系很复杂。本研究评估了体重指数(BMI)对BMI,炎症,氧化应激,睡眠质量和抑郁症状之间关系。

背景
肥胖与抑郁之间的关系很复杂。本研究评估了体重指数(BMI)对BMI,炎症,氧化应激,睡眠质量和抑郁症状之间关系。

方法
研究人员对2005-2008年美国国家健康和营养检查调查分析中的9133名年龄大于20岁的患者进行了回顾性分析。通过问卷评分确定抑郁症状和睡眠质量。C-反应蛋白(CRP)用作炎症的生物标志物,γ-谷氨酰转移酶用于评估氧化应激。使用回归模型评估抑郁症状,睡眠质量和生物标志物之间的关系。测试了BMI和性别的调节作用。

结果
BMI是γ-谷氨酰转移酶与抑郁症状之间关系的重要调节因子(p= 0.02),但不是CRP或睡眠质量的影响因素。女性抑郁症状随BMI升高而增强:BMI≥25~30kg / m 2时为3.17;BMI≥30~35kg /m 2为3.92,BMI≥35kg / m 2为7.38。在没有抑郁症状的患者中,BMI也是γ-谷氨酰转移酶水平的显着调节因子。在调整炎症,氧化应激和其他混杂因素后,那些有抑郁症状的人的睡眠质量比没有抑郁症状的人低24%。

结论
氧化应激和抑郁症状之间的联系可能在女性患者中与肥胖更加明显。患有抑郁症状的人也会大大降低睡眠质量。

原始出处:

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    2019-05-17 zhanglin3079
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    2019-04-02 你的水果

    看了半天我没看出来肥胖咋缓解抑郁了,有大神解说么

    0

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    2019-03-20 lingaifan
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    2019-03-20 skhzy

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